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imipramine and Hyperactivity, Motor

imipramine has been researched along with Hyperactivity, Motor in 42 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Research Excerpts

ExcerptRelevanceReference
" Following repeated administration of the higher dose of IMI together with AMA, we observed an increase in clonidine-induced aggression in mice, and significant enhancement of D-amphetamine-induced locomotor hyperactivity, as well as phenylephrine-induced exploratory behavior, in rats."3.72The effect of combined treatment with imipramine and amantadine on the behavioral reactivity of central alpha1-adrenergic system in rats. ( Dziedzicka-Wasylewska, M; Faron-Górecka, A; Rogóz, Z; Solich, J, 2004)
"Although the FDA recommends imipramine hydrochloride (IMI) only for temporary relief of symptoms of enuresis nocturna (EN), the drug has been applied to a number of other pediatric situations, including the Hyperkinetic Syndrome (HS), childhood depression, somnambulism and pavor nocturnus, school phobia, petit mal epilepsy, allergies, autism, encorpresis and head-banging."3.65Imipramine and children: a review and some speculations about the mechanism of drug action. ( Gualtieri, CT, 1977)
"Methylphenidate-treated children showed significant weight loss but no significant changes in blood pressure or pulse."2.64Blood pressure and pulse changes in hyperactive children treated with imipramine and methylphenidate. ( Greenberg, LM; Yellin, AM, 1975)
" This temporary effect on growth is present during the first few years of treatment and seems related to drug dosage and to the presence or absence of drug holidays."1.26The effects of stimulant medication on the growth of hyperkinetic children. ( Hung, W; Lipman, RS; Overall, JE; Roche, AF, 1979)
" No correlations were found between dosage level and changes in weight and height percentiles."1.26Growth of hyperkinetic children taking methylphenidate, dextroamphetamine, or imipramine/desipramine. ( Gross, MD, 1976)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199037 (88.10)18.7374
1990's1 (2.38)18.2507
2000's4 (9.52)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Breuer, ME1
van Gaalen, MM1
Wernet, W1
Claessens, SE1
Oosting, RS1
Behl, B1
Korte, SM1
Schoemaker, H1
Gross, G1
Olivier, B1
Groenink, L1
WHITTIER, J1
HAYDU, G1
CRAWFORD, J1
Dziedzicka-Wasylewska, M1
Faron-Górecka, A1
Rogóz, Z1
Solich, J1
Dilsaver, SC1
Greden, JF1
Werry, JS1
Aman, MG1
Diamond, E1
Mills, IH1
Hill, P1
Taylor, E1
Araki, H1
Yamamoto, T1
Kobayashi, Y1
Futagami, K1
Kawasaki, H1
Gomita, Y1
Lambert, NM1
Windmiller, M1
Sandoval, J1
Moore, B1
Codd, JA1
Margolin, DI1
Gualtieri, CT2
Roche, AF1
Lipman, RS1
Overall, JE1
Hung, W1
Linnoila, M1
Jobson, K1
Staye, J1
Spring, C1
Yellin, AM2
Greenberg, L1
White, JH2
Gross, MD2
Greenberg, JS1
Quinn, PO4
Rapoport, JL4
Palmer, S1
Greenberg, LM1
Winsberg, BG3
Goldstein, S1
Yepes, LE1
Perel, JM1
Hayes, TA1
Panitch, ML1
Barker, E1
Sarma, PS1
Falk, MA1
Bialer, I3
Kupietz, S2
Tobias, J1
Waizer, J1
Hoffman, SP1
Polizos, P1
Engelhardt, DM1
Bradbard, G1
Riddle, KD1
Brooks, E1
Rapoport, J1
Quinn, P1
Scribanu, N1
Murphy, DL1
Omenn, GS1
Brown, D1
Press, M1
Ryback, WS1
Jorgensen, PA1
Jorgensen, SE1
Ullrich, JR1
Chinoy, MP1
Lamprecht, F1
Huessy, HR1
Peters, JE1
Randrup, A1
Munkvad, I1
Silver, LB1
Winsberg, HG1

Reviews

7 reviews available for imipramine and Hyperactivity, Motor

ArticleYear
Antidepressant withdrawal phenomena.
    Biological psychiatry, 1984, Volume: 19, Issue:2

    Topics: Adult; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac;

1984
An auditable protocol for treating attention deficit/hyperactivity disorder.
    Archives of disease in childhood, 2001, Volume: 84, Issue:5

    Topics: Algorithms; Attention Deficit Disorder with Hyperactivity; Child; Clinical Protocols; Clinical Trial

2001
Hyperactive children and the efficacy of psychoactive drugs as a treatment intervention.
    The American journal of orthopsychiatry, 1976, Volume: 46, Issue:2

    Topics: Amphetamines; Central Nervous System Stimulants; Child Behavior; Chlordiazepoxide; Chlorpromazine; C

1976
The hyperkinetic child syndrome and brain monoamines: pharmacology and therapeutic implications.
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:2

    Topics: Animals; Arousal; Attention; Brain; Child; Dextroamphetamine; Disease Models, Animal; Dopamine; Huma

1978
Genetic issues in the syndrome of minimal brain dysfunction.
    Seminars in psychiatry, 1973, Volume: 5, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Dextroamphetamine; Diseases in Twins; Female; Humans;

1973
Pharmacological studies on the brain mechanisms underlying two forms of behavioral excitation: stereotyped hyperactivity and "rage".
    Annals of the New York Academy of Sciences, 1969, Jul-30, Volume: 159, Issue:3

    Topics: Aggression; Amphetamine; Anger; Animals; Basal Ganglia; Behavior, Animal; Brain; Brain Chemistry; Di

1969
The neurologic learning disability syndrome.
    American family physician, 1971, Volume: 4, Issue:1

    Topics: Anorexia Nervosa; Anxiety; Attention; Attention Deficit Disorder with Hyperactivity; Brain Damage, C

1971

Trials

9 trials available for imipramine and Hyperactivity, Motor

ArticleYear
Effects of imipramine and methylphenidate on perceptual-motor performance of hyperactive children.
    Perceptual and motor skills, 1976, Volume: 42, Issue:43

    Topics: Adolescent; Child; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hyperkinesis; Imiprami

1976
One-year follow-up of hyperactive boys treated with imipramine or methylphenidate.
    The American journal of psychiatry, 1975, Volume: 132, Issue:3

    Topics: Administration, Oral; Body Weight; Child Behavior Disorders; Clinical Trials as Topic; Drug Evaluati

1975
Food additives and hyperactivity.
    Clinical pediatrics, 1975, Volume: 14, Issue:10

    Topics: Attention Deficit Disorder with Hyperactivity; Child; Clinical Trials as Topic; Feeding Behavior; Fo

1975
Caffeine in the treatment of children with minimal brain dysfunction or hyperkinetic syndrome.
    Psychosomatics, 1975, Volume: 16, Issue:1

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Caffeine; Child; Child, Preschool; Clinic

1975
Blood pressure and pulse changes in hyperactive children treated with imipramine and methylphenidate.
    The American journal of psychiatry, 1975, Volume: 132, Issue:12

    Topics: Adolescent; Blood Pressure; Body Weight; Child; Clinical Trials as Topic; Drug Evaluation; Female; H

1975
Effects of imipramine and dextroamphetamine on behavior of neuropsychiatrically impaired children.
    The American journal of psychiatry, 1972, Volume: 128, Issue:11

    Topics: Adolescent; Aggression; Anxiety; Brain Damage, Chronic; Child; Child Behavior Disorders; Clinical Tr

1972
Outpatient treatment of hyperactive school children with imipramine.
    The American journal of psychiatry, 1974, Volume: 131, Issue:5

    Topics: Ambulatory Care; Child; Child Behavior Disorders; Child Psychiatry; Clinical Trials as Topic; Drug E

1974
Imipramine and methylphenidate treatments of hyperactive boys. A double-blind comparison.
    Archives of general psychiatry, 1974, Volume: 30, Issue:6

    Topics: Attention; Child; Child Behavior Disorders; Child, Preschool; Clinical Trials as Topic; Cognition; D

1974
Platelet serotonin of hyperactive school age boys.
    The British journal of psychiatry : the journal of mental science, 1974, Volume: 125, Issue:0

    Topics: Blood Platelets; Child; Child Behavior Disorders; Clinical Trials as Topic; Humans; Hyperkinesis; Im

1974

Other Studies

26 other studies available for imipramine and Hyperactivity, Motor

ArticleYear
SSR149415, a non-peptide vasopressin V1b receptor antagonist, has long-lasting antidepressant effects in the olfactory bulbectomy-induced hyperactivity depression model.
    Naunyn-Schmiedeberg's archives of pharmacology, 2009, Volume: 379, Issue:1

    Topics: Animals; Antidepressive Agents; Antidiuretic Hormone Receptor Antagonists; Behavior, Animal; Depress

2009
Effect of imipramine (Tofranil) on depression and hyperkinesia in Huntington's disease.
    The American journal of psychiatry, 1961, Volume: 118

    Topics: Chorea; Depression; Depressive Disorder; Humans; Huntington Disease; Hyperkinesis; Imipramine; Movem

1961
The effect of combined treatment with imipramine and amantadine on the behavioral reactivity of central alpha1-adrenergic system in rats.
    Behavioural pharmacology, 2004, Volume: 15, Issue:2

    Topics: Administration, Oral; Adrenergic alpha-1 Receptor Agonists; Aggression; Amantadine; Amphetamine; Ani

2004
Imipramine and methylphenidate in hyperactive children.
    Journal of child psychology and psychiatry, and allied disciplines, 1980, Volume: 21, Issue:1

    Topics: Cardiovascular System; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind Metho

1980
Imipramine and amitriptyline in hyperactive children.
    QJM : monthly journal of the Association of Physicians, 1996, Volume: 89, Issue:4

    Topics: Amitriptyline; Child; Humans; Hyperkinesis; Imipramine; Methylphenidate

1996
Effect of methamphetamine and imipramine on cerebral ischemia-induced hyperactivity in Mongolian gerbils.
    Japanese journal of pharmacology, 2002, Volume: 88, Issue:3

    Topics: Animals; Antidepressive Agents, Tricyclic; Brain Ischemia; Carotid Artery, Common; Central Nervous S

2002
Hyperactive children: problems, issues and approaches.
    The New Zealand medical journal, 1978, Oct-25, Volume: 88, Issue:622

    Topics: Amphetamines; Behavior Therapy; Child; Child Behavior Disorders; Counseling; Dextroamphetamine; Fami

1978
Imipramine and children: a review and some speculations about the mechanism of drug action.
    Diseases of the nervous system, 1977, Volume: 38, Issue:5

    Topics: Adolescent; Age Factors; Child; Child, Preschool; Depression; Dopamine; Enuresis; Epilepsy, Absence;

1977
The effects of stimulant medication on the growth of hyperkinetic children.
    Pediatrics, 1979, Volume: 63, Issue:6

    Topics: Adolescent; Body Height; Body Weight; Child Behavior Disorders; Dextroamphetamine; Growth; Growth Di

1979
Characteristics of the therapeutic response to imipramine in hyperactive children.
    The American journal of psychiatry, 1979, Volume: 136, Issue:9

    Topics: Adolescent; Age Factors; Child; Child, Preschool; Desipramine; Drug Tolerance; Erythrocytes; Humans;

1979
The hyperactive child syndrome.
    American family physician, 1977, Volume: 15, Issue:4

    Topics: Child; Dextroamphetamine; Diphenhydramine; Humans; Hyperkinesis; Imipramine; Methylphenidate; Pemoli

1977
Methylphenidate (ritalin) and other drugs for treatment of hyperactive children.
    The Medical letter on drugs and therapeutics, 1977, Jul-01, Volume: 19, Issue:13

    Topics: Child; Deanol; Dextroamphetamine; Drug Interactions; Humans; Hyperkinesis; Imipramine; Methylphenida

1977
Growth of hyperkinetic children taking methylphenidate, dextroamphetamine, or imipramine/desipramine.
    Pediatrics, 1976, Volume: 58, Issue:3

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Dextroamphetamin

1976
Practical use of psychotropic drugs in children.
    Texas medicine, 1976, Volume: 72, Issue:9

    Topics: Adolescent; Child; Child Behavior Disorders; Enuresis; Humans; Hyperkinesis; Imipramine; Methylpheni

1976
Hyperkinesis and the schools.
    The Journal of school health, 1976, Volume: 46, Issue:2

    Topics: Amphetamines; Antidepressive Agents; Child; Humans; Hyperkinesis; Imipramine; Motor Activity; School

1976
Imipramine and electrocardiographic abnormalities in hyperactive children.
    The American journal of psychiatry, 1975, Volume: 132, Issue:5

    Topics: Atrioventricular Node; Child; Child Behavior Disorders; Drug Evaluation; Electrocardiography; Female

1975
Imipramine dosage in children: a comment on "imipramine and electrocardiographic abnormalities in hyperactive children".
    The American journal of psychiatry, 1975, Volume: 132, Issue:5

    Topics: Adult; Age Factors; Animals; Atrioventricular Node; Body Weight; Child; Child Behavior Disorders; Dr

1975
Drug treatment of hyperactivity in children.
    IMJ. Illinois medical journal, 1973, Volume: 144, Issue:2

    Topics: Age Factors; Child; Dextroamphetamine; Electroencephalography; Humans; Hyperkinesis; Imipramine; Met

1973
Imipramine therapy and seizures: three children treated for hyperactive behavior disorders.
    The American journal of psychiatry, 1973, Volume: 130, Issue:2

    Topics: Aggression; Brain Damage, Chronic; Child; Child Behavior Disorders; Child, Preschool; Dose-Response

1973
Sensitivity reaction to imipramine.
    The American journal of psychiatry, 1973, Volume: 130, Issue:8

    Topics: Affective Symptoms; Child; Child Behavior Disorders; Guilt; Humans; Hyperkinesis; Imipramine

1973
Side effects of methylphenidate.
    The American journal of psychiatry, 1973, Volume: 130, Issue:8

    Topics: Brain Damage, Chronic; Child; Child Behavior Disorders; Delusions; Dextroamphetamine; Evaluation Stu

1973
Letter: Biochemical aspects of sensitivity reactions.
    The American journal of psychiatry, 1973, Volume: 130, Issue:12

    Topics: Biogenic Amines; Brain; Child; Child, Preschool; Dextroamphetamine; Drug Hypersensitivity; Humans; H

1973
Minor physical anomalies and plasma dopamine-beta-hydroxylase activity in hyperactive boys.
    The American journal of psychiatry, 1974, Volume: 131, Issue:4

    Topics: Abnormalities, Multiple; Child; Dopamine beta-Hydroxylase; Female; Humans; Hyperkinesis; Imipramine;

1974
Letter: The adult hyperkinetic.
    The American journal of psychiatry, 1974, Volume: 131, Issue:6

    Topics: Adult; Behavior; Diagnosis, Differential; Humans; Hyperkinesis; Imipramine; Schizophrenia

1974
Minimal brain dysfunctions in children.
    American family physician, 1974, Volume: 10, Issue:1

    Topics: Amphetamine; Attention; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Comm

1974
A behavior rating scale for assessing improvement in behaviorally deviant children: a preliminary investigation.
    The American journal of psychiatry, 1972, Volume: 128, Issue:11

    Topics: Adolescent; Aggression; Anxiety; Attention; Child; Child Behavior Disorders; Dextroamphetamine; Diag

1972