imipramine has been researched along with Hypotension, Orthostatic in 23 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Hypotension, Orthostatic: A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The physician must watch carefully for orthostatic hypotension when using imipramine in depressed patients with impaired LVP." | 5.27 | The use of imipramine in depressed patients with congestive heart failure. ( Bigger, JT; Cooper, TB; Giardina, EG; Glassman, AH; Johnson, LL; Roose, SP; Walsh, BT, 1983) |
| "The authors report on 12 men with ischemic heart disease who developed secondary depression following myocardial infarction or coronary artery bypass-graft surgery and were treated with imipramine hydrochloride for 4 weeks." | 3.66 | Cardiovascular and antidepressant effects of imipramine in the treatment of secondary depression in patients with ischemic heart disease. ( Barnes, R; Gumbrecht, G; Raskind, M; Veith, R, 1982) |
| "Olanzapine is an "atypical" antipsychotic agent with a high affinity for serotonin 5HT2A/C, 5HT3, 5HT6, and dopamine D1, D2, D3, D4 receptors." | 2.68 | Olanzapine: interaction study with imipramine. ( Callaghan, JT; Cerimele, BJ; Hoyes-Beehler, PJ; Kassahun, KJ; Kondraske, GV; Nyhart, EH, 1997) |
| "The increased orthostatic hypotension occurred early in treatment and at low doses of imipramine." | 2.66 | Orthostatic effect of imipramine and doxepin in depressed geriatric outpatients. ( Aldrich, J; Conolly, ME; Gerner, R; Hill, M; Jarvik, LF; Joseph, J; Linde, S; Mintz, J; Neshkes, RE; Rosen, R, 1985) |
| "The physician must watch carefully for orthostatic hypotension when using imipramine in depressed patients with impaired LVP." | 1.27 | The use of imipramine in depressed patients with congestive heart failure. ( Bigger, JT; Cooper, TB; Giardina, EG; Glassman, AH; Johnson, LL; Roose, SP; Walsh, BT, 1983) |
| "The incidence of orthostatic hypotension rose dramatically among those with severe heart disease." | 1.26 | Factors related to orthostatic hypotension associated with tricyclic antidepressants. ( Bigger, JT; Bruno, RL; Giardina, EG; Glassman, AH; Roose, SP; Rosenfeld, R; Walsh, BT, 1982) |
| "In our experience orthostatic hypotension is the commonest serious cardiovascular side-effect of imipramine." | 1.26 | Clinical characteristics of imipramine-induced orthostatic hypotension. ( Bigger, JT; Davies, M; Giardina, EV; Glassman, AH; Kantor, SJ; Perel, JM, 1979) |
| "They feel that the orthostatic hypotension seen in all seven patients represents a potentially serious problem with tricyclic antidepressants." | 1.26 | The cardiac effects of therapeutic plasma concentrations of imipramine. ( Bigger, JT; Giardina, EV; Glassman, AH; Kantor, SJ; Perel, JM, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (86.96) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| LEBOURGES, J | 1 |
| KIND, H | 1 |
| ANGST, J | 1 |
| Tulen, JH | 1 |
| Volkers, AC | 1 |
| van den Broek, WW | 1 |
| Bruijn, JA | 1 |
| Raskind, M | 1 |
| Veith, R | 1 |
| Barnes, R | 1 |
| Gumbrecht, G | 1 |
| Roose, SP | 5 |
| Glassman, AH | 7 |
| Siris, SG | 1 |
| Walsh, BT | 4 |
| Bruno, RL | 2 |
| Wright, LB | 1 |
| Jarvik, LF | 2 |
| Read, SL | 1 |
| Mintz, J | 2 |
| Neshkes, RE | 2 |
| Johnson, LL | 1 |
| Giardina, EG | 3 |
| Cooper, TB | 1 |
| Bigger, JT | 5 |
| Adler, L | 1 |
| Angrist, B | 1 |
| Lautin, A | 1 |
| Rotrosen, J | 1 |
| Rosenfeld, R | 1 |
| LaWall, JS | 1 |
| Laird, LK | 1 |
| Lydiard, RB | 1 |
| Morton, WA | 1 |
| Steele, TE | 1 |
| Kellner, C | 1 |
| Thompson, NM | 1 |
| Ballenger, JC | 1 |
| Callaghan, JT | 1 |
| Cerimele, BJ | 1 |
| Kassahun, KJ | 1 |
| Nyhart, EH | 1 |
| Hoyes-Beehler, PJ | 1 |
| Kondraske, GV | 1 |
| Giardina, EV | 2 |
| Kantor, SJ | 2 |
| Perel, JM | 2 |
| Davies, M | 1 |
| Tesar, GE | 1 |
| Rosenbaum, JF | 1 |
| Biederman, J | 1 |
| Weilburg, JB | 1 |
| Pollack, MH | 1 |
| Gross, CC | 1 |
| Falk, WE | 1 |
| Gastfriend, DR | 1 |
| Zusky, PM | 1 |
| Bouckoms, A | 1 |
| Woodring, S | 1 |
| Hyatt, M | 1 |
| Messer, M | 1 |
| Schneider, LS | 1 |
| Gerner, R | 1 |
| Joseph, J | 1 |
| Linde, S | 1 |
| Aldrich, J | 1 |
| Conolly, ME | 1 |
| Rosen, R | 1 |
| Hill, M | 1 |
| Collard, J | 1 |
| Dufrasne, M | 1 |
| Fraipont, J | 1 |
| Broor, SL | 1 |
| Wig, NN | 1 |
| Wahi, PL | 1 |
| Koehl, GW | 1 |
| Wenzel, JE | 1 |
1 review available for imipramine and Hypotension, Orthostatic
| Article | Year |
|---|---|
Tricyclic drugs in the treatment of depression.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Humans; Hypotension, Orthostatic | 1982 |
5 trials available for imipramine and Hypotension, Orthostatic
| Article | Year |
|---|---|
Sustained effects of phenelzine and tranylcypromine on orthostatic challenge in antidepressant-refractory depression.
Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; B | 2006 |
Pretreatment orthostatic hypotension in geriatric depression: predictor of response to imipramine and doxepin.
Topics: Aged; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans; H | 1983 |
Cardiovascular effects of imipramine, fluvoxamine, and placebo in depressed outpatients.
Topics: Adult; Aged; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Depressi | 1993 |
Olanzapine: interaction study with imipramine.
Topics: Adrenergic Uptake Inhibitors; Adult; Analysis of Variance; Antipsychotic Agents; Benzodiazepines; Cr | 1997 |
Orthostatic effect of imipramine and doxepin in depressed geriatric outpatients.
Topics: Age Factors; Aged; Depressive Disorder; Double-Blind Method; Doxepin; Female; Humans; Hypotension, O | 1985 |
17 other studies available for imipramine and Hypotension, Orthostatic
| Article | Year |
|---|---|
[COMPLICATIONS OF ANTIDEPRESSIVE TREATMENTS].
Topics: Antidepressive Agents; Chlordiazepoxide; Diuretics; Hepatitis A; Hypotension; Hypotension, Orthostat | 1963 |
[ON AMBULATORY AND WARD MANAGEMENT OF DEPRESSIVE STATES WITH A DIBENZODIAZEPINE DERIVATIVE].
Topics: Amitriptyline; Antidepressive Agents; Depression; Depressive Disorder; Drug Therapy; Hypotension; Hy | 1964 |
Cardiovascular and antidepressant effects of imipramine in the treatment of secondary depression in patients with ischemic heart disease.
Topics: Adult; Aged; Blood Pressure; Cardiac Complexes, Premature; Coronary Artery Bypass; Coronary Disease; | 1982 |
Comparison of imipramine- and nortriptyline-induced orthostatic hypotension: a meaningful difference.
Topics: Humans; Hypotension, Orthostatic; Imipramine; Middle Aged; Nortriptyline; Receptors, Adrenergic, alp | 1981 |
The use of imipramine in depressed patients with congestive heart failure.
Topics: Aged; Depressive Disorder; Electrocardiography; Female; Heart Failure; Heart Ventricles; Humans; Hyp | 1983 |
Differential effects of tricyclic antidepressants on mean arterial pressure in a hypertensive patient.
Topics: Blood Pressure; Depressive Disorder; Humans; Hypertension; Hypotension, Orthostatic; Imipramine; Mal | 1983 |
Factors related to orthostatic hypotension associated with tricyclic antidepressants.
Topics: Aged; Cardiac Output; Depressive Disorder; Female; Heart Diseases; Humans; Hypotension, Orthostatic; | 1982 |
Treatment of psychotropic-caused orthostatic hypotension.
Topics: Adult; Chlorpromazine; Female; Humans; Hypotension, Orthostatic; Imipramine; Middle Aged | 1980 |
Clinical characteristics of imipramine-induced orthostatic hypotension.
Topics: Adult; Aged; Blood Pressure; Depression; Female; Humans; Hypotension, Orthostatic; Imipramine; Male; | 1979 |
The cardiac effects of therapeutic plasma concentrations of imipramine.
Topics: Adult; Aged; Depression; Electrocardiography; Heart; Heart Conduction System; Humans; Hypotension, O | 1978 |
Orthostatic hypotension and antidepressant pharmacotherapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Blood Pressure; Female; Humans; H | 1987 |
Tricyclic antidepressants in depressed patients with cardiac conduction disease.
Topics: Antidepressive Agents, Tricyclic; Bundle-Branch Block; Depressive Disorder; Electrocardiography; Fem | 1987 |
Yohimbine and imipramine-induced orthostatia.
Topics: Depressive Disorder; Female; Humans; Hypotension, Orthostatic; Imipramine; Middle Aged; Yohimbine | 1986 |
PSOP for response to imipramine and doxepin.
Topics: Blood Pressure; Doxepin; Humans; Hypotension, Orthostatic; Imipramine | 1985 |
[Cardiovascular disorders caused by psychotropic drugs and their correction].
Topics: Cardiovascular Diseases; Central Nervous System Stimulants; Digitalis Glycosides; Electrocardiograph | 1969 |
A study of toxic effects of certain psychotropic drugs with special emphasis on their cardiotoxicity.
Topics: Adolescent; Adult; Cardiovascular Diseases; Chlorpromazine; Female; Humans; Hypotension, Orthostatic | 1973 |
Severe postural hypotension due to imipramine therapy.
Topics: Child; Enuresis; Female; Humans; Hypotension, Orthostatic; Imipramine | 1971 |