imipramine has been researched along with Necrosis in 6 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Four anticalmodulin drugs: trifluoperazine (TFP), pimozide (PMZ), thioridazine (TDZ) and imipramine (IMP) (50 mg/kg, ip) were able to partially prevent Galactosamine (GAL) (600 mg/kg, ip) induced liver necrosis when given 6 h after the hepatotoxin." | 7.67 | Late preventive effects of several anticalmodulin drugs on galactosamine-induced liver necrosis. ( Castro, JA; de Fenos, OM; de Ferreyra, EC, 1985) |
| "Four anticalmodulin drugs: trifluoperazine (TFP), pimozide (PMZ), thioridazine (TDZ) and imipramine (IMP) (50 mg/kg, ip) were able to partially prevent Galactosamine (GAL) (600 mg/kg, ip) induced liver necrosis when given 6 h after the hepatotoxin." | 3.67 | Late preventive effects of several anticalmodulin drugs on galactosamine-induced liver necrosis. ( Castro, JA; de Fenos, OM; de Ferreyra, EC, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fernández, G | 1 |
| Villarruel, MC | 1 |
| de Ferreyra, EC | 2 |
| de Fenos, OM | 2 |
| Castro, JA | 3 |
| Powell, WJ | 1 |
| Koch-Weser, J | 1 |
| Williams, RA | 1 |
| Wrights, N | 1 |
| Prescott, LF | 1 |
| Cignoli, EV | 1 |
| Linton, AL | 1 |
| Adams, JH | 1 |
| Lawson, DH | 1 |
6 other studies available for imipramine and Necrosis
| Article | Year |
|---|---|
Imipramine prevention of carbon tetrachloride-induced liver necrosis at late states of the intoxication process.
Topics: Animals; Body Temperature; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; C | 1986 |
Late preventive effects of several anticalmodulin drugs on galactosamine-induced liver necrosis.
Topics: Animals; Calmodulin; Galactosamine; Imipramine; Liver; Male; Necrosis; Pimozide; Rats; Thioridazine; | 1985 |
Lethal hepatic necrosis after therapy with imipramine and desipramine.
Topics: Aged; Chemical and Drug Induced Liver Injury; Dermatitis, Exfoliative; Desipramine; Drug Hypersensit | 1968 |
Potentiation by previous drug therapy of hepatotoxicity following paracetamol overdosage.
Topics: Acetaminophen; Adolescent; Adult; Amobarbital; Aspartate Aminotransferases; Bilirubin; Chemical and | 1973 |
Effect of inhibitors of drug metabolizing enzymes on carbon tetrachloride hepatotoxicity.
Topics: Aminopyrine; Animals; Biotransformation; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemi | 1971 |
Muscle necrosis and acute renal failure in carbon monoxide poisoning.
Topics: Acute Kidney Injury; Adult; Amobarbital; Carbon Monoxide Poisoning; Female; Humans; Imipramine; Musc | 1968 |