Compounds > imipramine
Page last updated: 2024-10-29

imipramine and Koch's Disease

imipramine has been researched along with Koch's Disease in 3 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Research Excerpts

ExcerptRelevanceReference
"We describe inhibition of Mycobacterium tuberculosis topoisomerase I (MttopoI), an essential mycobacterial enzyme, by two related compounds, imipramine and norclomipramine, of which imipramine is clinically used as an antidepressant."3.81Targeting Mycobacterium tuberculosis topoisomerase I by small-molecule inhibitors. ( Ahmed, W; Bhat, RS; Bradley, EK; Ekins, S; Godbole, AA; Nagaraja, V, 2015)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Godbole, AA1
Ahmed, W1
Bhat, RS1
Bradley, EK1
Ekins, S1
Nagaraja, V1
LEVENDEL, L1
LAKATOS, M1
VARADY, T1
Piéron, R1
Marien, C1
Jagueux, M1

Other Studies

3 other studies available for imipramine and Koch's Disease

ArticleYear
Targeting Mycobacterium tuberculosis topoisomerase I by small-molecule inhibitors.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:3

    Topics: Amino Acid Motifs; Bacterial Proteins; Binding Sites; DNA; DNA Topoisomerases, Type I; DNA, Bacteria

2015
[The use of new tranquilizers (Frenolon, Melipramin, Hirepin) in the therapy of tuberculosis, with special reference to the alcoholic tuberculosis patients].
    Tuberkulozis, 1962, Volume: 15

    Topics: Chlorpropamide; Imipramine; Promethazine; Reserpine; Tranquilizing Agents; Tuberculosis; Tuberculosi

1962
[Jaundice and rifampicin].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1971, Apr-26, Volume: 47, Issue:20

    Topics: Aged; Chemical and Drug Induced Liver Injury; Female; Humans; Imipramine; Isoniazid; Jaundice; Liver

1971