imipramine has been researched along with Hypotension in 37 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reboxetine is as effective as imipramine in the treatment of depression in elderly patients but is at least as well tolerated with a lower risk of hypotension and related symptoms, fewer serious adverse events, adverse event-related withdrawals and treatment-related adverse events." | 9.09 | Reboxetine versus imipramine in the treatment of elderly patients with depressive disorders: a double-blind randomised trial. ( Bercoff, E; Chiu, E; Katona, C; Tack, P; Versiani, M; Woelk, H, 1999) |
| "Alpha 2-adrenergic receptor changes during antidepressant treatment were studied using 3H-yohimbine binding to human platelet membranes and clonidine-induced hypotension." | 9.06 | Alpha 2-adrenergic receptor sensitivity in depressed patients: relation between 3H-yohimbine binding to platelet membranes and clonidine-induced hypotension. ( Gelenberg, AJ; Lydiard, RB; Wolfe, N, 1989) |
| " The case of a 35-year-old man with an occult pheochromocytoma presenting with hypotension and cardiogenic shock shortly after beginning imipramine therapy is presented." | 8.79 | Imipramine-provoked paradoxical pheochromocytoma crisis: a case of cardiogenic shock. ( Ferguson, KL, 1994) |
| "Reboxetine is as effective as imipramine in the treatment of depression in elderly patients but is at least as well tolerated with a lower risk of hypotension and related symptoms, fewer serious adverse events, adverse event-related withdrawals and treatment-related adverse events." | 5.09 | Reboxetine versus imipramine in the treatment of elderly patients with depressive disorders: a double-blind randomised trial. ( Bercoff, E; Chiu, E; Katona, C; Tack, P; Versiani, M; Woelk, H, 1999) |
| "Alpha 2-adrenergic receptor changes during antidepressant treatment were studied using 3H-yohimbine binding to human platelet membranes and clonidine-induced hypotension." | 5.06 | Alpha 2-adrenergic receptor sensitivity in depressed patients: relation between 3H-yohimbine binding to platelet membranes and clonidine-induced hypotension. ( Gelenberg, AJ; Lydiard, RB; Wolfe, N, 1989) |
| " The case of a 35-year-old man with an occult pheochromocytoma presenting with hypotension and cardiogenic shock shortly after beginning imipramine therapy is presented." | 4.79 | Imipramine-provoked paradoxical pheochromocytoma crisis: a case of cardiogenic shock. ( Ferguson, KL, 1994) |
| "Enuresis is a common problem often treated effectively with imipramine hydrochloride." | 3.66 | Treatment of imipramine overdose in children. ( Cromie, WJ; Greene, AS, 1981) |
| "Nomifensine has demonstrated efficacy in several animal models that have been found to be predictive of clinical antidepressant activity, and has also been found to have a low potential for both cardiovascular and anticholinergic side effects." | 2.37 | Pharmacology of nomifensine: a review of animal studies. ( Fielding, S; Szewczak, MR, 1984) |
| "Imipramine was less arrhythmogenic and caused less fall in blood pressure for a given dose than amitriptyline or doxepin." | 1.26 | Comparison of the cardiovascular toxicity of three tricyclic antidepressant drugs: imipramine, amitriptyline, and doxepin. ( Brown, TC; Leversha, A, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (89.19) | 18.7374 |
| 1990's | 3 (8.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (2.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sert, A | 1 |
| Aypar, E | 1 |
| Odabas, D | 1 |
| Aygul, MU | 1 |
| DALMARK, MP | 1 |
| OLTMAN, JE | 1 |
| FRIEDMAN, S | 1 |
| LEBOURGES, J | 1 |
| SIMONSON, M | 1 |
| KINDMARK, CO | 1 |
| KJELLSTRAND, G | 1 |
| LINDHOLM, E | 1 |
| DELAY, J | 1 |
| DENIKER, P | 1 |
| BLACHLY, PH | 1 |
| SOULAYROL, R | 1 |
| LOB, H | 1 |
| POINSO, Y | 1 |
| KIND, H | 1 |
| ANGST, J | 1 |
| OSBORNE, MW | 1 |
| WINBURY, MM | 1 |
| Greene, AS | 1 |
| Cromie, WJ | 1 |
| Fielding, S | 1 |
| Szewczak, MR | 1 |
| Gold, MS | 1 |
| Pottash, AC | 1 |
| Marshall, JB | 1 |
| Forker, AD | 1 |
| Langou, RA | 1 |
| Van Dyke, C | 1 |
| Tahan, SR | 1 |
| Cohen, LS | 1 |
| Williams, JM | 1 |
| Hollingshed, MJ | 1 |
| Vasilakis, A | 1 |
| Morales, M | 1 |
| Prescott, JE | 1 |
| Graeber, GM | 1 |
| Ferguson, KL | 1 |
| Katona, C | 1 |
| Bercoff, E | 1 |
| Chiu, E | 1 |
| Tack, P | 1 |
| Versiani, M | 1 |
| Woelk, H | 1 |
| Brown, TC | 1 |
| Leversha, A | 1 |
| Wright, SP | 1 |
| Spiker, DG | 1 |
| Pugh, DD | 1 |
| Wolfe, N | 1 |
| Gelenberg, AJ | 1 |
| Lydiard, RB | 1 |
| Raskin, A | 2 |
| Schulterbrandt, JG | 1 |
| Reatig, N | 1 |
| Jaju, P | 1 |
| Sinha, JN | 1 |
| Srimal, RC | 1 |
| Ebert, MH | 1 |
| Shader, RI | 1 |
| Moccetti, T | 1 |
| Lichtlen, P | 1 |
| Casaccia, M | 1 |
| Halter, J | 1 |
| Mohr, P | 1 |
| Bauditz, W | 2 |
| Bartelheimer, HK | 2 |
| Lund-Larsen, G | 1 |
| Silvertssen, E | 1 |
| Lareng, L | 1 |
| Cathala, B | 1 |
| Viana, AP | 1 |
| Osswald, W | 1 |
| Slovis, TL | 1 |
| Ott, JE | 1 |
| Schuckit, M | 1 |
| Robins, E | 1 |
| Feighner, J | 1 |
| Kammerer, T | 1 |
| Tyano, S | 1 |
| Sacks, MH | 1 |
| Bonforte, RJ | 1 |
| Laser, RP | 1 |
| Dimich, I | 1 |
4 reviews available for imipramine and Hypotension
| Article | Year |
|---|---|
Pharmacology of nomifensine: a review of animal studies.
Topics: Acetylcholine; Adenylyl Cyclases; Aggression; Animals; Behavior, Animal; Brain Chemistry; Corpus Str | 1984 |
Cardiovascular effects of tricyclic antidepressant drugs: therapeutic usage, overdose, and management of complications.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular S | 1982 |
Imipramine-provoked paradoxical pheochromocytoma crisis: a case of cardiogenic shock.
Topics: Adrenal Gland Neoplasms; Adult; Cardiomyopathy, Dilated; Diagnosis, Differential; Emergency Service, | 1994 |
Cardiovascular effects of psychotropic drugs.
Topics: Antidepressive Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiovascular System; Humans; Hypotens | 1969 |
4 trials available for imipramine and Hypotension
| Article | Year |
|---|---|
Reboxetine versus imipramine in the treatment of elderly patients with depressive disorders: a double-blind randomised trial.
Topics: Aged; Aging; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depressive Disorder; Double-Bl | 1999 |
Alpha 2-adrenergic receptor sensitivity in depressed patients: relation between 3H-yohimbine binding to platelet membranes and clonidine-induced hypotension.
Topics: Adult; Blood Platelets; Blood Pressure; Cell Membrane; Clinical Trials as Topic; Clonidine; Depressi | 1989 |
A guide for drug use in depressive disorders.
Topics: Adolescent; Adult; Aged; Anxiety; Chlorpromazine; Clinical Trials as Topic; Depression; Diazepam; Dr | 1974 |
True and apparent side effects in a controlled trial of chlorpromazine and imipramine in depression.
Topics: Adult; Agranulocytosis; Chlorpromazine; Clinical Trials as Topic; Depression; Dermatitis; Edema; Eva | 1974 |
29 other studies available for imipramine and Hypotension
| Article | Year |
|---|---|
Temporary cardiac pacemaker in the treatment of junctional rhythm and hypotension due to imipramine intoxication.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Electrocardiography; Female; Fol | 2011 |
[Hypotension in a patient with heart disease treated with small doses of Tofranil].
Topics: Heart Diseases; Hypotension; Imipramine | 1962 |
PARGYLINE IN THE TREATMENT OF DEPRESSIVE ILLNESSES.
Topics: Antidepressive Agents; Antihypertensive Agents; Depression; Depressive Disorder; Hypotension; Imipra | 1963 |
[COMPLICATIONS OF ANTIDEPRESSIVE TREATMENTS].
Topics: Antidepressive Agents; Chlordiazepoxide; Diuretics; Hepatitis A; Hypotension; Hypotension, Orthostat | 1963 |
CONTROLLING MAO INHIBITOR HYPOTENSION.
Topics: Electroconvulsive Therapy; Fludrocortisone; Fluphenazine; Hypotension; Imipramine; Isocarboxazid; Mo | 1964 |
[SYMPTOMATOLOGY AND THERAPY OF TOFRANIL POISONING--A FEW REMARKS].
Topics: Adolescent; Anticonvulsants; Gastric Lavage; Hypotension; Imipramine; Myoclonus; Norepinephrine; Sui | 1964 |
[THE SECONDARY EFFECTS OF NEUROLEPTICS].
Topics: Antipsychotic Agents; Chlorpromazine; Fluphenazine; Humans; Hypotension; Imipramine; Methotrimeprazi | 1964 |
ON DEPRESSIVE REACTIONS.
Topics: Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Drug Therapy; Electroconvulsi | 1964 |
[INCIDENTS DUE TO DRUG INTERFERENCE WITH MONOAMINE OXIDASE INHIBITORS].
Topics: Amphetamine; Amphetamines; Coma; Hypotension; Imipramine; Meperidine; Monoamine Oxidase Inhibitors; | 1964 |
[ON AMBULATORY AND WARD MANAGEMENT OF DEPRESSIVE STATES WITH A DIBENZODIAZEPINE DERIVATIVE].
Topics: Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Drug Therapy; Hypotension; Hy | 1964 |
QUINDONIUM BROMIDE--SOME ASPECTS OF THE CARDIOVASCULAR PHARMACOLOGY.
Topics: Arrhythmias, Cardiac; Blood Pressure; Bromides; Cats; Dogs; Electrocardiography; Epinephrine; Guinea | 1965 |
Treatment of imipramine overdose in children.
Topics: Adult; Arrhythmias, Cardiac; Bicarbonates; Child; Child, Preschool; Coma; Diazepam; Drug Administrat | 1981 |
Depression: diagnosis and treatment with tricyclic antidepressants.
Topics: Age Factors; Antidepressive Agents, Tricyclic; Black People; Chromatography, High Pressure Liquid; D | 1981 |
Cardiovascular manifestations of tricyclic antidepressant overdose.
Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Blood Pressure; Cardiac Ou | 1980 |
Extracorporeal circulation in the management of severe tricyclic antidepressant overdose.
Topics: Adult; Drug Overdose; Extracorporeal Circulation; Fatal Outcome; Female; Hemodynamics; Humans; Hypot | 1994 |
Comparison of the cardiovascular toxicity of three tricyclic antidepressant drugs: imipramine, amitriptyline, and doxepin.
Topics: Amitriptyline; Animals; Arrhythmias, Cardiac; Cardiovascular System; Dogs; Doxepin; Hypotension; Imi | 1979 |
Usefulness of physostigmine in imipramine poisoning. A dramatic response in a child resistant to other therapy.
Topics: Arrhythmias, Cardiac; Child, Preschool; Coma; Epilepsy, Tonic-Clonic; Humans; Hypotension; Imipramin | 1976 |
Combining tricyclic and monoamine oxidase inhibitor antidepressants.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Drug Therapy, Combination; Humans; Hype | 1976 |
Inhibition of central vasomotor tone by imipramine.
Topics: Animals; Blood Pressure; Cats; Depression, Chemical; Electric Stimulation; Female; Hypotension; Imip | 1967 |
[Cardiac toxicity of tricyclic antidepressants].
Topics: Adult; Antidepressive Agents; Arrhythmias, Cardiac; Coronary Disease; Electrocardiography; Female; H | 1972 |
[Hemodialysis treatment of a 3 1-4-year-old child with imipramine poisoning].
Topics: Arrhythmias, Cardiac; Charcoal; Child, Preschool; Chloral Hydrate; Electrocardiography; Electroencep | 1970 |
[Imipramine cardiopathy].
Topics: Adult; Coma; Electric Stimulation Therapy; Electrocardiography; Female; Heart Ventricles; Humans; Hy | 1968 |
[Circulatory insufficiency in acute drug poisonings caused by central nervous system depressants].
Topics: Barbiturates; Humans; Hypnotics and Sedatives; Hypotension; Imipramine; Phenothiazines; Poisoning; R | 1969 |
Antiarrhythmic effects of proadifen hydrochloride (SKF 525-A).
Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Barb | 1970 |
[Treatment of imipramine poisoning at childhood].
Topics: Arrhythmias, Cardiac; Carbon; Child, Preschool; Chloral Hydrate; Coma; Gastric Lavage; Humans; Hypot | 1970 |
Postural hypotension from imipramine.
Topics: Antidotes; Child; Female; Humans; Hypotension; Imipramine; Physostigmine; Posture | 1971 |
Tricyclic antidepressants and monoamine oxidase inhibitors.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Animals; Depression; Desipramine; Drug | 1971 |
[Correction by dihydroergotamine of arterial pressure disorders induced by psychiatric chemotherapy].
Topics: Adolescent; Adult; Aged; Amitriptyline; Amobarbital; Antidepressive Agents; Barbiturates; Butyrophen | 1968 |
Cardiovascular complications of imipramine intoxication.
Topics: Accidents; Arrhythmias, Cardiac; Cardiac Output; Cardiovascular Diseases; Child, Preschool; Humans; | 1968 |