Compounds > imipramine
Page last updated: 2024-10-29

imipramine and Asystole

imipramine has been researched along with Asystole in 21 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Research Excerpts

ExcerptRelevanceReference
" We present a case of massive imipramine overdose complicated by ventricular fibrillation and a prolonged period of cardiovascular collapse."7.69Tricyclic poisoning--successful management of ventricular fibrillation following massive overdose of imipramine. ( Alahakoon, TI; Bentley, SC; Sandeman, DJ, 1997)
"Physostigmine is a commonly used therapy for the anticholinergic manifestations of tricyclic antidepressant (TCA) overdose."5.26Asystole complicating physostigmine treatment of tricyclic antidepressant overdose. ( Pentel, P; Peterson, CD, 1980)
" We present a case of massive imipramine overdose complicated by ventricular fibrillation and a prolonged period of cardiovascular collapse."3.69Tricyclic poisoning--successful management of ventricular fibrillation following massive overdose of imipramine. ( Alahakoon, TI; Bentley, SC; Sandeman, DJ, 1997)
"This case study describes the sudden death of an additional child (8 years 9 months old, 29 kg in weight) treated with a tricyclic antidepressant, imipramine (100 mg orally, twice daily), and dextroamphetamine (10 mg orally every morning)."1.31Sudden death of a child treated with imipramine. Case study. ( Varley, CK, 2000)
"Physostigmine is a commonly used therapy for the anticholinergic manifestations of tricyclic antidepressant (TCA) overdose."1.26Asystole complicating physostigmine treatment of tricyclic antidepressant overdose. ( Pentel, P; Peterson, CD, 1980)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199019 (90.48)18.7374
1990's1 (4.76)18.2507
2000's1 (4.76)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GAULTIER, M2
POTTER, M2
PROUT, BJ1
YOUNG, J1
GODDARD, P1
Masters, AB1
Orr, DA1
Bramble, MG1
Pentel, P1
Peterson, CD1
Benesová, O2
Sandeman, DJ1
Alahakoon, TI1
Bentley, SC1
Varley, CK1
Jelínek, R1
Horák, J1
Soucek, K1
Reed, K1
McKim, HR1
Brown, KG1
McMichen, HU1
Briggs, DS1
Boari, C1
Raffi, GB1
Orlando, E1
Kanarek, KS1
Thomson, PD1
Levin, SE1
Moir, DC1
Crane, GE1
Attree, T1
Sawyer, P1
Turnbull, MJ1
Williams, RB1
Sherter, C1
Sidiropoulos, D1
Bickel, MH1
Pearson, JD1
Jones, ES1
Gabbe, DM1
Edwards, J1

Reviews

1 review available for imipramine and Asystole

ArticleYear
Cardiac toxicity and psychotropic drugs.
    Diseases of the nervous system, 1970, Volume: 31, Issue:8

    Topics: Amitriptyline; Antidepressive Agents; Atrial Fibrillation; Death, Sudden; Electrocardiography; Heart

1970

Other Studies

20 other studies available for imipramine and Asystole

ArticleYear
[The heart and poisoning].
    Coeur et medecine interne, 1963, Volume: 2

    Topics: Antimalarials; Digitalis Glycosides; Heart; Heart Arrest; Heart Diseases; Humans; Imipramine

1963
IMIPRAMINE POISONING IN CHILDHOOD AND SUGGESTED TREATMENT.
    British medical journal, 1965, Apr-10, Volume: 1, Issue:5440

    Topics: Antidepressive Agents; Coma; Diuresis; Electrocardiography; Gastric Lavage; Glucose; Heart Arrest; H

1965
Delayed death in imipramine poisoning.
    British medical journal, 1967, Sep-30, Volume: 3, Issue:5569

    Topics: Chlorpromazine; Female; Furosemide; Gastric Lavage; Heart Arrest; Humans; Imipramine; Infusions, Par

1967
Tricyclic antidepressant poisoning and prolonged external cardiac massage during asystole.
    British medical journal (Clinical research ed.), 1981, Oct-24, Volume: 283, Issue:6299

    Topics: Adult; Arrhythmias, Cardiac; Female; Heart Arrest; Heart Massage; Humans; Imipramine; Male; Prognosi

1981
Asystole complicating physostigmine treatment of tricyclic antidepressant overdose.
    Annals of emergency medicine, 1980, Volume: 9, Issue:11

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Bradycardia; Electroca

1980
To the pharmacological profile of maprotiline.
    Activitas nervosa superior, 1982, Volume: 24, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Animals; Anthracenes; Arousal; Chick Embryo; Depressive Disorder

1982
Tricyclic poisoning--successful management of ventricular fibrillation following massive overdose of imipramine.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:5

    Topics: Adrenergic Agonists; Adult; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Critical Care;

1997
Sudden death of a child treated with imipramine. Case study.
    Journal of child and adolescent psychopharmacology, 2000,Winter, Volume: 10, Issue:4

    Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Central Nervous System Stimulants; Child; De

2000
Cardiotoxicity of tricyclic antidepressants and maprotiline in the chick embryo. A comparative study.
    Activitas nervosa superior, 1978, Volume: 20, Issue:1

    Topics: Amitriptyline; Animals; Anthracenes; Antidepressive Agents, Tricyclic; Chick Embryo; Dothiepin; Hear

1978
ECG changes in pure impramine overdose as function of plasma level.
    Canadian Psychiatric Association journal, 1978, Volume: 23, Issue:8

    Topics: Adult; Desipramine; Electrocardiography; Female; Heart; Heart Arrest; Heart Conduction System; Human

1978
Tachyarrhythmia in severe imipramine overdose controlled by practolol.
    Archives of disease in childhood, 1972, Volume: 47, Issue:251

    Topics: Adrenergic beta-Antagonists; Child, Preschool; Coma; Electrocardiography; Heart Arrest; Humans; Imip

1972
[Abnormal electrocardiographic aspects during experimental acute imipramine poisoning].
    Minerva medica, 1974, Sep-19, Volume: 65, Issue:65

    Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Bundle-Branch Block; Electrocardiography; Heart; Heart

1974
The management of imipramine (Tofranil) intoxication in children.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, May-19, Volume: 47, Issue:19

    Topics: Adult; Anticonvulsants; Arrhythmias, Cardiac; Electrocardiography; Emergencies; Female; Gastric Lava

1973
Tricyclic antidepressants and cardiac disease.
    American heart journal, 1973, Volume: 86, Issue:6

    Topics: Amitriptyline; Antidepressive Agents; Death, Sudden; Female; Heart; Heart Arrest; Humans; Imipramine

1973
Interaction between digoxin and tricyclic antidepressants in the rat.
    European journal of pharmacology, 1972, Volume: 19, Issue:2

    Topics: Amitriptyline; Animals; Antidepressive Agents; Desipramine; Digoxin; Dose-Response Relationship, Dru

1972
Cardiac complications of tricyclic antidepressant therapy.
    Annals of internal medicine, 1971, Volume: 74, Issue:3

    Topics: Adult; Amitriptyline; Antidepressive Agents; Autopsy; Catecholamines; Drug Synergism; Electrocardiog

1971
[Fatal poisoning with a small dose of Imipramine in an infant].
    Schweizerische medizinische Wochenschrift, 1971, Jun-12, Volume: 101, Issue:23

    Topics: Brain Chemistry; Brain Death; Decerebrate State; Exchange Transfusion, Whole Blood; Female; Heart Ar

1971
[Cardiac reanimation in poisoning].
    Semaine therapeutique, 1967, Volume: 43, Issue:3

    Topics: Aconitum; Arrhythmias, Cardiac; Digitalis Glycosides; Heart Arrest; Humans; Imipramine; Quinidine; T

1967
Cardiac arrest and arrhythmias due to self-poisoning with imipramine.
    Anaesthesia, 1969, Volume: 24, Issue:1

    Topics: Adult; Antidotes; Arrhythmias, Cardiac; Female; Heart Arrest; Humans; Imipramine; Pyridostigmine Bro

1969
Fatal imipramine overdosage.
    The Medical journal of Australia, 1966, May-14, Volume: 1, Issue:20

    Topics: Adult; Female; Heart Arrest; Humans; Imipramine; Neurotic Disorders; Respiratory Insufficiency; Seiz

1966