Page last updated: 2024-10-29

imipramine and Hypoxia

imipramine has been researched along with Hypoxia in 7 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.

Research Excerpts

ExcerptRelevanceReference
"This study tested if the antidepressant imipramine or the mood stabilizers lithium and sodium valproate regulated pathophysiological serine-dephosphorylation of GSK3 caused by hypoxia in mouse brain in vivo."7.73Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: protection by mood stabilizers and imipramine. ( De Sarno, P; Eom, TY; Jope, RS; Roh, MS; Roth, KA; Zmijewska, AA, 2005)
"This study tested if the antidepressant imipramine or the mood stabilizers lithium and sodium valproate regulated pathophysiological serine-dephosphorylation of GSK3 caused by hypoxia in mouse brain in vivo."3.73Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: protection by mood stabilizers and imipramine. ( De Sarno, P; Eom, TY; Jope, RS; Roh, MS; Roth, KA; Zmijewska, AA, 2005)
" The antidepressants pyrazidol, azaphen, imipramine and moclobemide as well as the nootropic drug piracetam prolonged the life of animals in conditions of hypoxic and hemic hypoxia and increased the survival rate of rats in circulatory hypoxia."3.68[Effects of antidepressive agents on tolerance of hypoxia and physical exercise]. ( Andreeva, NI; Golovina, SM; MashkovskiÄ­, MD; Parshin, VA, 1991)
"Cardiac ischemia and anoxia induce massive norepinephrine (NE) release, which is mediated by a reverse operation of uptake-1 and can be suppressed by uptake-1 inhibitors."1.30Protection of neuronal uptake-1 inhibitors in ischemic and anoxic hearts by norepinephrine-dependent and -independent mechanisms. ( Dart, AM; Du, XJ; Esler, MD; Little, PJ; Woodcock, EA, 1998)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roh, MS1
Eom, TY1
Zmijewska, AA1
De Sarno, P1
Roth, KA1
Jope, RS1
Fischbach, R1
Harrer, G1
Harrer, H1
Du, XJ1
Woodcock, EA1
Little, PJ1
Esler, MD1
Dart, AM1
Steinberg, H1
Bassett, DJ1
Fisher, AB1
Andreeva, NI1
Golovina, SM1
Parshin, VA1
MashkovskiÄ­, MD1
Lee, SL1
Dunn, J1
Yu, FS1
Fanburg, BL1
Kaeser, HE1

Other Studies

7 other studies available for imipramine and Hypoxia

ArticleYear
Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: protection by mood stabilizers and imipramine.
    Biological psychiatry, 2005, Feb-01, Volume: 57, Issue:3

    Topics: Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain; Carbon Dioxide; Dose-Response Rel

2005
[Changes in the oxygen deficiency tolerance in man induced by psychopharmaca].
    Arzneimittel-Forschung, 1966, Volume: 16, Issue:2

    Topics: Depression; Humans; Hypoxia; Imipramine

1966
Protection of neuronal uptake-1 inhibitors in ischemic and anoxic hearts by norepinephrine-dependent and -independent mechanisms.
    Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Animals; Cocaine; Desipramine; Dopamine Uptake Inhibitors; Drug Intera

1998
Depression of pulmonary 5-hydroxytryptamine uptake by metabolic inhibitors.
    The American journal of physiology, 1975, Volume: 228, Issue:5

    Topics: Animals; Biological Transport, Active; Carbon Radioisotopes; Chlorpromazine; Chromatography, Thin La

1975
[Effects of antidepressive agents on tolerance of hypoxia and physical exercise].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 112, Issue:8

    Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzamides; Carbazoles; Carbolines

1991
Serotonin uptake and configurational change of bovine pulmonary artery smooth muscle cells in culture.
    Journal of cellular physiology, 1989, Volume: 138, Issue:1

    Topics: Animals; Cattle; Cell Division; Cells, Cultured; Hypoxia; Imipramine; Microscopy, Phase-Contrast; Mu

1989
[Therapy of polyneuritides].
    Deutsche medizinische Wochenschrift (1946), 1971, Sep-03, Volume: 96, Issue:36

    Topics: Butyrophenones; Chlorpromazine; Glucocorticoids; Humans; Hypoxia; Imipramine; Methotrimeprazine; Nor

1971