Page last updated: 2024-10-29

imipramine and Epilepsy, Absence

imipramine has been researched along with Epilepsy, Absence in 7 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)

Research Excerpts

ExcerptRelevanceReference
"Although the FDA recommends imipramine hydrochloride (IMI) only for temporary relief of symptoms of enuresis nocturna (EN), the drug has been applied to a number of other pediatric situations, including the Hyperkinetic Syndrome (HS), childhood depression, somnambulism and pavor nocturnus, school phobia, petit mal epilepsy, allergies, autism, encorpresis and head-banging."3.65Imipramine and children: a review and some speculations about the mechanism of drug action. ( Gualtieri, CT, 1977)
" Chronic administration of the tricyclic antidepressant imipramine (15 mg/kg, i."1.35Dopamine-dependent nature of depression-like behavior in WAG/Rij rats with genetic absence epilepsy. ( Folomkina, AA; Kulikov, MA; Midzyanovskaya, IS; Sarkisova, KY, 2008)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sarkisova, KY2
Midzianovskaia, IS1
Kulikov, MA2
Midzyanovskaya, IS1
Folomkina, AA1
Fromm, GH3
Glass, JD2
Chattha, AS1
Martinez, AJ1
Silverman, M1
Wessel, HB1
Alvin, JD1
Van Horn, G1
Gualtieri, CT1
Petti, TA1
Campbell, M1
Amores, CY1
Thies, W1

Trials

1 trial available for imipramine and Epilepsy, Absence

ArticleYear
Imipramine in absence and myoclonic-astatic seizures.
    Neurology, 1978, Volume: 28, Issue:9 Pt 1

    Topics: Adolescent; Adult; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Epilepsies, Myocloni

1978

Other Studies

6 other studies available for imipramine and Epilepsy, Absence

ArticleYear
Depressive-like behavioral alterations and c-fos expression in the dopaminergic brain regions in WAG/Rij rats with genetic absence epilepsy.
    Behavioural brain research, 2003, Sep-15, Volume: 144, Issue:1-2

    Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain; Brain Chemistry; Choice Behavior

2003
Dopamine-dependent nature of depression-like behavior in WAG/Rij rats with genetic absence epilepsy.
    Neuroscience and behavioral physiology, 2008, Volume: 38, Issue:2

    Topics: Animals; Antidepressive Agents, Tricyclic; Bromocriptine; Depression; Dopamine; Dopamine Agonists; D

2008
Antiabsence drugs and inhibitory pathways.
    Neurology, 1980, Volume: 30, Issue:2

    Topics: Animals; Anticonvulsants; Cats; Cerebral Ventricles; Epilepsy, Absence; Ethosuximide; Imipramine; Ne

1980
Imipramine and children: a review and some speculations about the mechanism of drug action.
    Diseases of the nervous system, 1977, Volume: 38, Issue:5

    Topics: Adolescent; Age Factors; Child; Child, Preschool; Depression; Dopamine; Enuresis; Epilepsy, Absence;

1977
Imipramine and seizures.
    The American journal of psychiatry, 1975, Volume: 132, Issue:5

    Topics: Child, Preschool; Epilepsy; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Humans; Imipramine; Male; Mea

1975
Imipramine in epilepsy.
    Archives of neurology, 1972, Volume: 27, Issue:3

    Topics: Adolescent; Animals; Anticonvulsants; Cats; Child; Child, Preschool; Diazepam; Electroencephalograph

1972