imipramine has been researched along with Myocardial Ischemia in 2 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Medical treatment of heart failure is associated with 50% survival at 5 years." | 2.43 | Animal models of heart failure: what is new? ( Chachques, JC; Monnet, E, 2005) |
| "Cardiac ischemia and anoxia induce massive norepinephrine (NE) release, which is mediated by a reverse operation of uptake-1 and can be suppressed by uptake-1 inhibitors." | 1.30 | Protection of neuronal uptake-1 inhibitors in ischemic and anoxic hearts by norepinephrine-dependent and -independent mechanisms. ( Dart, AM; Du, XJ; Esler, MD; Little, PJ; Woodcock, EA, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Monnet, E | 1 |
| Chachques, JC | 1 |
| Du, XJ | 1 |
| Woodcock, EA | 1 |
| Little, PJ | 1 |
| Esler, MD | 1 |
| Dart, AM | 1 |
1 review available for imipramine and Myocardial Ischemia
| Article | Year |
|---|---|
Animal models of heart failure: what is new?
Topics: Animals; Blood Pressure; Cardiac Volume; Cardiomyopathy, Dilated; Disease Models, Animal; Doxorubici | 2005 |
1 other study available for imipramine and Myocardial Ischemia
| Article | Year |
|---|---|
Protection of neuronal uptake-1 inhibitors in ischemic and anoxic hearts by norepinephrine-dependent and -independent mechanisms.
Topics: Adrenergic Uptake Inhibitors; Animals; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Drug Intera | 1998 |