Page last updated: 2024-10-29

imipramine and Fatigue

imipramine has been researched along with Fatigue in 12 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Fatigue: The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli.

Research Excerpts

ExcerptRelevanceReference
"Patients treated with imipramine plus CBT experienced less severe fatigue/weakness, dry mouth, and sweating and had a lower rate of dropout due to side effects compared with those treated with imipramine only."5.12A comparison of medication side effect reports by panic disorder patients with and without concomitant cognitive behavior therapy. ( Barlow, D; Goetz, R; Gorman, J; Gorman, L; Lewin, D; Marcus, SM; Martinez, J; Mosovich, S; Ray, S; Shear, MK; Woods, S, 2007)
" A metaregression did not reveal a statistically significant relation between the mean moclobemide dosage for each study and the risk ratio for response rates."2.43A metaanalysis of clinical trials comparing moclobemide with selective serotonin reuptake inhibitors for the treatment of major depressive disorder. ( Fava, M; Papakostas, GI, 2006)
"Significant withdrawal symptoms were found over seven symptom categories despite an average tapering period of 6."1.26Withdrawal symptoms after graduated cessation of imipramine in children. ( Kazdin, AE; Law, W; Petti, TA, 1981)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19909 (75.00)18.7374
1990's0 (0.00)18.2507
2000's3 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
NIESCHULZ, O1
BECK, D1
IDESTROEM, CM1
CADENIUS, B1
Papakostas, GI1
Fava, M1
Marcus, SM1
Gorman, J1
Shear, MK1
Lewin, D1
Martinez, J1
Ray, S1
Goetz, R1
Mosovich, S1
Gorman, L1
Barlow, D1
Woods, S1
Law, W1
Petti, TA1
Kazdin, AE1
Sovner, RD1
Tadano, T1
Nakagawasai, O1
Niijima, F1
Tan-No, K1
Kisara, K1
Pearlman, CA1
Greenberg, R1
Gall, H1
Kiplinger, GF1
Latz, A1
Kornetsky, C1
Bain, G1
Goldman, M1

Reviews

2 reviews available for imipramine and Fatigue

ArticleYear
A metaanalysis of clinical trials comparing moclobemide with selective serotonin reuptake inhibitors for the treatment of major depressive disorder.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2006, Volume: 51, Issue:12

    Topics: Depressive Disorder, Major; Disorders of Excessive Somnolence; Fatigue; Headache; Humans; Imipramine

2006
Medical-psychological implications of recent sleep research.
    Psychiatry in medicine, 1970, Volume: 1, Issue:4

    Topics: Adaptation, Psychological; Amphetamine; Barbiturates; Central Nervous System Stimulants; Chloral Hyd

1970

Trials

1 trial available for imipramine and Fatigue

ArticleYear
A comparison of medication side effect reports by panic disorder patients with and without concomitant cognitive behavior therapy.
    The American journal of psychiatry, 2007, Volume: 164, Issue:2

    Topics: Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy; Combined Modality Therapy; Fatigue;

2007

Other Studies

9 other studies available for imipramine and Fatigue

ArticleYear
[On swimming studies with mice].
    Medicina experimentalis : International journal of experimental medicine, 1963, Volume: 8

    Topics: Animals; Body Temperature; Fatigue; Imipramine; Mice; Swimming; Tranquilizing Agents

1963
[Autonomic research, therapy and prognosis of exhaustion depressions].
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1962, Volume: 90

    Topics: Autonomic Nervous System; Chlorprothixene; Depression; Depressive Disorder; Fatigue; Humans; Imipram

1962
IMIPRAMINE-DESMETHYLIMIPRAMINE. A PHARMACOLOGICAL STUDY ON HUMAN BEINGS.
    Psychopharmacologia, 1964, Jun-08, Volume: 5

    Topics: Blood Pressure; Blood Pressure Determination; Desipramine; Fatigue; Heart Rate; Humans; Imipramine;

1964
Withdrawal symptoms after graduated cessation of imipramine in children.
    The American journal of psychiatry, 1981, Volume: 138, Issue:5

    Topics: Anorexia; Child; Depressive Disorder; Fatigue; Female; Gastrointestinal Diseases; Headache; Humans;

1981
The clinical characteristics and treatment of atypical depression.
    The Journal of clinical psychiatry, 1981, Volume: 42, Issue:7

    Topics: Adult; Anxiety Disorders; Depressive Disorder; Desipramine; Fatigue; Female; Humans; Imipramine; Mal

1981
The effects of traditional tonics on fatigue in mice differ from those of the antidepressant imipramine: a pharmacological and behavioral study.
    The American journal of Chinese medicine, 2000, Volume: 28, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Drugs, Chinese Herbal; Fatigue; Imipram

2000
[Hidden depression--problem in internal medicine].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1970, Nov-01, Volume: 25, Issue:21

    Topics: Anxiety; Depression; Fatigue; Feeding and Eating Disorders; Humans; Imipramine; Psychophysiologic Di

1970
The effects of drugs on the rate of development of fatigue in mice.
    Texas reports on biology and medicine, 1967,Winter, Volume: 25, Issue:4

    Topics: Amphetamine; Animals; Dextroamphetamine; Fatigue; Imipramine; Male; Methods; Mice; Morphine; Pentoba

1967
Swimming performance of mice as affected by antidepressant drugs and baseline levels.
    Psychopharmacologia, 1966, Volume: 10, Issue:1

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Deanol; Desipramine; Dextroamphetamine; Fatigue; I

1966