imipramine has been researched along with Muscle Rigidity in 4 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with Parkinson's syndrome whose major symptoms are akinesis, rigidity, inertia, depression, irritability and failure of adaptation rather than tremor appear to benefit in a global way from therapy with imipramine." | 7.64 | Parkinson's syndrome, depression and imipramine. A preliminary report. ( FOWLER, W; MANDELL, AJ; MARKHAM, C, 1961) |
| "Patients with Parkinson's syndrome whose major symptoms are akinesis, rigidity, inertia, depression, irritability and failure of adaptation rather than tremor appear to benefit in a global way from therapy with imipramine." | 3.64 | Parkinson's syndrome, depression and imipramine. A preliminary report. ( FOWLER, W; MANDELL, AJ; MARKHAM, C, 1961) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MANDELL, AJ | 1 |
| MARKHAM, C | 1 |
| FOWLER, W | 1 |
| Sell, SL | 1 |
| McMahon, LR | 1 |
| Koek, W | 1 |
| France, CP | 1 |
| Lisciani, R | 1 |
| Baldini, A | 1 |
| Ciottoli, GB | 1 |
| Schulterbrandt, JG | 1 |
| Raskin, A | 1 |
| Reatig, N | 1 |
1 trial available for imipramine and Muscle Rigidity
| Article | Year |
|---|---|
True and apparent side effects in a controlled trial of chlorpromazine and imipramine in depression.
Topics: Adult; Agranulocytosis; Chlorpromazine; Clinical Trials as Topic; Depression; Dermatitis; Edema; Eva | 1974 |
3 other studies available for imipramine and Muscle Rigidity
| Article | Year |
|---|---|
Parkinson's syndrome, depression and imipramine. A preliminary report.
Topics: Depression; Depressive Disorder; Humans; Imipramine; Irritable Mood; Motivation; Muscle Rigidity; Pa | 1961 |
Monoaminergic drugs and directly observable signs of LAAM withdrawal in rhesus monkeys.
Topics: Adrenergic alpha-Agonists; Amphetamine; Analgesics, Opioid; Animals; Antidepressive Agents, Tricycli | 2005 |
Behavioral study on the interactions between trazodone and L-dopa.
Topics: Animals; Behavior, Animal; Drug Interactions; Female; Haloperidol; Imipramine; Levodopa; Male; Mice; | 1979 |