imipramine has been researched along with Neoplasms in 26 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
Excerpt | Relevance | Reference |
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"Fifty-two cancer patients diagnosed as having neuropathic pain were allocated into four groups: G400-I group took gabapentin 200 mg and imipramine 10 mg every 12 h orally; G400 group took gabapentin 200 mg every 12 h orally; G800 group took gabapentin 400 mg every 12 h orally; I group took imipramine 10 mg every 12 h orally." | 9.14 | Low-dose gabapentin as useful adjuvant to opioids for neuropathic cancer pain when combined with low-dose imipramine. ( Arai, YC; Arakawa, M; Hayashi, R; Kinoshita, A; Kobayashi, K; Kondo, M; Matsubara, S; Matsubara, T; Nishida, K; Nishihara, M; Shimo, K; Suetomi, K; Suzuki, C; Tohyama, Y; Ushida, T, 2010) |
"A prospective double-blind randomized trial was conducted on 184 cancer patients with moderate to severe chronic pain to evaluate the analgesic efficacy and tolerability of diclofenac alone (50 mg q." | 9.08 | Double-blind evaluation of short-term analgesic efficacy of orally administered diclofenac, diclofenac plus codeine, and diclofenac plus imipramine in chronic cancer pain. ( Celani, MG; De Angelis, V; Del Favero, A; Fumi, G; Lupatelli, M; Minotti, V; Monza, G; Pisati, R; Righetti, E; Rossetti, R; Tonato, M, 1998) |
"Burkitt lymphoma is a rare malignancy arising from B cells." | 5.40 | The NADPH oxidase inhibitor imipramine-blue in the treatment of Burkitt lymphoma. ( Becker, J; Eberth, S; Klingenberg, M; Kube, D; Wilting, J, 2014) |
"Fifty-two cancer patients diagnosed as having neuropathic pain were allocated into four groups: G400-I group took gabapentin 200 mg and imipramine 10 mg every 12 h orally; G400 group took gabapentin 200 mg every 12 h orally; G800 group took gabapentin 400 mg every 12 h orally; I group took imipramine 10 mg every 12 h orally." | 5.14 | Low-dose gabapentin as useful adjuvant to opioids for neuropathic cancer pain when combined with low-dose imipramine. ( Arai, YC; Arakawa, M; Hayashi, R; Kinoshita, A; Kobayashi, K; Kondo, M; Matsubara, S; Matsubara, T; Nishida, K; Nishihara, M; Shimo, K; Suetomi, K; Suzuki, C; Tohyama, Y; Ushida, T, 2010) |
"This study aimed to compare the effectiveness of mirtazapine and imipramine on not only the distressing symptoms of cancer patients such as pain, nausea, vomiting, appetite loss, and sleep disturbances but also depressive and anxiety symptoms." | 5.13 | Mirtazapine improves sleep and lowers anxiety and depression in cancer patients: superiority over imipramine. ( Akbiyik, DI; Alkis, N; Cankurtaran, ES; Ozalp, E; Soygur, H; Turhan, L, 2008) |
"A prospective double-blind randomized trial was conducted on 184 cancer patients with moderate to severe chronic pain to evaluate the analgesic efficacy and tolerability of diclofenac alone (50 mg q." | 5.08 | Double-blind evaluation of short-term analgesic efficacy of orally administered diclofenac, diclofenac plus codeine, and diclofenac plus imipramine in chronic cancer pain. ( Celani, MG; De Angelis, V; Del Favero, A; Fumi, G; Lupatelli, M; Minotti, V; Monza, G; Pisati, R; Righetti, E; Rossetti, R; Tonato, M, 1998) |
" In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
"Burkitt lymphoma is a rare malignancy arising from B cells." | 1.40 | The NADPH oxidase inhibitor imipramine-blue in the treatment of Burkitt lymphoma. ( Becker, J; Eberth, S; Klingenberg, M; Kube, D; Wilting, J, 2014) |
"Eight depressed children with cancer had a rapid clinical response to low doses of imipramine or amitriptyline." | 1.27 | Tricyclic antidepressants for children with cancer. ( Cangir, A; Choroszy, M; Kumor, K; Pfefferbaum-Levine, B; Roseberry, EA, 1983) |
" A dosing strategy for the combbination of clomipramine and haloperidol is described." | 1.26 | [The treatment of chronic pain symptoms with psychotropic drugs (author's transl)]. ( Kocher, R, 1976) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 18 (69.23) | 18.7374 |
1990's | 1 (3.85) | 18.2507 |
2000's | 2 (7.69) | 29.6817 |
2010's | 5 (19.23) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Tukey, RH | 1 |
Strassburg, CP | 1 |
Dolusić, E | 1 |
Larrieu, P | 1 |
Moineaux, L | 1 |
Stroobant, V | 1 |
Pilotte, L | 1 |
Colau, D | 1 |
Pochet, L | 1 |
Van den Eynde, B | 1 |
Masereel, B | 1 |
Wouters, J | 1 |
Frédérick, R | 1 |
Unzue, A | 1 |
Lafleur, K | 1 |
Zhao, H | 1 |
Zhou, T | 1 |
Dong, J | 1 |
Kolb, P | 1 |
Liebl, J | 1 |
Zahler, S | 1 |
Caflisch, A | 1 |
Nevado, C | 1 |
Service, RF | 1 |
Klingenberg, M | 1 |
Becker, J | 1 |
Eberth, S | 1 |
Kube, D | 1 |
Wilting, J | 1 |
Arai, YC | 1 |
Matsubara, T | 1 |
Shimo, K | 1 |
Suetomi, K | 1 |
Nishihara, M | 1 |
Ushida, T | 1 |
Kobayashi, K | 1 |
Suzuki, C | 1 |
Kinoshita, A | 1 |
Kondo, M | 1 |
Matsubara, S | 1 |
Hayashi, R | 1 |
Tohyama, Y | 1 |
Nishida, K | 1 |
Arakawa, M | 1 |
HUGUES, A | 2 |
CHAUVERGNE, J | 2 |
LISSILOUR, J | 1 |
LAGARDE, C | 2 |
KRAMER, M | 1 |
LACHAPELE, A | 1 |
DAY, M | 1 |
STOCKBRIDGE, A | 1 |
STENDARDO, B | 1 |
Cankurtaran, ES | 1 |
Ozalp, E | 1 |
Soygur, H | 1 |
Akbiyik, DI | 1 |
Turhan, L | 1 |
Alkis, N | 1 |
Pfefferbaum-Levine, B | 1 |
Kumor, K | 1 |
Cangir, A | 1 |
Choroszy, M | 1 |
Roseberry, EA | 1 |
Ziebarth, D | 1 |
Schulz, P | 1 |
Luttrell, S | 1 |
Minotti, V | 1 |
De Angelis, V | 1 |
Righetti, E | 1 |
Celani, MG | 1 |
Rossetti, R | 1 |
Lupatelli, M | 1 |
Tonato, M | 1 |
Pisati, R | 1 |
Monza, G | 1 |
Fumi, G | 1 |
Del Favero, A | 1 |
Kocher, R | 2 |
Purohit, DR | 1 |
Navlakha, PL | 1 |
Modi, RS | 1 |
Eshpumiyani, R | 1 |
Evans, DL | 1 |
McCartney, CF | 1 |
Nemeroff, CB | 1 |
Haggerty, JJ | 1 |
Simon, JS | 1 |
Pedersen, CA | 1 |
Holmes, V | 1 |
Droba, M | 1 |
Mason, GA | 1 |
Raft, D | 1 |
Deutschmann, W | 1 |
Buttaro, CA | 1 |
Silvestri, D | 1 |
Turchetti, A | 1 |
Rohrer, G | 1 |
Miliani, P | 1 |
Viallet, M | 1 |
Viallet, JF | 1 |
Isnard, A | 1 |
Lapalus, B | 1 |
Gimbergues, H | 1 |
Adjan, M | 1 |
Bortz, W | 1 |
3 reviews available for imipramine and Neoplasms
Article | Year |
---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
Three stories on Eph kinase inhibitors: From in silico discovery to in vivo validation.
Topics: Animals; Computer Simulation; Drug Design; Humans; Isoquinolines; Neoplasms; Protein Kinase Inhibito | 2016 |
Depression in cancer patients. Diagnostic and treatment considerations.
Topics: Depressive Disorder; Dexamethasone; Female; Genital Neoplasms, Female; Imipramine; Neoplasms; Pilot | 1988 |
4 trials available for imipramine and Neoplasms
Article | Year |
---|---|
Low-dose gabapentin as useful adjuvant to opioids for neuropathic cancer pain when combined with low-dose imipramine.
Topics: Aged; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; | 2010 |
Mirtazapine improves sleep and lowers anxiety and depression in cancer patients: superiority over imipramine.
Topics: Adaptation, Psychological; Adjustment Disorders; Adrenergic alpha-Antagonists; Adult; Antidepressive | 2008 |
Double-blind evaluation of short-term analgesic efficacy of orally administered diclofenac, diclofenac plus codeine, and diclofenac plus imipramine in chronic cancer pain.
Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anti | 1998 |
[Treatment of severe chronic pains with a combination of thymoleptics and neuroleptics (author's transl)].
Topics: Adult; Antidepressive Agents; Atropine; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Drug | 1974 |
19 other studies available for imipramine and Neoplasms
Article | Year |
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Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.
Topics: Animals; Antineoplastic Agents; Biological Availability; Cell Line; Drug Design; Enzyme Inhibitors; | 2011 |
Biology's dry future.
Topics: Access to Information; Antidepressive Agents; Data Mining; Databases, Genetic; Disease; Genome, Huma | 2013 |
The NADPH oxidase inhibitor imipramine-blue in the treatment of Burkitt lymphoma.
Topics: Animals; Antineoplastic Agents; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Cell Surviva | 2014 |
[Imipramine used as major analgesic in carcinology. Study of 118 cases].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Humans; Imipramine; Neoplasms | 1963 |
DELIRIUM AS A COMPLICATION OF IMIPRAMINE THERAPY IN THE AGED.
Topics: Astrocytoma; Brain Neoplasms; Delirium; Geriatrics; Imipramine; Neoplasms; Temporal Lobe; Toxicology | 1963 |
[NEW MAJOR ANALGESICS IN CARCINOLOGY].
Topics: Analgesics; Antidepressive Agents; Humans; Imipramine; Neoplasms; Palliative Care | 1964 |
THE EFFECTS OF DRUGS ON THE UPTAKE OF AMINES BY MAST CELLS.
Topics: Amines; Animals; Chlorpromazine; Cocaine; Ethanolamines; Guanethidine; Hallucinogens; Histamine; Imi | 1964 |
[ON ANTALGIC PROPERTIES OF IMIPRAMINE IN ONCOLOGY].
Topics: Imipramine; Internal Medicine; Neoplasms; Toxicology | 1964 |
Tricyclic antidepressants for children with cancer.
Topics: Adolescent; Amitriptyline; Child; Child, Preschool; Depressive Disorder; Female; Humans; Imipramine; | 1983 |
[Comparative studies of the nitrosation behavior of drugs by constant pH value and under simulated stomach conditions].
Topics: Aminopyrine; Ampicillin; Biotransformation; Clomipramine; Desipramine; Dipyrone; Ethambutol; Gastric | 1982 |
Increased plasma protein binding of imipramine in cancer patients.
Topics: Adult; Aged; Erythrocytes; Female; Humans; Imipramine; Male; Middle Aged; Neoplasms; Protein Binding | 1982 |
[The treatment of chronic pain symptoms with psychotropic drugs (author's transl)].
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bone Diseases; Clomipramine; Drug Therapy, C | 1976 |
The role antidepressants in hospitalised cancer patients. (A pilot study).
Topics: Adult; Depression; Female; Humans; Imipramine; Male; Middle Aged; Neoplasms | 1978 |
[Tofranil in pain therapy of cancer patients].
Topics: Humans; Imipramine; Neoplasms; Pain; Palliative Care | 1971 |
[On the antalgic action of imipramine in oncology].
Topics: Humans; Imipramine; Neoplasms; Palliative Care | 1970 |
[Use of tofranil as antalgic in surgery].
Topics: Aged; Analgesics; Female; Humans; Imipramine; Male; Middle Aged; Neoplasms; Postoperative Care; Preo | 1969 |
[Value of a thymoleptic agent combined with local therapy in practical carcinology].
Topics: Humans; Imipramine; Mental Disorders; Neoplasms; Skin Neoplasms | 1969 |
[Therapeutic influence of pain symptoms in incurable tumor patients].
Topics: Humans; Imipramine; Neoplasms; Pain | 1970 |
[Treatment of severe pain in patients with carcinoma].
Topics: Humans; Imipramine; Neoplasms; Pain | 1967 |