imipramine has been researched along with Cognitive Decline in 3 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The role of the α2C-AR in modulating two key depression-related behaviours in the Flinders Sensitive Line (FSL) rat was studied using a dose-response analysis following subcutaneous administration with the selective α2C-AR antagonist ORM-10921 (0." | 1.46 | The α2C-adrenoceptor antagonist, ORM-10921, exerts antidepressant-like effects in the Flinders Sensitive Line rat. ( Harvey, BH; Sallinen, J; Shahid, M; Uys, MM, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Machado-Santos, AR | 1 |
| Loureiro-Campos, E | 1 |
| Patrício, P | 1 |
| Araújo, B | 1 |
| Alves, ND | 1 |
| Mateus-Pinheiro, A | 1 |
| Correia, JS | 1 |
| Morais, M | 1 |
| Bessa, JM | 1 |
| Sousa, N | 1 |
| Rodrigues, AJ | 1 |
| Oliveira, JF | 1 |
| Pinto, L | 1 |
| Riga, D | 1 |
| Kramvis, I | 1 |
| Koskinen, MK | 1 |
| van Bokhoven, P | 1 |
| van der Harst, JE | 1 |
| Heistek, TS | 1 |
| Jaap Timmerman, A | 1 |
| van Nierop, P | 1 |
| van der Schors, RC | 1 |
| Pieneman, AW | 1 |
| de Weger, A | 1 |
| van Mourik, Y | 1 |
| Schoffelmeer, ANM | 1 |
| Mansvelder, HD | 1 |
| Meredith, RM | 1 |
| Hoogendijk, WJG | 1 |
| Smit, AB | 1 |
| Spijker, S | 1 |
| Uys, MM | 1 |
| Shahid, M | 1 |
| Sallinen, J | 1 |
| Harvey, BH | 1 |
3 other studies available for imipramine and Cognitive Decline
| Article | Year |
|---|---|
Beyond New Neurons in the Adult Hippocampus: Imipramine Acts as a Pro-Astrogliogenic Factor and Rescues Cognitive Impairments Induced by Stress Exposure.
Topics: Animals; Antidepressive Agents; Cognitive Dysfunction; Disease Models, Animal; Hippocampus; Humans; | 2022 |
Hippocampal extracellular matrix alterations contribute to cognitive impairment associated with a chronic depressive-like state in rats.
Topics: Animals; CA1 Region, Hippocampal; Chondroitin ABC Lyase; Chondroitin Sulfate Proteoglycans; Chronic | 2017 |
The α2C-adrenoceptor antagonist, ORM-10921, exerts antidepressant-like effects in the Flinders Sensitive Line rat.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Antidepressive Agents; Behavior, Animal; Benzofura | 2017 |