imipramine has been researched along with Neuralgia in 15 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Monotherapy with first-line drugs for neuropathic pain often fails to provide sufficient pain relief or has unacceptable side effects because of the need for high doses." | 2.80 | Imipramine and pregabalin combination for painful polyneuropathy: a randomized controlled trial. ( Bach, FW; Brøsen, K; Finnerup, NB; Holbech, JV; Jensen, TS; Sindrup, SH, 2015) |
| "Other types of neuropathic pain include post-herpetic neuralgia, trigeminal neuralgia, and neuralgia caused by chemotherapy." | 2.52 | Venlafaxine for neuropathic pain in adults. ( Buggy, DJ; Butler, M; Gallagher, HC; Gallagher, RM; Henman, MC, 2015) |
| "The development of hind paw mechanical allodynia was measured after BCAO using the von Frey test." | 1.43 | Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia. ( Harada, S; Matsuura, W; Tokuyama, S, 2016) |
| "The effect of long-term administration of imipramine, a tricyclic antidepressant, on the phosphorylation status of cyclic adenosine monophosphate-responsive element-binding protein (CREB), mitogen-activated protein kinase family members, and phospholipase γ-1 (PLCγ-1) was investigated in the dorsal horn of the spinal cord following peripheral nerve lesion." | 1.39 | Long-term antidepressant treatment inhibits neuropathic pain-induced CREB and PLCγ-1 phosphorylation in the mouse spinal cord dorsal horn. ( Cadetti, F; Franciosi, A; Kusuda, R; Lucas, G; Previdelli, K; Ravanelli, MI; Zanon, S, 2013) |
| "Neuropathic pain is a serious chronic disorder caused by lesion or dysfunction in the nervous systems." | 1.36 | Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de ( Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K, 2010) |
| " A dosing strategy for the combbination of clomipramine and haloperidol is described." | 1.26 | [The treatment of chronic pain symptoms with psychotropic drugs (author's transl)]. ( Kocher, R, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, S | 1 |
| Nakata, E | 1 |
| Morita, A | 1 |
| Mizuno, K | 1 |
| Yamamura, K | 1 |
| Kato, A | 1 |
| Ohashi, K | 1 |
| Gillving, M | 1 |
| Demant, D | 2 |
| Holbech, JV | 3 |
| Gylfadottir, SS | 1 |
| Bach, FW | 5 |
| Jensen, TS | 5 |
| Finnerup, NB | 4 |
| Sindrup, SH | 5 |
| Holbech, J | 1 |
| Kusuda, R | 1 |
| Ravanelli, MI | 1 |
| Cadetti, F | 1 |
| Franciosi, A | 1 |
| Previdelli, K | 1 |
| Zanon, S | 1 |
| Lucas, G | 1 |
| Hearn, L | 1 |
| Derry, S | 1 |
| Phillips, T | 1 |
| Moore, RA | 1 |
| Wiffen, PJ | 1 |
| Brøsen, K | 2 |
| Gallagher, HC | 1 |
| Gallagher, RM | 1 |
| Butler, M | 1 |
| Buggy, DJ | 1 |
| Henman, MC | 1 |
| Matsuura, W | 1 |
| Harada, S | 1 |
| Tokuyama, S | 1 |
| Madsen, C | 1 |
| Gram, LF | 1 |
| WEBB, HE | 1 |
| LASCELLES, RG | 1 |
| Makise, H | 1 |
| Sasaki, K | 1 |
| Nishida, N | 1 |
| Igarashi, O | 1 |
| Kubota, M | 1 |
| Goto, Y | 1 |
| Kocher, R | 1 |
| Bianchetti, L | 1 |
| Lapalche, C | 1 |
2 reviews available for imipramine and Neuralgia
| Article | Year |
|---|---|
Imipramine for neuropathic pain in adults.
Topics: Adult; Analgesics; Antidepressive Agents, Tricyclic; Diabetic Neuropathies; Humans; Imipramine; Midd | 2014 |
Venlafaxine for neuropathic pain in adults.
Topics: Adult; Analgesics, Non-Narcotic; Antidepressive Agents, Second-Generation; Carbamazepine; Humans; Im | 2015 |
5 trials available for imipramine and Neuralgia
| Article | Year |
|---|---|
A randomized, controlled trial of a β2-agonist in painful polyneuropathy.
Topics: Antidepressive Agents, Tricyclic; Double-Blind Method; Humans; Imipramine; Neuralgia; Pain Measureme | 2021 |
Impact of etiology and duration of pain on pharmacological treatment effects in painful polyneuropathy.
Topics: Adult; Aged; Anticonvulsants; Antidepressive Agents; Carbamazepine; Diabetic Neuropathies; Female; H | 2017 |
Imipramine and pregabalin combination for painful polyneuropathy: a randomized controlled trial.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Analgesics; Cross-Over Studies; Dose-R | 2015 |
The Impact of Serum Drug Concentration on the Efficacy of Imipramine, Pregabalin, and their Combination in Painful Polyneuropathy.
Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Analgesics; Cross-Over Studies; Dose-R | 2017 |
Venlafaxine versus imipramine in painful polyneuropathy: a randomized, controlled trial.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Cross-Over Studies; Cyclohexanols; Diabetic Neuropathies; Dou | 2003 |
8 other studies available for imipramine and Neuralgia
| Article | Year |
|---|---|
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, | 2010 |
Long-term antidepressant treatment inhibits neuropathic pain-induced CREB and PLCγ-1 phosphorylation in the mouse spinal cord dorsal horn.
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Blotting, Wester | 2013 |
Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia.
Topics: Amines; Analgesics; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antico | 2016 |
Treatment of facial and head pain associated with depression.
Topics: Depression; Depressive Disorder; Face; Headache; Hydrazines; Imipramine; Neuralgia | 1962 |
[Statistical observations on patients with herpes zoster and postherpetic neuralgia (author's transl)].
Topics: Adolescent; Adult; Age Factors; Aged; Female; Herpes Zoster; Humans; Imipramine; Male; Middle Aged; | 1981 |
[The treatment of chronic pain symptoms with psychotropic drugs (author's transl)].
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bone Diseases; Clomipramine; Drug Therapy, C | 1976 |
[Drug therapy of so-called postherpetic neuralgia, the only valid alternative. Clinical experience in 43 treated cases].
Topics: Administration, Oral; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; D | 1986 |
[Antalgic effect of certain psychotropic drugs].
Topics: Anticonvulsants; Humans; Imipramine; Neuralgia; Neuritis; Pain | 1964 |