imipramine has been researched along with Disease Exacerbation in 2 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Subjects diagnosed with DSM-III-R chronic major depressive disorder or double depression (dysthymia with concurrent major depressive episode) were randomly assigned between February 1993 and December 1994 to 12 weeks of double-blind treatment with flexibly-dosed sertraline or imipramine, with crossover to the alternate drug in the absence of response." | 5.12 | Acute worsening of chronic depression during a double-blind, randomized clinical trial of antidepressant efficacy: differences by sex and menopausal status. ( Clary, CM; Harvey, AT; Kornstein, SG; Silkey, BS, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harvey, AT | 1 |
| Silkey, BS | 1 |
| Kornstein, SG | 1 |
| Clary, CM | 1 |
| Hayes, AM | 1 |
| Strauss, JL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Explicit and Implicit Change of Depression in Exposure-based Cognitive Therapy[NCT01012856] | Phase 2 | 142 participants (Anticipated) | Interventional | 2010-01-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for imipramine and Disease Exacerbation
| Article | Year |
|---|---|
Acute worsening of chronic depression during a double-blind, randomized clinical trial of antidepressant efficacy: differences by sex and menopausal status.
Topics: Adult; Cross-Over Studies; Depressive Disorder, Major; Disease Progression; Double-Blind Method; Dys | 2007 |
Dynamic systems theory as a paradigm for the study of change in psychotherapy: an application to cognitive therapy for depression.
Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy; Depressive Disord | 1998 |