imipramine has been researched along with Mood Disorders in 27 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Mood Disorders: Those disorders that have a disturbance in mood as their predominant feature.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Between Sept 11, 2005, and Aug 20, 2010, 107 patients with treatment-refractory functional dyspepsia were randomly assigned to receive imipramine (n=55) or placebo (n=52)." | 9.27 | Low-dose imipramine for refractory functional dyspepsia: a randomised, double-blind, placebo-controlled trial. ( Chan, FKL; Chan, Y; Cheong, PK; Cheung, CKY; Ching, JYL; Ford, AC; Sung, JJY; Wu, JCY, 2018) |
| "Between Sept 11, 2005, and Aug 20, 2010, 107 patients with treatment-refractory functional dyspepsia were randomly assigned to receive imipramine (n=55) or placebo (n=52)." | 5.27 | Low-dose imipramine for refractory functional dyspepsia: a randomised, double-blind, placebo-controlled trial. ( Chan, FKL; Chan, Y; Cheong, PK; Cheung, CKY; Ching, JYL; Ford, AC; Sung, JJY; Wu, JCY, 2018) |
| " Here, sucrose intake, forced swimming, immobility in the modified tail suspension test, novelty exploration, grooming, anxiety and locomotor activity were compared in naïve 3- and 18-month-old male C57BL/6 mice." | 3.78 | Anhedonic-like traits and lack of affective deficits in 18-month-old C57BL/6 mice: Implications for modeling elderly depression. ( Bachurin, S; Bolkunov, A; Kubatiev, A; Malatynska, E; Redkozubova, O; Steinbusch, HW; Strekalova, T; Vignisse, J; Yeritsyan, NB, 2012) |
| "Imipramine was associated with a significantly reduced frequency of binge eating and with improvement on several other measures of eating behavior." | 2.65 | Bulimia treated with imipramine: a placebo-controlled, double-blind study. ( Hudson, JI; Jonas, JM; Pope, HG; Yurgelun-Todd, D, 1983) |
| " Chronic administration of imipramine tended to attenuate the impairment of SI behavior in stressed mice, but not significantly." | 1.35 | Effects of (R)-(-)-1-(benzofuran-2-yl)-2-propylaminopentane hydrochloride [(-)-BPAP] in animal models of mood disorders. ( Miyazaki, M; Nabeshima, T; Noda, Y; Tsunekawa, H; Wang, D; Yoneda, F, 2008) |
| "Mood disorders are the leading causes of morbidity and mortality in children and adolescence." | 1.31 | Mood disorders in children and adolescents: psychopharmacological treatment. ( Emslie, GJ; Mayes, TL, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (74.07) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 3 (11.11) | 29.6817 |
| 2010's | 2 (7.41) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Reddy, BR | 1 |
| Babu, NS | 1 |
| Das, T | 1 |
| Bhattacharya, D | 1 |
| Murthy, CLN | 1 |
| Kumar, A | 1 |
| Idris, MM | 1 |
| Chakravarty, S | 1 |
| Cheong, PK | 1 |
| Ford, AC | 1 |
| Cheung, CKY | 1 |
| Ching, JYL | 1 |
| Chan, Y | 1 |
| Sung, JJY | 1 |
| Chan, FKL | 1 |
| Wu, JCY | 1 |
| Malatynska, E | 1 |
| Steinbusch, HW | 1 |
| Redkozubova, O | 1 |
| Bolkunov, A | 1 |
| Kubatiev, A | 1 |
| Yeritsyan, NB | 1 |
| Vignisse, J | 1 |
| Bachurin, S | 1 |
| Strekalova, T | 1 |
| SCHOU, M | 1 |
| OLTMAN, JE | 1 |
| FRIEDMAN, S | 1 |
| Pokorny, AD | 1 |
| Prien, RF | 1 |
| Tsunekawa, H | 1 |
| Noda, Y | 1 |
| Miyazaki, M | 1 |
| Yoneda, F | 1 |
| Nabeshima, T | 1 |
| Wang, D | 1 |
| Costa, E | 1 |
| Elliott, JM | 1 |
| Goodwin, FK | 1 |
| Post, RM | 2 |
| Berrettini, WH | 2 |
| Goldin, LR | 1 |
| Nurnberger, JI | 1 |
| Gershon, ES | 1 |
| Pope, HG | 1 |
| Hudson, JI | 1 |
| Jonas, JM | 1 |
| Yurgelun-Todd, D | 1 |
| Sternberg, DE | 1 |
| Johnson-Sabine, E | 1 |
| Markovskaia, NS | 1 |
| Zurabian, NK | 1 |
| Rymsha, AK | 1 |
| Zvolsky, P | 1 |
| Jansky, L | 1 |
| Vyskocilova, J | 1 |
| Grof, P | 1 |
| Langer, SZ | 1 |
| Zarifian, E | 1 |
| Briley, M | 1 |
| Raisman, R | 1 |
| Sechter, D | 1 |
| Furukawa, T | 1 |
| Awaji, R | 1 |
| Nakazato, H | 1 |
| Sumita, Y | 1 |
| Emslie, GJ | 1 |
| Mayes, TL | 1 |
| de Kemp, EC | 1 |
| Moleman, P | 1 |
| Hoogduin, CA | 1 |
| Broekman, TG | 1 |
| Goedhart, A | 1 |
| Schaap, CP | 1 |
| van den Berg, PC | 1 |
| Kinzie, JD | 1 |
| Leung, P | 1 |
| Horodnicki, JM | 1 |
| Szakowski, A | 1 |
| Wdowiak, J | 1 |
| Mesones, HL | 1 |
| Cia, FM | 1 |
| Suzdak, PD | 1 |
| Gianutsos, G | 1 |
| Telner, J | 1 |
| Surphlis, W | 1 |
| Lapierre, Y | 1 |
| Mehta, G | 1 |
| Baron, M | 1 |
| Barkai, A | 1 |
| Gruen, R | 1 |
| Peselow, E | 1 |
| Fieve, RR | 1 |
| Quitkin, F | 1 |
| Uhde, TW | 1 |
| Roy-Byrne, PP | 1 |
| Boulenger, JP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Efficacy of Imipramine in Treatment of Functional Dyspepsia: A Double Blind Randomized Placebo Controlled Trial[NCT00164775] | Phase 3 | 107 participants (Actual) | Interventional | 2005-06-30 | Completed | ||
| Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD) a Multicentre Open-label Randomized Controlled Trial Protocol[NCT05814640] | Phase 1/Phase 2 | 520 participants (Anticipated) | Interventional | 2023-02-20 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for imipramine and Mood Disorders
| Article | Year |
|---|---|
Platelet receptor binding studies in affective disorders.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Blood Plate | 1984 |
Genetic factors in affective illness.
Topics: ABO Blood-Group System; Blood Platelets; Cholinergic Fibers; Diseases in Twins; Female; gamma-Aminob | 1984 |
Biologic tests in psychiatry.
Topics: Anxiety Disorders; Apomorphine; Clonidine; Dexamethasone; Dextroamphetamine; Growth Hormone; Humans; | 1984 |
6 trials available for imipramine and Mood Disorders
| Article | Year |
|---|---|
Low-dose imipramine for refractory functional dyspepsia: a randomised, double-blind, placebo-controlled trial.
Topics: Adult; Antidepressive Agents, Tricyclic; Double-Blind Method; Dyspepsia; Female; Gastrointestinal Ag | 2018 |
Lithium in treatment and prevention of affective disorder. A VA-NIMH collaborative study.
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bipolar Disorder; Chlorpromazine; Depressive | 1974 |
Bulimia treated with imipramine: a placebo-controlled, double-blind study.
Topics: Adolescent; Adult; Antidepressive Agents; Clinical Trials as Topic; Double-Blind Method; Feeding and | 1983 |
Persistence of chronic mood disorders: a 2 year follow-up.
Topics: Adult; Antidepressive Agents; Chronic Disease; Cohort Studies; Combined Modality Therapy; Diazepam; | 1995 |
Diagnosis at the first episode to differentiate antidepressant treatment responses in patients with mood and anxiety disorders.
Topics: Adult; Aged; Antidepressive Agents; Antidepressive Agents, Tricyclic; Anxiety Disorders; Diagnosis, | 2002 |
Effects of antidepressants on thinking styles in depressed inpatients.
Topics: Adult; Antidepressive Agents; Clinical Trials as Topic; Cognition; Female; Fluoxetine; Humans; Imipr | 1988 |
18 other studies available for imipramine and Mood Disorders
| Article | Year |
|---|---|
Proteome profile of telencephalon associates attenuated neurogenesis with chronic stress induced mood disorder phenotypes in zebrafish model.
Topics: Affect; Animals; Antidepressive Agents; Anxiety; Cell Proliferation; Depression; Disease Models, Ani | 2021 |
Anhedonic-like traits and lack of affective deficits in 18-month-old C57BL/6 mice: Implications for modeling elderly depression.
Topics: Aging; Anhedonia; Animals; Antidepressive Agents, Tricyclic; Anxiety; Behavior, Animal; Depressive D | 2012 |
NORMOTHYMOTICS, "MOOD-NORMALIZERS": ARE LITHIUM AND THE IMIPRAMINE DRUGS SPECIFIC FOR AFFECTIVE DISORDERS?
Topics: Antipsychotic Agents; Bipolar Disorder; Depression; Depressive Disorder; Electrocardiography; Emotio | 1963 |
Elavil in the treatment of affective disorders (and comparison with tofranil).
Topics: Amitriptyline; Depression; Depressive Disorder; Imipramine; Mood Disorders; Psychopharmacology | 1961 |
Effects of (R)-(-)-1-(benzofuran-2-yl)-2-propylaminopentane hydrochloride [(-)-BPAP] in animal models of mood disorders.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Antidepressive Agents; Behavior, Animal; Benzof | 2008 |
Perspectives in the molecular mechanisms of antidepressant action.
Topics: Animals; Antidepressive Agents; Humans; Imipramine; Mianserin; Mood Disorders; Neurotransmitter Agen | 1982 |
5-hydroxytryptamine and depression: a model for the interaction of normal variance with pathology.
Topics: Aggression; Animals; Autopsy; Biogenic Amines; Depressive Disorder; Humans; Hydroxyindoleacetic Acid | 1983 |
Bulimia associated with dysphoria rather than with affective disorder.
Topics: Affective Symptoms; Feeding and Eating Disorders; Humans; Hyperphagia; Imipramine; Mianserin; Mood D | 1983 |
[Effect of melipramine on affective states in alcoholism].
Topics: Adult; Affect; Humans; Imipramine; Male; Middle Aged; Mood Disorders; Psychopathology; Psychoses, Al | 1982 |
Effects of psychotropic drugs on hamster hibernation-pilot study.
Topics: Animals; Cricetinae; Hibernation; Humans; Imipramine; Lithium; Mesocricetus; Mood Disorders; Pilot P | 1981 |
High-affinity binding of 3H-imipramine in brain and platelets and its relevance to the biochemistry of affective disorders.
Topics: Animals; Binding Sites; Blood Platelets; Brain; Depression; Humans; Imipramine; Mood Disorders | 1981 |
Mood disorders in children and adolescents: psychopharmacological treatment.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Child; Depressive Disorder, Major; Drug Therapy, Combi | 2001 |
Clonidine in Cambodian patients with posttraumatic stress disorder.
Topics: Adult; Cambodia; Clonidine; Depressive Disorder; Drug Combinations; Female; Humans; Imipramine; Male | 1989 |
Influence of imipramine and amitriptyline on the hypothalamic function in affective disorders.
Topics: Adult; Amitriptyline; Dexamethasone; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; | 1989 |
[Correlation between clinical and laboratory data in depression. Therapeutic orientation by means of vitamins and amino acids].
Topics: Adjustment Disorders; Adolescent; Adult; Aged; Aniline Compounds; Antidepressive Agents; Catecholami | 1985 |
Parallel changes in the sensitivity of gamma-aminobutyric acid and noradrenergic receptors following chronic administration of antidepressant and GABAergic drugs. A possible role in affective disorders.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Baclofen; Cerebral Cortex; Dihydroalprenolol; gamma | 1985 |
Platelet 3H-imipramine binding and familial transmission of affective disorders.
Topics: Adult; Aged; Aged, 80 and over; Binding Sites; Blood Platelets; Female; Humans; Imipramine; Kinetics | 1987 |
Platelet [3H]imipramine binding in patients with panic disorder.
Topics: Adult; Blood Platelets; Fear; Female; Humans; Imipramine; Kinetics; Male; Middle Aged; Mood Disorder | 1987 |