Page last updated: 2024-10-29

imipramine and Death, Sudden

imipramine has been researched along with Death, Sudden in 15 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.

Research Excerpts

ExcerptRelevanceReference
"This case study describes the sudden death of an additional child (8 years 9 months old, 29 kg in weight) treated with a tricyclic antidepressant, imipramine (100 mg orally, twice daily), and dextroamphetamine (10 mg orally every morning)."1.31Sudden death of a child treated with imipramine. Case study. ( Varley, CK, 2000)
"This case study describes the sudden deaths of two additional children treated with tricyclic antidepressants, one with desipramine, 3."1.30Case study: two additional sudden deaths with tricyclic antidepressants. ( McClellan, J; Varley, CK, 1997)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199011 (73.33)18.7374
1990's3 (20.00)18.2507
2000's1 (6.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
NOACK, CH1
Bigger, JT1
Weld, FM1
Antelman, SM1
Chiodo, LA1
Varley, CK2
McClellan, J1
Swanson, JR1
Jones, GR1
Krasselt, W1
Denmark, LN1
Ratti, F1
Tingelstad, JB1
Perz, D1
Moir, DC2
Cornwell, WB1
Dingwall-Fordyce, I1
Crooks, J1
O'Malley, K1
Turnbull, MJ1
Weir, RD1
Moccetti, T2
Saraf, KR1
Klein, DF1
Gittelman-Klein, R1
Groff, S1
Crane, GE1
Lichtlen, P1
Ziehank, E1

Reviews

3 reviews available for imipramine and Death, Sudden

ArticleYear
Drugs and sudden cardiac death.
    Annals of the New York Academy of Sciences, 1982, Volume: 382

    Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Coronary Disease; Death, Sudden; Diet Fads;

1982
Death of two subjects due to imipramine and desipramine metabolite accumulation during chronic therapy: a review of the literature and possible mechanisms.
    Journal of forensic sciences, 1997, Volume: 42, Issue:2

    Topics: Adult; Antidepressive Agents, Tricyclic; Child; Death, Sudden; Desipramine; Female; Humans; Imiprami

1997
Cardiac toxicity and psychotropic drugs.
    Diseases of the nervous system, 1970, Volume: 31, Issue:8

    Topics: Amitriptyline; Antidepressive Agents; Atrial Fibrillation; Death, Sudden; Electrocardiography; Heart

1970

Trials

2 trials available for imipramine and Death, Sudden

ArticleYear
Cardiotoxicity of amitriptyline.
    Lancet (London, England), 1972, Sep-16, Volume: 2, Issue:7777

    Topics: Acute Disease; Adult; Amitriptyline; Arrhythmias, Cardiac; Clinical Trials as Topic; Death, Sudden;

1972
Imipramine side effects in children.
    Psychopharmacologia, 1974, Jul-11, Volume: 37, Issue:3

    Topics: Adolescent; Anorexia Nervosa; Blood Pressure; Child; Constipation; Death, Sudden; Depression, Chemic

1974

Other Studies

10 other studies available for imipramine and Death, Sudden

ArticleYear
A death from overdosage of "tofranil".
    The Medical journal of Australia, 1960, Jul-30, Volume: 47(2)

    Topics: Death; Death, Sudden; Drug Overdose; Humans; Imipramine; Medical Records; Psychopharmacology

1960
Repeated antidepressant treatments induce a long-lasting dopamine autoreceptor subsensitivity: is daily treatment necessary for clinical efficacy? [proceedings].
    Psychopharmacology bulletin, 1981, Volume: 17, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Cocaine; Death, Sudden; Electrophysiology;

1981
Case study: two additional sudden deaths with tricyclic antidepressants.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1997, Volume: 36, Issue:3

    Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Child; Death, Sudden; Desipramine; Humans; I

1997
Sudden death of a child treated with imipramine. Case study.
    Journal of child and adolescent psychopharmacology, 2000,Winter, Volume: 10, Issue:4

    Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Central Nervous System Stimulants; Child; De

2000
The cardiotoxicity of the tricyclics.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1991, Volume: 30, Issue:5

    Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Attention Deficit Disorder with Hyperactivit

1991
[Sudden death of a child after tophranil poisoning].
    Pediatria polska, 1988, Volume: 63, Issue:4

    Topics: Accidents, Home; Child, Preschool; Death, Sudden; Female; Humans; Imipramine

1988
[Cardiotoxic drugs].
    Schweizerische medizinische Wochenschrift, 1973, Apr-28, Volume: 103, Issue:17

    Topics: Adult; Angina Pectoris; Anti-Bacterial Agents; Antipsychotic Agents; Chloroquine; Contraceptives, Or

1973
Tricyclic antidepressants and cardiac disease.
    American heart journal, 1973, Volume: 86, Issue:6

    Topics: Amitriptyline; Antidepressive Agents; Death, Sudden; Female; Heart; Heart Arrest; Humans; Imipramine

1973
[Changes in the heart due to phenothiazines and imipramine derivatives].
    Deutsche medizinische Wochenschrift (1946), 1971, Jun-18, Volume: 96, Issue:25

    Topics: Aged; Anticonvulsants; Arrhythmias, Cardiac; Death, Sudden; Electrocardiography; Heart Diseases; Hea

1971
[Sudden death of a debilitant child caused by an overdosage of imipramine].
    Das Deutsche Gesundheitswesen, 1968, Dec-12, Volume: 23, Issue:50

    Topics: Child; Death, Sudden; Humans; Imipramine; Intellectual Disability; Male

1968