imipramine has been researched along with Brain Ischemia in 10 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was aimed to determine whether imipramine chronic treatment promotes neurogenesis in the dentate gyrus (DG) and interferes with neuronal death in the CA1 subfield of the hippocampus after transient global cerebral ischemia (TGCI) in rats." | 7.76 | Imipramine enhances cell proliferation and decreases neurodegeneration in the hippocampus after transient global cerebral ischemia in rats. ( Castro, OW; de Oliveira, RM; Foresti, ML; Garcia-Cairasco, N; Milani, H; Romanini, CV; Schiavon, AP, 2010) |
| " Using the transient right middle cerebral artery occlusion- (MCAO-, 90 min) operated rats as an ischemia model in this study, we first observed that aggravation of anhedonia spontaneously occurred especially after 20 weeks of MCAO, and it was prevented by chronic antidepressants treatment (imipramine or fluvoxamine)." | 3.83 | Postischemic Anhedonia Associated with Neurodegenerative Changes in the Hippocampal Dentate Gyrus of Rats. ( Kasahara, J; Oka, N; Tezuka, K; Uchida, H, 2016) |
| "This study was aimed to determine whether imipramine chronic treatment promotes neurogenesis in the dentate gyrus (DG) and interferes with neuronal death in the CA1 subfield of the hippocampus after transient global cerebral ischemia (TGCI) in rats." | 3.76 | Imipramine enhances cell proliferation and decreases neurodegeneration in the hippocampus after transient global cerebral ischemia in rats. ( Castro, OW; de Oliveira, RM; Foresti, ML; Garcia-Cairasco, N; Milani, H; Romanini, CV; Schiavon, AP, 2010) |
| "The development of hind paw mechanical allodynia was measured after BCAO using the von Frey test." | 1.43 | Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia. ( Harada, S; Matsuura, W; Tokuyama, S, 2016) |
| "Global transient cerebral ischemia was performing with the four-vessels occlusion method." | 1.35 | Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances. ( Bantsiele, GB; Bentué-Ferrer, D; Bourin, M; Laviolle, B; Reymann, JM; Saïkali, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Monjas, L | 1 |
| Arce, MP | 1 |
| León, R | 1 |
| Egea, J | 1 |
| Pérez, C | 1 |
| Villarroya, M | 1 |
| López, MG | 1 |
| Gil, C | 1 |
| Conde, S | 1 |
| Rodríguez-Franco, MI | 1 |
| Pang, C | 1 |
| Cao, L | 1 |
| Wu, F | 1 |
| Wang, L | 1 |
| Wang, G | 1 |
| Yu, Y | 1 |
| Zhang, M | 1 |
| Chen, L | 2 |
| Wang, W | 1 |
| Lv, W | 1 |
| Zhu, J | 1 |
| Pan, J | 1 |
| Zhang, H | 1 |
| Xu, Y | 1 |
| Ding, L | 1 |
| Kasahara, J | 1 |
| Uchida, H | 1 |
| Tezuka, K | 1 |
| Oka, N | 1 |
| Matsuura, W | 1 |
| Harada, S | 1 |
| Tokuyama, S | 1 |
| Bantsiele, GB | 1 |
| Bentué-Ferrer, D | 1 |
| Saïkali, S | 1 |
| Laviolle, B | 1 |
| Bourin, M | 1 |
| Reymann, JM | 1 |
| Schiavon, AP | 1 |
| Milani, H | 1 |
| Romanini, CV | 1 |
| Foresti, ML | 1 |
| Castro, OW | 1 |
| Garcia-Cairasco, N | 1 |
| de Oliveira, RM | 1 |
| Kim, DW | 1 |
| Kim, DS | 1 |
| Kim, MJ | 1 |
| Kwon, SW | 1 |
| Ahn, EH | 1 |
| Jeong, HJ | 1 |
| Sohn, EJ | 1 |
| Dutta, S | 1 |
| Lim, SS | 1 |
| Cho, SW | 1 |
| Lee, KS | 1 |
| Park, J | 1 |
| Eum, WS | 1 |
| Hwang, HS | 1 |
| Choi, SY | 1 |
| Busch, KT | 1 |
| Schulz, H | 1 |
| Araki, H | 1 |
| Yamamoto, T | 1 |
| Kobayashi, Y | 1 |
| Futagami, K | 1 |
| Kawasaki, H | 1 |
| Gomita, Y | 1 |
| Ahlemeyer, B | 1 |
| Krieglstein, J | 1 |
10 other studies available for imipramine and Brain Ischemia
| Article | Year |
|---|---|
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Don | 2017 |
The effect of trans-resveratrol on post-stroke depression via regulation of hypothalamus-pituitary-adrenal axis.
Topics: Animals; Antidepressive Agents; Brain Ischemia; Depressive Disorder; Disease Models, Animal; Dose-Re | 2015 |
Postischemic Anhedonia Associated with Neurodegenerative Changes in the Hippocampal Dentate Gyrus of Rats.
Topics: Anhedonia; Animals; Antidepressive Agents; Brain Ischemia; Cell Proliferation; Dentate Gyrus; Diseas | 2016 |
Effects of Adjuvant Analgesics on Cerebral Ischemia-Induced Mechanical Allodynia.
Topics: Amines; Analgesics; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antico | 2016 |
Behavioral effects of four antidepressants on an ischemic rat model of emotional disturbances.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety Disorders; Behavior, Animal; Brain Isc | 2009 |
Imipramine enhances cell proliferation and decreases neurodegeneration in the hippocampus after transient global cerebral ischemia in rats.
Topics: Animals; Brain Ischemia; CA1 Region, Hippocampal; Cell Death; Cell Proliferation; Dentate Gyrus; Dou | 2010 |
Imipramine enhances neuroprotective effect of PEP-1-Catalase against ischemic neuronal damage.
Topics: Animals; Antidepressive Agents, Tricyclic; Astrocytes; Brain Ischemia; Catalase; Cell Survival; Cyst | 2011 |
[The acute psychiatric emergency].
Topics: Acute Disease; Aged; Alcoholism; Amitriptyline; Brain Ischemia; Cognition Disorders; Consciousness D | 1981 |
Effect of methamphetamine and imipramine on cerebral ischemia-induced hyperactivity in Mongolian gerbils.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain Ischemia; Carotid Artery, Common; Central Nervous S | 2002 |
Testing drug effects against hypoxic damage of cultured neurons during long-term recovery.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Brain Ischemia; Cell Count; Cell Survival; Cells, | 1989 |