imipramine has been researched along with Gastroesophageal Reflux in 6 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Gastroesophageal Reflux: Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We therefore assessed the benefit of imipramine in patients with esophageal hypersensitivity and functional heartburn." | 9.22 | Imipramine for Treatment of Esophageal Hypersensitivity and Functional Heartburn: A Randomized Placebo-Controlled Trial. ( Charatcharoenwitthaya, P; Leelakusolvong, S; Limsrivilai, J; Pausawasdi, N, 2016) |
| " We therefore assessed the benefit of imipramine in patients with esophageal hypersensitivity and functional heartburn." | 5.22 | Imipramine for Treatment of Esophageal Hypersensitivity and Functional Heartburn: A Randomized Placebo-Controlled Trial. ( Charatcharoenwitthaya, P; Leelakusolvong, S; Limsrivilai, J; Pausawasdi, N, 2016) |
| " report on a randomized control trial (RCT) testing the efficacy of imipramine for treating esophageal hypersensitivity and functional heartburn, the first RCT to test this therapy in this indication." | 3.83 | Low-Dose Tricyclics for Esophageal Hypersensitivity: Is it all Placebo Effect? ( Kahrilas, PJ; Keefer, L, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Limsrivilai, J | 1 |
| Charatcharoenwitthaya, P | 1 |
| Pausawasdi, N | 1 |
| Leelakusolvong, S | 1 |
| Keefer, L | 1 |
| Kahrilas, PJ | 1 |
| Marsden, SL | 1 |
| Ford, AC | 1 |
| Tyber, MA | 1 |
| Miller, ME | 1 |
| Perry, CJ | 1 |
| Siris, SG | 1 |
| Huguenard, P | 1 |
| Pinaudeau, Y | 1 |
| Roujas, F | 1 |
1 trial available for imipramine and Gastroesophageal Reflux
| Article | Year |
|---|---|
Imipramine for Treatment of Esophageal Hypersensitivity and Functional Heartburn: A Randomized Placebo-Controlled Trial.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Double-Blind Method; Esophageal pH Monitoring; Female | 2016 |
5 other studies available for imipramine and Gastroesophageal Reflux
| Article | Year |
|---|---|
Low-Dose Tricyclics for Esophageal Hypersensitivity: Is it all Placebo Effect?
Topics: Antidepressive Agents, Tricyclic; Female; Gastroesophageal Reflux; Heartburn; Humans; Hyperesthesia; | 2016 |
Imipramine for Treatment of Esophageal Hypersensitivity and Functional Heartburn.
Topics: Esophageal pH Monitoring; Esophagus; Gastroesophageal Reflux; Heartburn; Humans; Hypersensitivity; I | 2016 |
The relationship between hiatus hernia and tricyclic antidepressants: a report of five cases.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Esophagogastric Junction; Female; Gastroesop | 1975 |
Psychosis in association with combined cimetidine and imipramine treatment.
Topics: Adult; Cimetidine; Depressive Disorder; Drug Therapy, Combination; Female; Gastroesophageal Reflux; | 1987 |
[Toxic comas and generalized diffuse alveolitis].
Topics: Adult; Coma; Female; Fluphenazine; Gastroesophageal Reflux; Humans; Hyperbaric Oxygenation; Imiprami | 1970 |