imipramine has been researched along with Burkitt Lymphoma in 2 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Burkitt Lymphoma: A form of undifferentiated malignant LYMPHOMA usually found in central Africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of Burkitt lymphoma. The Epstein-Barr virus (HERPESVIRUS 4, HUMAN) has been isolated from Burkitt lymphoma cases in Africa and it is implicated as the causative agent in these cases; however, most non-African cases are EBV-negative.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Burkitt lymphoma is a rare malignancy arising from B cells." | 5.40 | The NADPH oxidase inhibitor imipramine-blue in the treatment of Burkitt lymphoma. ( Becker, J; Eberth, S; Klingenberg, M; Kube, D; Wilting, J, 2014) |
| "Burkitt lymphoma is a rare malignancy arising from B cells." | 1.40 | The NADPH oxidase inhibitor imipramine-blue in the treatment of Burkitt lymphoma. ( Becker, J; Eberth, S; Klingenberg, M; Kube, D; Wilting, J, 2014) |
| "Imipramine dimers were only found to be moderate inhibitors of the human serotonin transporter (hSERT) having IC(50) values in the micromolar region whilst the induction of cell death occurred independently of hSERT expression." | 1.39 | Basic N-interlinked imipramines show apoptotic activity against malignant cells including Burkitt's lymphoma. ( Bright, SA; Brinkø, A; Jensen, HH; Larsen, MT; Sinning, S; Williams, DC, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bright, SA | 1 |
| Brinkø, A | 1 |
| Larsen, MT | 1 |
| Sinning, S | 1 |
| Williams, DC | 1 |
| Jensen, HH | 1 |
| Klingenberg, M | 1 |
| Becker, J | 1 |
| Eberth, S | 1 |
| Kube, D | 1 |
| Wilting, J | 1 |
2 other studies available for imipramine and Burkitt Lymphoma
| Article | Year |
|---|---|
Basic N-interlinked imipramines show apoptotic activity against malignant cells including Burkitt's lymphoma.
Topics: Antineoplastic Agents; Apoptosis; Burkitt Lymphoma; Cell Death; Cell Line, Tumor; Cell Survival; Hum | 2013 |
The NADPH oxidase inhibitor imipramine-blue in the treatment of Burkitt lymphoma.
Topics: Animals; Antineoplastic Agents; Burkitt Lymphoma; Cell Line, Tumor; Cell Proliferation; Cell Surviva | 2014 |