imipramine has been researched along with Myocardial Infarction in 13 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
| Excerpt | Relevance | Reference |
|---|---|---|
| " During a double-blind drug and dose selection phase, investigators were permitted to change drug or dosage to achieve greater than or equal to 70% suppression in VPC frequency and greater than 90% suppression of runs of VPC with the exception of patients assigned to placebo, who continued receiving it." | 6.66 | Effects of encainide, flecainide, imipramine and moricizine on ventricular arrhythmias during the year after acute myocardial infarction: the CAPS. ( , 1988) |
| "The relationship between binding ratio of imipramine and plasma alpha 1-acid glycoprotein (AAG) was determined in normal subjects, patients with chest pain syndrome, and patients after myocardial infarction." | 3.67 | Imipramine binding to alpha-1-acid glycoprotein in normal subjects and cardiac patients. ( Freilich, DI; Giardina, EG, 1984) |
| "The authors report on 12 men with ischemic heart disease who developed secondary depression following myocardial infarction or coronary artery bypass-graft surgery and were treated with imipramine hydrochloride for 4 weeks." | 3.66 | Cardiovascular and antidepressant effects of imipramine in the treatment of secondary depression in patients with ischemic heart disease. ( Barnes, R; Gumbrecht, G; Raskind, M; Veith, R, 1982) |
| " In 1 patient, acute myocardial infarction developed after two 10-mg doses of nortriptyline." | 3.66 | Cardiovascular side effects of long-term therapy with tricyclic antidepressants in the aged. ( Oei, LS; Rodstein, M, 1979) |
| " During a double-blind drug and dose selection phase, investigators were permitted to change drug or dosage to achieve greater than or equal to 70% suppression in VPC frequency and greater than 90% suppression of runs of VPC with the exception of patients assigned to placebo, who continued receiving it." | 2.66 | Effects of encainide, flecainide, imipramine and moricizine on ventricular arrhythmias during the year after acute myocardial infarction: the CAPS. ( , 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SLOMAN, L | 1 |
| Raskind, M | 1 |
| Veith, R | 1 |
| Barnes, R | 1 |
| Gumbrecht, G | 1 |
| Freilich, DI | 1 |
| Giardina, EG | 1 |
| McNeil, GN | 1 |
| Shaw, PK | 1 |
| Dock, DS | 1 |
| Rodstein, M | 1 |
| Oei, LS | 1 |
| Greene, HL | 1 |
| Richardson, DW | 1 |
| Hallstrom, AP | 2 |
| McBride, R | 1 |
| Capone, RJ | 1 |
| Barker, AH | 2 |
| Roden, DM | 1 |
| Echt, DS | 1 |
| Anderson, JL | 1 |
| Griffith, LS | 1 |
| Ledingham, RB | 1 |
| Reiffel, JA | 1 |
| Yusuf, S | 1 |
| Fowles, RE | 1 |
| Young, JB | 1 |
| Wood, M | 1 |
| Moccetti, T | 2 |
| Lichtlen, P | 1 |
| Goldstein, RL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000504] | Phase 2 | 0 participants | Interventional | 1982-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for imipramine and Myocardial Infarction
| Article | Year |
|---|---|
Plasma drug binding: implications for anesthesiologists.
Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Ca | 1986 |
4 trials available for imipramine and Myocardial Infarction
| Article | Year |
|---|---|
Recruitment and baseline description of patients in the Cardiac Arrhythmia Pilot Study. The Cardiac Arrhythmia Pilot Study (CAPS) investigators.
Topics: Anilides; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Electrocardiography; Encainide; Feas | 1988 |
Congestive heart failure after acute myocardial infarction in patients receiving antiarrhythmic agents for ventricular premature complexes (Cardiac Arrhythmia Pilot Study).
Topics: Anilides; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Double-Blind Method; Encainide; Fema | 1989 |
Relation of baseline characteristics to suppression of ventricular arrhythmias during placebo and active antiarrhythmic therapy in patients after myocardial infarction.
Topics: Anilides; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Encainide; Flecainide; Humans; Imipr | 1989 |
Effects of encainide, flecainide, imipramine and moricizine on ventricular arrhythmias during the year after acute myocardial infarction: the CAPS.
Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Metho | 1988 |
8 other studies available for imipramine and Myocardial Infarction
| Article | Year |
|---|---|
Myocardial infarction during imipramine treatment of depression.
Topics: Cardiovascular Diseases; Depression; Depressive Disorder; Humans; Imipramine; Myocardial Infarction; | 1960 |
Cardiovascular and antidepressant effects of imipramine in the treatment of secondary depression in patients with ischemic heart disease.
Topics: Adult; Aged; Blood Pressure; Cardiac Complexes, Premature; Coronary Artery Bypass; Coronary Disease; | 1982 |
Imipramine binding to alpha-1-acid glycoprotein in normal subjects and cardiac patients.
Topics: Adult; Aged; Humans; Imipramine; Middle Aged; Myocardial Infarction; Orosomucoid; Pain; Protein Bind | 1984 |
Substitution of atenolol for propranolol in a case of propranolol-related depression.
Topics: Angina Pectoris; Atenolol; Depressive Disorder; Female; Humans; Hypertension; Imipramine; Middle Age | 1982 |
Cardiovascular side effects of long-term therapy with tricyclic antidepressants in the aged.
Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular System; | 1979 |
[Cardiotoxic drugs].
Topics: Adult; Angina Pectoris; Anti-Bacterial Agents; Antipsychotic Agents; Chloroquine; Contraceptives, Or | 1973 |
[Changes in the heart due to phenothiazines and imipramine derivatives].
Topics: Aged; Anticonvulsants; Arrhythmias, Cardiac; Death, Sudden; Electrocardiography; Heart Diseases; Hea | 1971 |
Fatal myocardial infarction associated with sub-clinical doses of imipramine.
Topics: Depression; Humans; Imipramine; Male; Middle Aged; Myocardial Infarction | 1969 |