imipramine has been researched along with Electrocardiogram QT Prolonged in 6 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Milnacipran is a specific serotonin and norepinephrine reuptake inhibitor, which has been widely used against major depressive episodes." | 1.36 | In vivo canine model comparison of cardiovascular effects of antidepressants milnacipran and imipramine. ( Adachi-Akahane, S; Hoshiai, K; Koizumi, S; Matsumoto, M; Mitsumori, Y; Nagayama, Y; Nakamura, Y; Sugiyama, A, 2010) |
| "Fluoxetine is a potent inhibitor of CYP2D6, and imipramine is metabolized by CYP2D6." | 1.33 | QTc prolongation associated with combination therapy of levofloxacin, imipramine, and fluoxetine. ( Blackmon, CL; Nykamp, DL; Roberson, AG; Schmidt, PE, 2005) |
| "No significant arrhythmias or tachycardias were observed." | 1.29 | ECG changes in pediatric patients on tricyclic antidepressants, desipramine, and imipramine. ( Giuffre, RM; Johnson, A; O'Malley, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavalli, A | 1 |
| Poluzzi, E | 1 |
| De Ponti, F | 1 |
| Recanatini, M | 1 |
| Mitsumori, Y | 1 |
| Nakamura, Y | 1 |
| Hoshiai, K | 1 |
| Nagayama, Y | 1 |
| Adachi-Akahane, S | 1 |
| Koizumi, S | 1 |
| Matsumoto, M | 1 |
| Sugiyama, A | 1 |
| Nykamp, DL | 1 |
| Blackmon, CL | 1 |
| Schmidt, PE | 1 |
| Roberson, AG | 1 |
| Roy, J | 1 |
| Vantol, B | 1 |
| Cowley, EA | 1 |
| Blay, J | 1 |
| Linsdell, P | 1 |
| Alderton, HR | 1 |
| Johnson, A | 1 |
| Giuffre, RM | 1 |
| O'Malley, K | 1 |
1 review available for imipramine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Tricyclic medication in children and the QT interval: case report and discussion.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Chil | 1995 |
5 other studies available for imipramine and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go- | 2002 |
In vivo canine model comparison of cardiovascular effects of antidepressants milnacipran and imipramine.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents, Tricyclic; Cyclopropanes; Dogs; Dose-R | 2010 |
QTc prolongation associated with combination therapy of levofloxacin, imipramine, and fluoxetine.
Topics: Anti-Infective Agents, Urinary; Antidepressive Agents; Cytochrome P-450 CYP2D6 Inhibitors; Drug Syne | 2005 |
Pharmacological separation of hEAG and hERG K+ channel function in the human mammary carcinoma cell line MCF-7.
Topics: Adenocarcinoma; Anti-Allergic Agents; Anti-Arrhythmia Agents; Astemizole; Breast Neoplasms; Cell Pro | 2008 |
ECG changes in pediatric patients on tricyclic antidepressants, desipramine, and imipramine.
Topics: Adolescent; Alberta; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Attention Deficit Disor | 1996 |