imipramine has been researched along with Neuroleptic Malignant Syndrome in 10 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serotonin syndrome (SS) and neuroleptic malignant syndrome (NMS) are life-threatening adverse reactions caused by serotonergic antidepressants and neuroleptics, respectively." | 1.42 | Serotonin syndrome overlapping with neuroleptic malignant syndrome: A case report and approaches for differentially diagnosing the two syndromes. ( Nisijima, K, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lopez, E | 1 |
| Fraile, S | 1 |
| Hidalgo, FJ | 1 |
| García, B | 1 |
| Nisijima, K | 1 |
| Khandelwal, V | 1 |
| Gupta, N | 1 |
| Agarwal, A | 1 |
| Goyal, RK | 1 |
| Kawabata, M | 1 |
| Kubo, I | 1 |
| Suzuki, K | 1 |
| Terai, T | 1 |
| Iwama, T | 1 |
| Isobe, M | 1 |
| Real Rodríguez, B | 1 |
| Ruibal, JL | 1 |
| Grande Rodríguez, S | 1 |
| Sueiro Pita, B | 1 |
| Bui, HD | 1 |
| Chaney, RH | 1 |
| Chen, YG | 1 |
| Merriam, AE | 2 |
| Schibuk, M | 1 |
| Schachter, D | 1 |
1 review available for imipramine and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
[The neuroleptic malignant syndrome in an adolescent. Its treatment with dantrolene, bromocryptin and diazepam].
Topics: Adolescent; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antiparkinson Agents; Antipsychot | 1996 |
9 other studies available for imipramine and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
[Possible malignant neuroleptic syndrome associated with aripiprazole and imipramine and treated with bromocriptine].
Topics: Antipsychotic Agents; Aripiprazole; Bromocriptine; Combined Modality Therapy; Drug Therapy, Combinat | 2013 |
Serotonin syndrome overlapping with neuroleptic malignant syndrome: A case report and approaches for differentially diagnosing the two syndromes.
Topics: Antidepressive Agents, Tricyclic; Clinical Decision-Making; Cyproheptadine; Dantrolene; Depressive D | 2015 |
Tricyclic antidepressant overdose presenting as neuroleptic malignant syndrome.
Topics: Adult; Antidepressive Agents, Tricyclic; Drug Overdose; Humans; Imipramine; Male; Neuroleptic Malign | 2002 |
'Tako-Tsubo cardiomyopathy' associated with syndrome malin: reversible left ventricular dysfunction.
Topics: 3-Iodobenzylguanidine; Aged; Amantadine; Antidepressive Agents, Tricyclic; Cardiomyopathies; Coronar | 2003 |
Transient hepatitis due to low dose neuroleptic medication.
Topics: Adult; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Humans; Imipramine; Male; Ne | 1989 |
[Malignant syndromes due to psychotherapeutic agents].
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Imipramine; Ma | 1987 |
Withdrawal NMS after drug treatment.
Topics: Amitriptyline; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Neuroleptic Malignant Syn | 1988 |
Neuroleptic malignant syndrome after imipramine withdrawal.
Topics: Adult; Female; Humans; Imipramine; Neuroleptic Malignant Syndrome; Substance Withdrawal Syndrome | 1987 |
A role for catecholamines in the pathogenesis of neuroleptic malignant syndrome.
Topics: Akathisia, Drug-Induced; Brain Chemistry; Catecholamines; Chlorpromazine; Haloperidol; Humans; Imipr | 1986 |