Page last updated: 2024-10-29

imipramine and Hyperpigmentation

imipramine has been researched along with Hyperpigmentation in 11 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Hyperpigmentation: Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance.

Research Excerpts

ExcerptRelevanceReference
"To inform clinicians of the potential for severe and persistent facial hyperpigmentation with the long-term use of imipramine."8.82Imipramine-associated hyperpigmentation. ( Dean, CE; Grund, FM, 2003)
"The purpose of this study is to describe the clinical and light microscopic findings in 4 patients with imipramine-induced hyperpigmentation and to better understand its origin."8.80Imipramine-induced hyperpigmentation: four cases and a review of the literature. ( Bhawan, J; Cohen, LM; McCalmont, TH; Ming, ME; Stefanato, CM, 1999)
"Blue or slate-gray hyperpigmentation is seen with a variety of medications, including imipramine."7.70Laser treatment of imipramine-induced hyperpigmentation. ( Atkin, DH; Fitzpatrick, RE, 2000)
"Imipramine is a tricyclic medication that has been used for the treatment of depression and other mood disorders."5.46Imipramine-induced hyperpigmentation. ( Bicknell, LM; Fernandez, M; McFaddin, CL; Parekh, P, 2017)
"We reported a case of photo-distributed hyperpigmentation due to imipramine and carried out a systematic search of the related articles using the search terms "tricyclic antidepressants" or "tricyclic antidepressive agents", and "hyperpigmentation" or "photosensitivity disorder"."5.22Tricyclic antidepressant-induced photosensitivity; A case report and systematic review. ( Boontaveeyuwat, E; Fityan, A; Mcfadden, JP; Rickaby, W; Sarkany, RPE; Steyn, M, 2022)
"To inform clinicians of the potential for severe and persistent facial hyperpigmentation with the long-term use of imipramine."4.82Imipramine-associated hyperpigmentation. ( Dean, CE; Grund, FM, 2003)
"The purpose of this study is to describe the clinical and light microscopic findings in 4 patients with imipramine-induced hyperpigmentation and to better understand its origin."4.80Imipramine-induced hyperpigmentation: four cases and a review of the literature. ( Bhawan, J; Cohen, LM; McCalmont, TH; Ming, ME; Stefanato, CM, 1999)
"We describe a patient with facial pigmentation of 26 years' duration that was associated with imipramine treatment for depression."3.73Imipramine-induced facial pigmentation: case report and literature review. ( Lin, AN; Metelitsa, AI; Nguyen, GK, 2005)
"Blue or slate-gray hyperpigmentation is seen with a variety of medications, including imipramine."3.70Laser treatment of imipramine-induced hyperpigmentation. ( Atkin, DH; Fitzpatrick, RE, 2000)
"Imipramine is a tricyclic medication that has been used for the treatment of depression and other mood disorders."1.46Imipramine-induced hyperpigmentation. ( Bicknell, LM; Fernandez, M; McFaddin, CL; Parekh, P, 2017)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's7 (63.64)29.6817
2010's1 (9.09)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Coffey, N1
Ali, Z1
Grau, J1
Boontaveeyuwat, E1
Steyn, M1
Rickaby, W1
Mcfadden, JP1
Sarkany, RPE1
Fityan, A1
Bicknell, LM1
McFaddin, CL1
Fernandez, M1
Parekh, P1
Izikson, L1
Anderson, RR1
Dean, CE1
Grund, FM1
Mendhekar, DN1
Metelitsa, AI1
Nguyen, GK1
Lin, AN1
Mehr, N1
Wu, JJ1
Dyson, SW1
Woseth, DM1
Ming, ME1
Bhawan, J1
Stefanato, CM1
McCalmont, TH1
Cohen, LM1
Atkin, DH1
Fitzpatrick, RE1
Angel, TA1
Stalkup, JR1
Hsu, S1

Reviews

4 reviews available for imipramine and Hyperpigmentation

ArticleYear
Imipramine-Induced Cutaneous and Iris Hyperpigmentation: A Case Report and Literature Review.
    The primary care companion for CNS disorders, 2022, Mar-29, Volume: 24, Issue:2

    Topics: Antidepressive Agents, Tricyclic; Humans; Hyperpigmentation; Imipramine; Iris; Skin

2022
Tricyclic antidepressant-induced photosensitivity; A case report and systematic review.
    Photodermatology, photoimmunology & photomedicine, 2022, Volume: 38, Issue:2

    Topics: Antidepressive Agents, Tricyclic; Female; Humans; Hyperpigmentation; Imipramine; Photosensitivity Di

2022
Imipramine-associated hyperpigmentation.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:6

    Topics: Aged; Humans; Hyperpigmentation; Imipramine; Male

2003
Imipramine-induced hyperpigmentation: four cases and a review of the literature.
    Journal of the American Academy of Dermatology, 1999, Volume: 40, Issue:2 Pt 1

    Topics: Aged; Antidepressive Agents, Tricyclic; Depression; Female; Humans; Hyperpigmentation; Imipramine; M

1999

Other Studies

7 other studies available for imipramine and Hyperpigmentation

ArticleYear
Imipramine-induced hyperpigmentation.
    Cutis, 2017, Volume: 100, Issue:3

    Topics: Antidepressive Agents, Tricyclic; Depressive Disorder; Diagnosis, Differential; Face; Female; Humans

2017
Delayed darkening of imipramine-induced hyperpigmentation after treatment with a Q-switched Nd:YAG laser followed by a Q-switched ruby laser.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2009, Volume: 35, Issue:3

    Topics: Aged; Antidepressive Agents, Tricyclic; Female; Hand; Humans; Hyperpigmentation; Imipramine; Lasers,

2009
Imipramine monotherapy-induced Hyperpigmentation in an adolescent girl.
    Indian journal of medical sciences, 2005, Volume: 59, Issue:9

    Topics: Adult; Antidepressive Agents, Tricyclic; Biopsy; Depressive Disorder, Major; Diagnosis, Differential

2005
Imipramine-induced facial pigmentation: case report and literature review.
    Journal of cutaneous medicine and surgery, 2005, Volume: 9, Issue:6

    Topics: Adrenergic Uptake Inhibitors; Adult; Aged; Antidepressive Agents, Tricyclic; Depression; Facial Derm

2005
Imipramine-induced hyperpigmentation of the skin.
    Dermatology online journal, 2007, Oct-13, Volume: 13, Issue:4

    Topics: Antidepressive Agents, Tricyclic; Face; Female; Humans; Hyperpigmentation; Imipramine; Middle Aged;

2007
Laser treatment of imipramine-induced hyperpigmentation.
    Journal of the American Academy of Dermatology, 2000, Volume: 43, Issue:1 Pt 1

    Topics: Aged; Antidepressive Agents, Tricyclic; Beryllium; Female; Humans; Hyperpigmentation; Imipramine; La

2000
Photodistributed blue-gray pigmentation of the skin associated with long-term imipramine use.
    International journal of dermatology, 2002, Volume: 41, Issue:6

    Topics: Aged; Antidepressive Agents, Tricyclic; Female; Humans; Hyperpigmentation; Imipramine; Photosensitiv

2002