imipramine has been researched along with Irritable Bowel Syndrome in 6 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Irritable Bowel Syndrome: A disorder with chronic or recurrent colonic symptoms without a clearcut etiology. This condition is characterized by chronic or recurrent ABDOMINAL PAIN, bloating, MUCUS in FECES, and an erratic disturbance of DEFECATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the efficacy of low-dose imipramine in relieving symptoms associated with the irritable bowel syndrome (IBS)." | 9.14 | A randomized controlled trial of imipramine in patients with irritable bowel syndrome. ( Abdul-Baki, H; Aoun, E; Azar, C; Chaar, H; El Hajj, II; Elzahabi, L; Sharara, AI; Skoury, A, 2009) |
| "Citalopram was not superior to placebo." | 6.73 | Antidepressant therapy (imipramine and citalopram) for irritable bowel syndrome: a double-blind, randomized, placebo-controlled trial. ( Boyce, P; Huskic, S; Jones, M; Kellow, JE; Talley, NJ; Tennant, C, 2008) |
| "Curcumin is a biologically active phytochemical presents in turmeric and has pharmacological actions that benefit patients with depression and anxiety." | 5.42 | The effect of curcumin on the brain-gut axis in rat model of irritable bowel syndrome: involvement of 5-HT-dependent signaling. ( Li, J; Pan, J; Wang, R; Wu, S; Xie, X; Xu, Y; Yu, X; Yu, Y; Zheng, L, 2015) |
| "To study the efficacy of low-dose imipramine in relieving symptoms associated with the irritable bowel syndrome (IBS)." | 5.14 | A randomized controlled trial of imipramine in patients with irritable bowel syndrome. ( Abdul-Baki, H; Aoun, E; Azar, C; Chaar, H; El Hajj, II; Elzahabi, L; Sharara, AI; Skoury, A, 2009) |
| "Citalopram was not superior to placebo." | 2.73 | Antidepressant therapy (imipramine and citalopram) for irritable bowel syndrome: a double-blind, randomized, placebo-controlled trial. ( Boyce, P; Huskic, S; Jones, M; Kellow, JE; Talley, NJ; Tennant, C, 2008) |
| "Curcumin is a biologically active phytochemical presents in turmeric and has pharmacological actions that benefit patients with depression and anxiety." | 1.42 | The effect of curcumin on the brain-gut axis in rat model of irritable bowel syndrome: involvement of 5-HT-dependent signaling. ( Li, J; Pan, J; Wang, R; Wu, S; Xie, X; Xu, Y; Yu, X; Yu, Y; Zheng, L, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Nozu, T | 1 |
| Miyagishi, S | 1 |
| Ishioh, M | 1 |
| Takakusaki, K | 1 |
| Okumura, T | 1 |
| Yu, Y | 1 |
| Wu, S | 1 |
| Li, J | 1 |
| Wang, R | 1 |
| Xie, X | 1 |
| Yu, X | 1 |
| Pan, J | 1 |
| Xu, Y | 1 |
| Zheng, L | 1 |
| Abdul-Baki, H | 1 |
| El Hajj, II | 1 |
| Elzahabi, L | 1 |
| Azar, C | 1 |
| Aoun, E | 1 |
| Skoury, A | 1 |
| Chaar, H | 1 |
| Sharara, AI | 1 |
| Teitelbaum, JE | 1 |
| Arora, R | 1 |
| Daling, AH | 1 |
| Holtman, GA | 1 |
| Laseur, MM | 1 |
| Weinans, MA | 1 |
| Lisman-van Leeuwen, Y | 1 |
| Talley, NJ | 1 |
| Kellow, JE | 1 |
| Boyce, P | 1 |
| Tennant, C | 1 |
| Huskic, S | 1 |
| Jones, M | 1 |
2 trials available for imipramine and Irritable Bowel Syndrome
| Article | Year |
|---|---|
A randomized controlled trial of imipramine in patients with irritable bowel syndrome.
Topics: Adult; Antidepressive Agents, Tricyclic; Double-Blind Method; Female; Humans; Imipramine; Irritable | 2009 |
Antidepressant therapy (imipramine and citalopram) for irritable bowel syndrome: a double-blind, randomized, placebo-controlled trial.
Topics: Adult; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Citalopram; Doubl | 2008 |
4 other studies available for imipramine and Irritable Bowel Syndrome
| Article | Year |
|---|---|
Imipramine improves visceral sensation and gut barrier in rat models of irritable bowel syndrome.
Topics: Abdominal Muscles; Animals; Antidepressive Agents, Tricyclic; Colon; Corticotropin-Releasing Hormone | 2020 |
The effect of curcumin on the brain-gut axis in rat model of irritable bowel syndrome: involvement of 5-HT-dependent signaling.
Topics: Animals; Anxiety; Brain-Derived Neurotrophic Factor; Colon; Curcumin; Cyclic AMP Response Element-Bi | 2015 |
Long-term efficacy of low-dose tricyclic antidepressants for children with functional gastrointestinal disorders.
Topics: Abdominal Pain; Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Child, Preschool | 2011 |
Observational research: the pitfall of drawing firm conclusions about efficacy.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Female; Humans; Imipramine; Irritable Bowel Syndrom | 2011 |