imipramine has been researched along with Asymmetric Diabetic Proximal Motor Neuropathy in 17 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twelve patients with severe, painful diabetic neuropathy in the lower extremities were treated with imipramine and placebo in a fixed-dose, double-blind, crossover study of five plus five weeks." | 9.05 | Imipramine treatment of painful diabetic neuropathy. ( Frøland, A; Gram, LF; Kvinesdal, B; Molin, J, 1984) |
| "Twelve patients with severe, painful diabetic neuropathy in the lower extremities were treated with imipramine and placebo in a fixed-dose, double-blind, crossover study of five plus five weeks." | 5.05 | Imipramine treatment of painful diabetic neuropathy. ( Frøland, A; Gram, LF; Kvinesdal, B; Molin, J, 1984) |
| "Mianserin was given in the fixed dosage of 60 mg per day, whereas the dose of imipramine was adjusted to yield the optimal plasma concentration of imipramine plus desipramine of 400-600 nmol." | 2.67 | Lack of effect of mianserin on the symptoms of diabetic neuropathy. ( Beck-Nielsen, H; Brøsen, K; Gram, LF; Grodum, E; Sindrup, SH; Skjold, T; Tuxen, C, 1992) |
| "Paroxetine was given as a fixed dose of 40 mg/day, while the dose of imipramine was adjusted to yield optimal plasma levels of imipramine plus desipramine of 400-600 nM." | 2.67 | The selective serotonin reuptake inhibitor paroxetine is effective in the treatment of diabetic neuropathy symptoms. ( Brøsen, K; Eshøj, O; Gram, LF; Mogensen, EF; Sindrup, SH, 1990) |
| "The imipramine doses were changed stepwise from doses yielding plasma concentrations of imipramine plus desipramine below 150 nM, up to doses yielding therapeutic drug levels of at least 300-500 nM." | 1.28 | Nonlinear kinetics of imipramine in low and medium plasma level ranges. ( Brøsen, K; Gram, LF; Sindrup, SH, 1990) |
| "Imipramine doses were individually adjusted until doses yielded plasma concentrations of imipramine plus desipramine that were well above 400 nmol/L or until all neuropathy symptoms had vanished." | 1.28 | Concentration-response relationship in imipramine treatment of diabetic neuropathy symptoms. ( Beck-Nielsen, H; Frøland, A; Gram, LF; Sindrup, SH; Skjold, T, 1990) |
| "Erythromelalgia is a syndrome characterized by erythema, burning pain and increased skin temperature of the affected extremities." | 1.27 | Erythromelalgia associated with acute diabetic neuropathy: an unusual condition. ( Bosch, X; Esmatjes, E; Goday, A; Gomis, R; Nubiola, A; Vendrell, J; Vilardell, E, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (41.18) | 18.7374 |
| 1990's | 7 (41.18) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sindrup, SH | 8 |
| Holbech, J | 1 |
| Demant, D | 1 |
| Finnerup, NB | 1 |
| Bach, FW | 3 |
| Jensen, TS | 2 |
| Hearn, L | 1 |
| Derry, S | 1 |
| Phillips, T | 1 |
| Moore, RA | 1 |
| Wiffen, PJ | 1 |
| Madsen, C | 1 |
| Gram, LF | 10 |
| Kvinesdal, B | 3 |
| Molin, J | 3 |
| Frøland, A | 5 |
| Rubinow, DR | 1 |
| Nelson, JC | 1 |
| Pfeifer, MA | 1 |
| Ross, DR | 1 |
| Schrage, JP | 1 |
| Gelber, DA | 1 |
| Schumer, MP | 1 |
| Crain, GM | 1 |
| Markwell, SJ | 1 |
| Jung, S | 1 |
| Tuxen, C | 1 |
| Grodum, E | 1 |
| Skjold, T | 2 |
| Brøsen, K | 4 |
| Beck-Nielsen, H | 2 |
| Eshøj, O | 1 |
| Mogensen, EF | 1 |
| Naghmi, R | 1 |
| Subuhi, R | 1 |
| Young, RJ | 1 |
| Clarke, BF | 1 |
| Ejlertsen, B | 1 |
| Sindrup, EH | 1 |
| Vendrell, J | 1 |
| Nubiola, A | 1 |
| Goday, A | 1 |
| Bosch, X | 1 |
| Esmatjes, E | 1 |
| Gomis, R | 1 |
| Vilardell, E | 1 |
1 review available for imipramine and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Imipramine for neuropathic pain in adults.
Topics: Adult; Analgesics; Antidepressive Agents, Tricyclic; Diabetic Neuropathies; Humans; Imipramine; Midd | 2014 |
11 trials available for imipramine and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Impact of etiology and duration of pain on pharmacological treatment effects in painful polyneuropathy.
Topics: Adult; Aged; Anticonvulsants; Antidepressive Agents; Carbamazepine; Diabetic Neuropathies; Female; H | 2017 |
Venlafaxine versus imipramine in painful polyneuropathy: a randomized, controlled trial.
Topics: Adult; Aged; Analgesics, Non-Narcotic; Cross-Over Studies; Cyclohexanols; Diabetic Neuropathies; Dou | 2003 |
[Imipramine in the treatment of painful diabetic neuropathy of the extremities].
Topics: Adult; Aged; Clinical Trials as Topic; Diabetic Neuropathies; Double-Blind Method; Female; Humans; I | 1983 |
Imipramine treatment of painful diabetic neuropathy.
Topics: Adult; Aged; Clinical Trials as Topic; Diabetic Neuropathies; Double-Blind Method; Female; Humans; I | 1984 |
A highly successful and novel model for treatment of chronic painful diabetic peripheral neuropathy.
Topics: Analgesics; Capsaicin; Diabetic Neuropathies; Exercise Therapy; Female; Glycated Hemoglobin; Humans; | 1993 |
Plasma beta-endorphin is not affected by treatment with imipramine or paroxetine in patients with diabetic neuropathy symptoms.
Topics: Adult; Aged; Antidepressive Agents; beta-Endorphin; Diabetic Neuropathies; Double-Blind Method; Fema | 1992 |
Lack of effect of mianserin on the symptoms of diabetic neuropathy.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Desipramine; Diabetic Neuropathies; Double-Blind Meth | 1992 |
The selective serotonin reuptake inhibitor paroxetine is effective in the treatment of diabetic neuropathy symptoms.
Topics: Depression; Desipramine; Diabetic Neuropathies; Humans; Imipramine; Nervous System; Osmolar Concentr | 1990 |
Pain relief in diabetic neuropathy: the effectiveness of imipramine and related drugs.
Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Clonazepam; Diabetic Neuropathies; Double-Blin | 1985 |
Imipramine treatment in diabetic neuropathy: relief of subjective symptoms without changes in peripheral and autonomic nerve function.
Topics: Adult; Autonomic Nervous System; Diabetic Neuropathies; Female; Humans; Imipramine; Male; Middle Age | 1989 |
Antidepressive agents in the treatment of diabetic neuropathy.
Topics: Adult; Aged; Clinical Trials as Topic; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Double-Blin | 1985 |
5 other studies available for imipramine and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Tricyclic exacerbation of undiagnosed diabetic uropathy.
Topics: Aged; Delusions; Depressive Disorder; Diabetes Complications; Diabetes Mellitus; Diabetic Neuropathi | 1982 |
Nonlinear kinetics of imipramine in low and medium plasma level ranges.
Topics: Adult; Aged; Desipramine; Diabetic Neuropathies; Female; Half-Life; Homeostasis; Humans; Imipramine; | 1990 |
Concentration-response relationship in imipramine treatment of diabetic neuropathy symptoms.
Topics: Adult; Desipramine; Diabetic Neuropathies; Dose-Response Relationship, Drug; Female; Humans; Imipram | 1990 |
Diabetic oculomotor mononeuropathy: involvement of pupillomotor fibres with slow resolution.
Topics: Blood Glucose; Diabetes Mellitus; Diabetic Neuropathies; Humans; Imipramine; Insulin; Middle Aged; O | 1990 |
Erythromelalgia associated with acute diabetic neuropathy: an unusual condition.
Topics: Acute Disease; Adult; Carbamazepine; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Erythromelalg | 1988 |