Page last updated: 2024-10-29

imipramine and Neurodegenerative Diseases

imipramine has been researched along with Neurodegenerative Diseases in 2 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.

Research Excerpts

ExcerptRelevanceReference
"The aim of our work was to study effect of antidepressant imipramine on both thapsigargin- and tunicamycin-induced ER stress and mitochondrial dysfunction in neuroblastoma SH-SY5Y cells."8.02Differential impact of imipramine on thapsigargin- and tunicamycin-induced endoplasmic reticulum stress and mitochondrial dysfunction in neuroblastoma SH-SY5Y cells. ( Brodnanova, M; Cibulka, M; Evinova, A; Hatokova, Z; Racay, P, 2021)
"The aim of our work was to study effect of antidepressant imipramine on both thapsigargin- and tunicamycin-induced ER stress and mitochondrial dysfunction in neuroblastoma SH-SY5Y cells."4.02Differential impact of imipramine on thapsigargin- and tunicamycin-induced endoplasmic reticulum stress and mitochondrial dysfunction in neuroblastoma SH-SY5Y cells. ( Brodnanova, M; Cibulka, M; Evinova, A; Hatokova, Z; Racay, P, 2021)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Brodnanova, M1
Hatokova, Z1
Evinova, A1
Cibulka, M1
Racay, P1
Kolisek, M1
Montezano, AC1
Sponder, G1
Anagnostopoulou, A1
Vormann, J1
Touyz, RM1
Aschenbach, JR1

Other Studies

2 other studies available for imipramine and Neurodegenerative Diseases

ArticleYear
Differential impact of imipramine on thapsigargin- and tunicamycin-induced endoplasmic reticulum stress and mitochondrial dysfunction in neuroblastoma SH-SY5Y cells.
    European journal of pharmacology, 2021, Jul-05, Volume: 902

    Topics: Cell Death; Cell Line, Tumor; Cell Survival; Endoplasmic Reticulum Stress; Endoribonucleases; Humans

2021
PARK7/DJ-1 dysregulation by oxidative stress leads to magnesium deficiency: implications in degenerative and chronic diseases.
    Clinical science (London, England : 1979), 2015, Volume: 129, Issue:12

    Topics: Animals; Cardiovascular Diseases; Cation Transport Proteins; Chronic Disease; Humans; Imipramine; In

2015