imipramine has been researched along with Heart Diseases in 27 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with imipramine and doxepin, but not placebo, was associated with significant improvement (P less than 0." | 2.65 | Cardiovascular effects of tricyclic antidepressants in depressed patients with chronic heart disease. ( Barnes, RF; Caldwell, JH; Gumbrecht, G; Raskind, MA; Ritchie, JL; Veith, RC, 1982) |
| "Imipramine treatment hit 13 disease clusters: tachycardia, palpitation, myocardial infarction, arrhythmias, heart block, precipitation of congestive heart failure; urinary retention, altered liver functions." | 1.38 | Prediction of adverse events by in vivo gene expression profiling exemplified for phytopharmaceuticals containing salicylates and the antidepressant imipramine. ( Freischmidt, A; Heilmann, J; Kelber, O; Koptina, A; Müller, J; Sadeghlar, F; Ulrich-Merzenich, G; Wagner, H; Zeitler, H, 2012) |
| "The hemodynamic, cardiographic, and initial pharmacokinetic characteristics of the de novo administration of the 2-hydroxymetabolite (2-OH-IMI) of imipramine (IMI), compared with its parent was studied in a swine preparation." | 1.28 | Imipramine and 2-hydroxyimipramine: comparative cardiotoxicity and pharmacokinetics in swine. ( Perel, JM; Pollock, BG, 1992) |
| "The incidence of orthostatic hypotension rose dramatically among those with severe heart disease." | 1.26 | Factors related to orthostatic hypotension associated with tricyclic antidepressants. ( Bigger, JT; Bruno, RL; Giardina, EG; Glassman, AH; Roose, SP; Rosenfeld, R; Walsh, BT, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (85.19) | 18.7374 |
| 1990's | 3 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ulrich-Merzenich, G | 1 |
| Koptina, A | 1 |
| Kelber, O | 1 |
| Freischmidt, A | 1 |
| Heilmann, J | 1 |
| Müller, J | 1 |
| Sadeghlar, F | 1 |
| Zeitler, H | 1 |
| Wagner, H | 1 |
| ATSMON, A | 1 |
| PINKHAS, J | 1 |
| Kristiansen, ES | 2 |
| LUNN, V | 1 |
| HAREL, A | 1 |
| WIJSENBEEK, H | 1 |
| GAULTIER, M | 1 |
| POTTER, M | 1 |
| JACOBSEN, P | 1 |
| DALMARK, MP | 1 |
| Gold, MS | 1 |
| Pottash, AC | 1 |
| Veith, RC | 1 |
| Raskind, MA | 1 |
| Caldwell, JH | 1 |
| Barnes, RF | 1 |
| Gumbrecht, G | 1 |
| Ritchie, JL | 1 |
| Glassman, AH | 1 |
| Walsh, BT | 1 |
| Roose, SP | 1 |
| Rosenfeld, R | 1 |
| Bruno, RL | 1 |
| Bigger, JT | 1 |
| Giardina, EG | 1 |
| Matsuda, M | 1 |
| Rushnak, MJ | 1 |
| McGovern, DP | 1 |
| Rotrekl, J | 1 |
| Náhunek, K | 1 |
| Homola, D | 1 |
| Svestka, J | 1 |
| Srnová, V | 1 |
| Rysánek, K | 1 |
| Pollock, BG | 1 |
| Perel, JM | 1 |
| Cohen, A | 1 |
| Weizman, A | 1 |
| Eldar, M | 1 |
| Rehavi, M | 1 |
| Gouret, CJ | 1 |
| Porsolt, R | 1 |
| Wettstein, JG | 1 |
| Puech, A | 1 |
| Soulard, C | 1 |
| Pascaud, X | 1 |
| Junien, JL | 1 |
| Hoehn-Saric, R | 1 |
| McLeod, DR | 1 |
| Zimmerli, WD | 1 |
| Moccetti, T | 2 |
| Boari, C | 1 |
| Raffi, GB | 1 |
| Orlando, E | 1 |
| Langslet, A | 1 |
| Postlethwaite, RJ | 1 |
| Price, DA | 1 |
| Adserballe, H | 1 |
| Crane, GE | 1 |
| Cunescu, V | 1 |
| Pârvu, V | 1 |
| Lichtlen, P | 1 |
| Sueblinvong, V | 1 |
| Wilson, JF | 1 |
3 reviews available for imipramine and Heart Diseases
| Article | Year |
|---|---|
[Acute poisoning with tricyclic antidepressive agents].
Topics: Antidepressive Agents; Brain Edema; Coma; Heart Diseases; Humans; Imipramine; Opipramol; Parasympath | 1969 |
Cardiac toxicity and psychotropic drugs.
Topics: Amitriptyline; Antidepressive Agents; Atrial Fibrillation; Death, Sudden; Electrocardiography; Heart | 1970 |
[Drug iatrogenesis in cardiology].
Topics: Antidepressive Agents; Antihypertensive Agents; Appetite Depressants; Blood Coagulation Disorders; C | 1971 |
2 trials available for imipramine and Heart Diseases
| Article | Year |
|---|---|
Cardiovascular effects of tricyclic antidepressants in depressed patients with chronic heart disease.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Blood Pressure; Chronic Disease | 1982 |
Proceedings: The comparison of the cardiotoxic effect of prothiaden, imipramine and amitriptyline.
Topics: Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Dibenzothiepins; Dothiepin; Heart Diseas | 1975 |
22 other studies available for imipramine and Heart Diseases
| Article | Year |
|---|---|
Prediction of adverse events by in vivo gene expression profiling exemplified for phytopharmaceuticals containing salicylates and the antidepressant imipramine.
Topics: Animals; Antidepressive Agents, Tricyclic; Benzyl Alcohols; Chemical and Drug Induced Liver Injury; | 2012 |
[Cardiovascular complications during treatment with Tofranil (imipramine)].
Topics: Cardiovascular Diseases; Cardiovascular System; Heart Diseases; Imipramine; Psychopharmacology | 1961 |
Cardiac complications during treatment with imipramin (Tofranil).
Topics: Depression; Depressive Disorder; Electrocardiography; Heart Diseases; Humans; Imipramine; Psychophar | 1961 |
[Cardiac complications in tofranil therapy].
Topics: Cardiovascular System; Heart Diseases; Imipramine; Psychopharmacology | 1960 |
[Cardiovascular complications during Tofranil treatment].
Topics: Cardiovascular Diseases; Cardiovascular System; Heart Diseases; Humans; Imipramine | 1962 |
[The heart and poisoning].
Topics: Antimalarials; Digitalis Glycosides; Heart; Heart Arrest; Heart Diseases; Humans; Imipramine | 1963 |
Cause of death in narcotic intoxication in recent years.
Topics: Cause of Death; Chlorprothixene; Heart Diseases; Humans; Imipramine; Kidney Diseases; Lung Diseases; | 1963 |
[Hypotension in a patient with heart disease treated with small doses of Tofranil].
Topics: Heart Diseases; Hypotension; Imipramine | 1962 |
Depression: diagnosis and treatment with tricyclic antidepressants.
Topics: Age Factors; Antidepressive Agents, Tricyclic; Black People; Chromatography, High Pressure Liquid; D | 1981 |
Factors related to orthostatic hypotension associated with tricyclic antidepressants.
Topics: Aged; Cardiac Output; Depressive Disorder; Female; Heart Diseases; Humans; Hypotension, Orthostatic; | 1982 |
[Cardiac disorders induced by antidepressant drugs (author's transl)].
Topics: Adult; Aged; Amitriptyline; Animals; Antidepressive Agents; Child; Dogs; Electrocardiography; Heart | 1980 |
Reversal of imipramine cardiotoxicity with physostigmine.
Topics: Adult; Female; Heart Diseases; Humans; Imipramine; Physostigmine | 1977 |
Imipramine and 2-hydroxyimipramine: comparative cardiotoxicity and pharmacokinetics in swine.
Topics: Animals; Arrhythmias, Cardiac; Blood Proteins; Cardiac Output; Electrocardiography; Half-Life; Heart | 1992 |
Long-term verapamil treatment increases [3H]imipramine binding in human platelets.
Topics: Blood Platelets; Carrier Proteins; Cell Membrane; Female; Heart Diseases; Humans; Imipramine; Male; | 1990 |
Biochemical and pharmacological evaluation of the novel antidepressant and serotonin uptake inhibitor 2-(3,4-Dichlorobenzyl)-2-dimethylamino-1-propanol hydrochloride.
Topics: Animals; Anticonvulsants; Antidepressive Agents; Behavior, Animal; Binding Sites; Brain Chemistry; C | 1990 |
Symptoms and treatment responses of generalized anxiety disorder patients with high versus low levels of cardiovascular complaints.
Topics: Adult; Alprazolam; Anxiety Disorders; Female; Heart Diseases; Heart Rate; Humans; Imipramine; Male; | 1989 |
[Cardiotoxic drugs].
Topics: Adult; Angina Pectoris; Anti-Bacterial Agents; Antipsychotic Agents; Chloroquine; Contraceptives, Or | 1973 |
[Abnormal electrocardiographic aspects during experimental acute imipramine poisoning].
Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Bundle-Branch Block; Electrocardiography; Heart; Heart | 1974 |
[Intoxications by tricyclic antidepressants in children].
Topics: Antidepressive Agents; Arrhythmias, Cardiac; Heart Diseases; Humans; Imipramine; Infant; Muscle Cram | 1974 |
Letter: Amitriptyline and imipramine poisoning in children.
Topics: Amitriptyline; Child; Enuresis; Heart Diseases; Humans; Imipramine; Phenytoin; Poisoning | 1974 |
[Changes in the heart due to phenothiazines and imipramine derivatives].
Topics: Aged; Anticonvulsants; Arrhythmias, Cardiac; Death, Sudden; Electrocardiography; Heart Diseases; Hea | 1971 |
Myocardial damage due to imipramine intoxication.
Topics: Aspartate Aminotransferases; Child, Preschool; Creatine Kinase; Electrocardiography; Electroencephal | 1969 |