imipramine has been researched along with Delayed Effects, Prenatal Exposure in 18 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A growing body of evidence has focused on the impact of mitochondrial disturbances in the development of depression, but little data exist regarding the effects of chronic administration of antidepressant drugs on the brain's mitochondrial protein profile." | 5.43 | The effect of chronic tianeptine administration on the brain mitochondria: direct links with an animal model of depression. ( Basta-Kaim, A; Budziszewska, B; Głombik, K; Kubera, M; Lasoń, W; Olszanecki, R; Ślusarczyk, J; Spedding, M; Stachowicz, A; Trojan, E, 2016) |
| "Our goal was to find out the impact of two antidepressant drugs with various mechanisms of action - imipramine and fluoxetine, on the frontal cortex mitochondria-enriched fraction in an animal model of depression based on the prenatal stress procedure." | 3.88 | Mitochondrial proteomics investigation of frontal cortex in an animal model of depression: Focus on chronic antidepressant drugs treatment. ( Basta-Kaim, A; Chamera, K; Głombik, K; Kotarska, K; Olszanecki, R; Ślusarczyk, J; Stachowicz, A; Suski, M; Trojan, E, 2018) |
| " Maternal exposure to imipramine in a dose equivalent to the therapeutic dose per unit body weight induced hyperthermic response to chlorpromazine in the male offspring, while normal control rats showed a marked hypothermia." | 3.69 | Transgenerational effects of maternal exposure to chemicals on the functional development of the brain in the offspring. ( Fujii, T, 1997) |
| " On the other hand, little is known about the impact of chronic administration of various antidepressant drugs on the brain mitochondria, as a target for the pharmacotherapy of depression." | 1.46 | Evaluation of the effectiveness of chronic antidepressant drug treatments in the hippocampal mitochondria - A proteomic study in an animal model of depression. ( Basta-Kaim, A; Budziszewska, B; Chamera, K; Głombik, K; Lasoń, W; Olszanecki, R; Ślusarczyk, J; Stachowicz, A; Suski, M; Trojan, E, 2017) |
| "A growing body of evidence has focused on the impact of mitochondrial disturbances in the development of depression, but little data exist regarding the effects of chronic administration of antidepressant drugs on the brain's mitochondrial protein profile." | 1.43 | The effect of chronic tianeptine administration on the brain mitochondria: direct links with an animal model of depression. ( Basta-Kaim, A; Budziszewska, B; Głombik, K; Kubera, M; Lasoń, W; Olszanecki, R; Ślusarczyk, J; Spedding, M; Stachowicz, A; Trojan, E, 2016) |
| " Maternal weight gained during the dosing period was decreased in a dose-related manner, but there were no dose-related differences in offspring body weights." | 1.27 | Early neurobehavioral and neurochemical alterations in rats prenatally exposed to imipramine. ( Ali, SF; Buelke-Sam, J; Newport, GD; Slikker, W, 1986) |
| "Doxepin was administered once daily during the first trimester (days 1-7), second trimester (days 8-14) or third trimester (days 15-21) of pregnancy, while imipramine was administered during the third trimester only." | 1.27 | Effects of prenatal exposure to tricyclic antidepressants on adrenergic responses in progeny. ( Field, FP; Simpkins, JW; Soltis, EE; Torosian, G, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (27.78) | 18.7374 |
| 1990's | 5 (27.78) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Głombik, K | 4 |
| Stachowicz, A | 3 |
| Trojan, E | 4 |
| Olszanecki, R | 3 |
| Ślusarczyk, J | 4 |
| Suski, M | 2 |
| Chamera, K | 3 |
| Budziszewska, B | 3 |
| Lasoń, W | 3 |
| Basta-Kaim, A | 4 |
| Kotarska, K | 1 |
| de la Garza, AL | 1 |
| Garza-Cuellar, MA | 1 |
| Silva-Hernandez, IA | 1 |
| Cardenas-Perez, RE | 1 |
| Reyes-Castro, LA | 1 |
| Zambrano, E | 1 |
| Gonzalez-Hernandez, B | 1 |
| Garza-Ocañas, L | 1 |
| Fuentes-Mera, L | 1 |
| Camacho, A | 1 |
| Kubera, M | 1 |
| Spedding, M | 1 |
| Yanpallewar, SU | 1 |
| Fernandes, K | 1 |
| Marathe, SV | 1 |
| Vadodaria, KC | 1 |
| Jhaveri, D | 1 |
| Rommelfanger, K | 1 |
| Ladiwala, U | 1 |
| Jha, S | 1 |
| Muthig, V | 1 |
| Hein, L | 1 |
| Bartlett, P | 1 |
| Weinshenker, D | 1 |
| Vaidya, VA | 1 |
| Morley-Fletcher, S | 1 |
| Darnaudéry, M | 1 |
| Mocaer, E | 1 |
| Froger, N | 1 |
| Lanfumey, L | 1 |
| Laviola, G | 1 |
| Casolini, P | 1 |
| Zuena, AR | 1 |
| Marzano, L | 1 |
| Hamon, M | 1 |
| Maccari, S | 1 |
| De Montis, GM | 1 |
| Devoto, P | 1 |
| Angioi, RM | 1 |
| Curreli, V | 1 |
| Tagliamonte, A | 1 |
| Fujii, T | 2 |
| Alonso, SJ | 1 |
| Castellano, MA | 1 |
| Quintero, M | 1 |
| Navarro, E | 1 |
| Zafar, H | 1 |
| Shelat, SG | 1 |
| Redei, E | 1 |
| Tejani-Butt, S | 1 |
| Romero, G | 1 |
| Toscano, E | 1 |
| Montero, D | 2 |
| De Felipe, MC | 1 |
| Del Rio, J | 2 |
| de Ceballos, ML | 1 |
| Abel, EL | 1 |
| Bilitzke, P | 1 |
| Ali, SF | 1 |
| Buelke-Sam, J | 1 |
| Newport, GD | 1 |
| Slikker, W | 1 |
| DeVane, CL | 1 |
| Simpkins, JW | 2 |
| Field, FP | 1 |
| Torosian, G | 1 |
| Soltis, EE | 1 |
| Ohtaki, Y | 1 |
18 other studies available for imipramine and Delayed Effects, Prenatal Exposure
| Article | Year |
|---|---|
Evaluation of the effectiveness of chronic antidepressant drug treatments in the hippocampal mitochondria - A proteomic study in an animal model of depression.
Topics: 14-3-3 Proteins; Animals; Antidepressive Agents; Cathepsin D; COP9 Signalosome Complex; Depression; | 2017 |
Mitochondrial proteomics investigation of frontal cortex in an animal model of depression: Focus on chronic antidepressant drugs treatment.
Topics: Animals; Antidepressive Agents; Depression; Depressive Disorder; Disease Models, Animal; Female; Flu | 2018 |
Maternal Flavonoids Intake Reverts Depression-Like Behaviour in Rat Female Offspring.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Diet; Disaccharides; Drug Interactions | 2019 |
The effect of chronic tianeptine administration on the brain mitochondria: direct links with an animal model of depression.
Topics: Animals; Anxiety; Behavior, Animal; Brain; Depression; Disease Models, Animal; Electrophoresis, Gel, | 2016 |
Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment.
Topics: Animals; Antidepressive Agents; Brain; Depressive Disorder; Female; Fluoxetine; Gene Expression; Imi | 2017 |
Alpha2-adrenoceptor blockade accelerates the neurogenic, neurotrophic, and behavioral effects of chronic antidepressant treatment.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Ad | 2010 |
Chronic treatment with imipramine reverses immobility behaviour, hippocampal corticosteroid receptors and cortical 5-HT(1A) receptor mRNA in prenatally stressed rats.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain Chemistry; Cerebral Cortex; Female; Hippocampus; Im | 2004 |
In utero exposure to methadone produces a stable decrease of the cortex 5-HT transport system in rats.
Topics: Animals; Biological Transport; Cerebral Cortex; Female; Imipramine; Methadone; Naloxone; Pregnancy; | 1983 |
Transgenerational effects of maternal exposure to chemicals on the functional development of the brain in the offspring.
Topics: Aggression; Aminobutyrates; Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Antineoplast | 1997 |
Action of antidepressant drugs on maternal stress-induced hypoactivity in female rats.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Dose-Response Relationsh | 1999 |
Fetal alcohol exposure alters serotonin transporter sites in rat brain.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Autoradiography; Brain; Carrier Proteins; Female; F | 2000 |
Effect of prenatal exposure to tianeptine on different neurotransmitter receptors and 5-HT-stimulated inositol phosphate formation in rat brain.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Clomipramine; Female; Imipramine; Inositol Phospha | 1992 |
Down-regulation of 3H-imipramine binding sites in rat cerebral cortex after prenatal exposure to antidepressants.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Binding Sites; Carrier Proteins; Cerebral Cort | 1990 |
Paternal alcohol exposure: paradoxical effect in mice and rats.
Topics: Animals; Behavior, Animal; Corticosterone; Ethanol; Female; Imipramine; Male; Metergoline; Mice; Pre | 1990 |
Early neurobehavioral and neurochemical alterations in rats prenatally exposed to imipramine.
Topics: Analysis of Variance; Animals; Brain; Dextroamphetamine; Dihydroalprenolol; Female; Imipramine; Male | 1986 |
Possible teratogenic effects of imipramine in the rat.
Topics: Animals; Dopamine; Estrus; Female; Hypothalamo-Hypophyseal System; Hypothalamus; Imipramine; Male; N | 1987 |
Effects of prenatal exposure to tricyclic antidepressants on adrenergic responses in progeny.
Topics: Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Doxepin; Female; Gestational Age; Heart R | 1985 |
Sex-related hyperthermic response to chlorpromazine in the offspring of rats treated with imipramine.
Topics: Animals; Body Temperature; Chlorpromazine; Female; Growth; Imipramine; Male; Pregnancy; Prenatal Exp | 1985 |