imipramine and Muscular Dystrophies studies

imipramine and Muscular Dystrophies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Muscular Dystrophies: A heterogeneous group of inherited MYOPATHIES, characterized by wasting and weakness of the SKELETAL MUSCLE. They are categorized by the sites of MUSCLE WEAKNESS; AGE OF ONSET; and INHERITANCE PATTERNS.

Research Excerpts

Excerpt	Relevance	Reference
"Administration of imipramine plus serotonin (5-HT) to rats has been proposed as an animal model of Duchenne muscular dystrophy."	3.65	Skeletal muscle necrosis following membrane-active drugs plus serotonin. ( Meltzer, HY, 1976)

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	5 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

5 (100.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Brumback, RA	1
Carlson, KM	1
Meltzer, HY	2
Munsat, TL	1
Hudgson, P	1
Johnson, MA	1
Stahl, SM	1
Parker, JM	1
Mendell, JR	1

Studies

Brumback, RA

Carlson, KM

Meltzer, HY

Munsat, TL

Hudgson, P

Johnson, MA

Stahl, SM

Parker, JM

Mendell, JR

Other Studies

5 other studies available for imipramine and Muscular Dystrophies

Article	Year
The depression of myotonic dystrophy: response to imipramine. Journal of neurology, neurosurgery, and psychiatry, 1983, Volume: 46, Issue:6 Topics: Adult; Depressive Disorder; Female; Humans; Imipramine; Male; Middle Aged; Muscular Dystrophies	1983
Skeletal muscle necrosis following membrane-active drugs plus serotonin. Journal of the neurological sciences, 1976, Volume: 28, Issue:1 Topics: Animals; Antidepressive Agents, Tricyclic; Disease Models, Animal; Drug Synergism; Histamine H1 Anta	1976
Experimental serotonin myopathy. Neurology, 1977, Volume: 27, Issue:8 Topics: Animals; Capillaries; Disease Models, Animal; Imipramine; Male; Muscles; Muscular Diseases; Muscular	1977
Serotonin accumulation by skeletal muscle. Experimental neurology, 1977, Volume: 54, Issue:1 Topics: Animals; Biological Transport; Chlorpheniramine; Chlorpromazine; Clomipramine; Dose-Response Relatio	1977
Proximal myopathy induced by 5-HT-imipramine simulates Duchenne dystrophy. Nature, 1974, Jan-11, Volume: 247, Issue:5436 Topics: Animals; Disease Models, Animal; Imipramine; Male; Muscular Dystrophies; Rats; Serotonin	1974

Article

Year

The depression of myotonic dystrophy: response to imipramine.

Journal of neurology, neurosurgery, and psychiatry, 1983, Volume: 46, Issue:6

Topics: Adult; Depressive Disorder; Female; Humans; Imipramine; Male; Middle Aged; Muscular Dystrophies

1983

Skeletal muscle necrosis following membrane-active drugs plus serotonin.

Journal of the neurological sciences, 1976, Volume: 28, Issue:1

Topics: Animals; Antidepressive Agents, Tricyclic; Disease Models, Animal; Drug Synergism; Histamine H1 Anta

1976

Experimental serotonin myopathy.

Neurology, 1977, Volume: 27, Issue:8

Topics: Animals; Capillaries; Disease Models, Animal; Imipramine; Male; Muscles; Muscular Diseases; Muscular

1977

Serotonin accumulation by skeletal muscle.

Experimental neurology, 1977, Volume: 54, Issue:1

Topics: Animals; Biological Transport; Chlorpheniramine; Chlorpromazine; Clomipramine; Dose-Response Relatio

1977

Proximal myopathy induced by 5-HT-imipramine simulates Duchenne dystrophy.

Nature, 1974, Jan-11, Volume: 247, Issue:5436

Topics: Animals; Disease Models, Animal; Imipramine; Male; Muscular Dystrophies; Rats; Serotonin

1974