imipramine has been researched along with Huntington Disease in 4 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| WHITTIER, J | 1 |
| HAYDU, G | 1 |
| CRAWFORD, J | 1 |
| Glaeser, BS | 1 |
| Vogel, WH | 1 |
| Oleweiler, DB | 1 |
| Hare, TA | 1 |
| Omenn, GS | 1 |
| Smith, L | 1 |
| Chase, TN | 1 |
1 review available for imipramine and Huntington Disease
| Article | Year |
|---|---|
Serotonergic mechanisms and extrapyramidal function in man.
Topics: 5-Hydroxytryptophan; Carbidopa; Cerebellar Diseases; Creutzfeldt-Jakob Syndrome; Down Syndrome; Extr | 1974 |
3 other studies available for imipramine and Huntington Disease
| Article | Year |
|---|---|
Effect of imipramine (Tofranil) on depression and hyperkinesia in Huntington's disease.
Topics: Chorea; Depression; Depressive Disorder; Humans; Huntington Disease; Hyperkinesis; Imipramine; Movem | 1961 |
GABA levels in cerebrospinal fluid of patients with Huntington's chorea: a preliminary report.
Topics: Adult; Aged; Aminobutyrates; Amitriptyline; Chlorpromazine; Diazepam; Female; gamma-Aminobutyric Aci | 1975 |
Platelet uptake of serotonin and dopamine in Huntington disease.
Topics: Adult; Blood Platelets; Dopamine; Female; Humans; Huntington Disease; Imipramine; Kinetics; Male; Mi | 1978 |