imipramine has been researched along with As If Personality in 33 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ninety-three patients with panic disorder and mild or no agoraphobia were treated for their panic disorder by using either 11 sessions of individual cognitive-behavior therapy or imipramine." | 5.08 | Effects of panic disorder treatments on personality disorder characteristics. ( Barlow, DH; Gorman, JM; Hershberger, D; Hofmann, SG; Patterson, M; Shear, MK; Woods, SW, 1998) |
| " Among the more important recent discoveries are the efficacy of the tricyclic antidepressants for panic disorder and agoraphobia with panic attacks; the use of the monoamine oxidase inhibitors for the above disorders and for atypical depression and hysteroid dysphoria; the use of propranolol for anxiety disorders and for uncontrollable violent outbursts; the antianxiety and antipanic effects of clonidine; and the usefulness of lithium in treating schizophrenia and schizoaffective disorder and for emotionally unstable character disorders." | 4.76 | Newer uses for older psychotropic medications. ( Liebowitz, MR, 1982) |
| "Although the mean duration of dysthymia was about 30 years and almost half of the patients had previous episodes of major depression, only 41." | 2.68 | The undertreatment of dysthymia. ( Davidson, J; Halbreich, U; Koran, L; Pearlstein, T; Shelton, RC; Thase, ME; Yonkers, KA, 1997) |
| "The prognosis of treated hypochondriasis is good in a substantial proportion of patients." | 1.27 | Functional somatic symptoms and hypochondriasis. A survey of empirical studies. ( Kellner, R, 1985) |
| "A subcategory of patients with borderline personality disorder (BPD) who also meet criteria for attention deficit disorder (ADD) has recently been described." | 1.27 | Use of imipramine for attention deficit disorder in a borderline patient. ( Denton, C; Satel, S; Southwick, S, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (69.70) | 18.7374 |
| 1990's | 7 (21.21) | 18.2507 |
| 2000's | 3 (9.09) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Russell, JM | 1 |
| Kornstein, SG | 1 |
| Shea, MT | 2 |
| McCullough, JP | 1 |
| Harrison, WM | 1 |
| Hirschfeld, RM | 1 |
| Keller, MB | 1 |
| Berlim, MT | 1 |
| Turecki, G | 1 |
| Snyder, S | 1 |
| Liebowitz, MR | 2 |
| Petti, TA | 1 |
| Unis, A | 1 |
| Barber, JP | 1 |
| Muenz, LR | 1 |
| Shelton, RC | 1 |
| Davidson, J | 1 |
| Yonkers, KA | 1 |
| Koran, L | 1 |
| Thase, ME | 1 |
| Pearlstein, T | 1 |
| Halbreich, U | 1 |
| Benjamin, LS | 1 |
| Hofmann, SG | 1 |
| Shear, MK | 1 |
| Barlow, DH | 1 |
| Gorman, JM | 1 |
| Hershberger, D | 1 |
| Patterson, M | 1 |
| Woods, SW | 1 |
| Zuroff, DC | 1 |
| Blatt, SJ | 1 |
| Sanislow, CA | 1 |
| Bondi, CM | 1 |
| Pilkonis, PA | 3 |
| Reich, J | 1 |
| Boyer, P | 1 |
| Guelfi, JD | 1 |
| Shopsin, B | 1 |
| Kline, NS | 1 |
| De Leo, D | 1 |
| Caneva, A | 1 |
| Marazziti, D | 1 |
| Conti, L | 1 |
| Beckham, E | 1 |
| Collins, JF | 1 |
| Elkin, I | 1 |
| Sotsky, SM | 1 |
| Docherty, JP | 1 |
| Kellner, R | 1 |
| Joffe, RT | 1 |
| Regan, JJ | 1 |
| Frank, E | 1 |
| Satel, S | 1 |
| Southwick, S | 1 |
| Denton, C | 1 |
| Winokur, G | 1 |
| Smulevich, AB | 1 |
| Vorob'ev, VIu | 1 |
| Zavidovskaia, GI | 1 |
| Lobova, EK | 1 |
| Balashova, MG | 1 |
| Klein, DF | 4 |
| Honigfeld, G | 3 |
| Feldman, S | 3 |
| Petersen, KE | 1 |
| Andersen, OO | 1 |
| Hansen, T | 1 |
| Sirois, F | 1 |
| Ossofsky, HJ | 1 |
| Glatzel, J | 1 |
| Suchenwirth, R | 1 |
| Montanini, R | 1 |
| Radzuweit, H | 1 |
| Knorr, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Randomized Controlled Trial of Electroconvulsive Therapy With Ketamine Anesthesia (Standard Therapy) and High Intensity Ketamine With Electroconvulsive Therapy Rescue for Treatment-Resistant Depression - EAST HIKER Trial[NCT03272698] | Phase 4 | 62 participants (Anticipated) | Interventional | 2017-09-01 | Recruiting | ||
| Subanesthetic Sevoflurane for Treatment-Resistant Depression: A Proof-of-Concept Trial[NCT05008939] | 15 participants (Anticipated) | Interventional | 2021-08-31 | Not yet recruiting | |||
| Computational Psychiatric Approach for Prognosis of Medication-Resistant Depression[NCT04189939] | 144 participants (Anticipated) | Observational | 2020-03-09 | Recruiting | |||
| Clinical Effects of Electroconvulsive Therapy in Severe Depression and Concomitant Changes in Cerebral Glucose Metabolism - an Exploratory Study[NCT01514435] | 13 participants (Actual) | Interventional | 2006-05-31 | Completed | |||
| Efficacy of Dynamic Therapy Versus Selective Serotonin Reuptake Inhibitor for Depression[NCT00043550] | Phase 3 | 156 participants (Actual) | Interventional | 2001-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Hamilton Rating Scale for Depression (HRSD) (Hamilton, 1960). We used the 17-item version of the 27-item HRSD, a measure of depression severity. The Structured Interview Guide was used to conduct the interviews (SIGH-D; Williams, 1988). The reliability and validity of the HRSD are well documented (Rabkin & Klein, 1987). Interjudge reliability as assessed by interclass correlations was .92 in our sample. Total 17-item scores could range from 17-48 with higher scores indicating greater distress. (NCT00043550)
Timeframe: symptoms assessed during past 7 days, measure taken at baseline, week 8 and week 16
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Initial HRSD-17 | Mid-treatment HRSD-17 | LOCF HRSD-17 | |
| 1 Sertraline | 19.0 | 13.9 | 14.2 |
| 2 Supportive-expressive Psychotherapy | 19.9 | 12.5 | 14.5 |
| 3 Pill Placebo | 19.4 | 12.7 | 14.3 |
5 reviews available for imipramine and As If Personality
| Article | Year |
|---|---|
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
Definition, assessment, and staging of treatment-resistant refractory major depression: a review of current concepts and methods.
Topics: Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disorder, Major; Dose-Response Relationshi | 2007 |
The interaction of psychopharmacology and psychoanalysis in the borderline patient.
Topics: Affect; Anger; Antipsychotic Agents; Borderline Personality Disorder; Chlorpromazine; Clinical Trial | 1980 |
Newer uses for older psychotropic medications.
Topics: Adrenergic beta-Antagonists; Agoraphobia; Anxiety Disorders; Bipolar Disorder; Clonidine; Depressive | 1982 |
Special feature: personality disorders: models for treatment and strategies for treatment development.
Topics: Adult; Behavior Therapy; Clinical Protocols; Clinical Trials as Topic; Cognitive Behavioral Therapy; | 1997 |
Is borderline a distinct entity?
Topics: Adjustment Disorders; Adoption; Affective Symptoms; Chlorpromazine; Clinical Trials as Topic; Diagno | 1979 |
13 trials available for imipramine and As If Personality
| Article | Year |
|---|---|
Chronic depression and comorbid personality disorders: response to sertraline versus imipramine.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Chronic Disease; Comorbidity; Depressive Disorder; Do | 2003 |
The interaction of psychopharmacology and psychoanalysis in the borderline patient.
Topics: Affect; Anger; Antipsychotic Agents; Borderline Personality Disorder; Chlorpromazine; Clinical Trial | 1980 |
Imipramine treatment of borderline children: case reports with a controlled study.
Topics: Borderline Personality Disorder; Child; Clinical Trials as Topic; Double-Blind Method; Female; Human | 1981 |
The role of avoidance and obsessiveness in matching patients to cognitive and interpersonal psychotherapy: empirical findings from the treatment for depression collaborative research program.
Topics: Adult; Antidepressive Agents, Tricyclic; Avoidance Learning; Cognitive Behavioral Therapy; Combined | 1996 |
The undertreatment of dysthymia.
Topics: 1-Naphthylamine; Adult; Age of Onset; Aged; Ambulatory Care; Antidepressive Agents; Comorbidity; Dys | 1997 |
Effects of panic disorder treatments on personality disorder characteristics.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Cognitive Behavioral Therapy; Female; Follow-Up Studi | 1998 |
Vulnerability to depression: reexamining state dependence and relative stability.
Topics: Adult; Attitude; Chi-Square Distribution; Cognitive Behavioral Therapy; Depressive Disorder; Disease | 1999 |
Is borderline a distinct entity?
Topics: Adjustment Disorders; Adoption; Affective Symptoms; Chlorpromazine; Clinical Trials as Topic; Diagno | 1979 |
Personality disorders and treatment outcome in the NIMH Treatment of Depression Collaborative Research Program.
Topics: Adult; Ambulatory Care; Depressive Disorder; Female; Humans; Imipramine; Male; National Institute of | 1990 |
Mode of action and relative value of imipramine and similar drugs in the treatment of nocturnal enuresis.
Topics: Adolescent; Benzene Derivatives; Child; Child, Preschool; Clinical Trials as Topic; Enuresis; Female | 1974 |
[Clinical experiences with a new thymoleptic].
Topics: Amitriptyline; Antidepressive Agents; Clinical Trials as Topic; Depression; Female; Humans; Imiprami | 1967 |
Prediction of drug effect by diagnostic decision tree.
Topics: Anxiety; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Depression; Factor Analysis, St | 1968 |
Psychiatric diagnosis and a typology of clinical drug effects.
Topics: Affective Symptoms; Analysis of Variance; Anger; Bipolar Disorder; Chlorpromazine; Clinical Trials a | 1968 |
17 other studies available for imipramine and As If Personality
| Article | Year |
|---|---|
Personality change after treatment.
Topics: Double-Blind Method; Dysthymic Disorder; Humans; Imipramine; Personality Assessment; Personality Dis | 2002 |
[Somatic disorders and depressive states].
Topics: Amitriptyline; Antidepressive Agents; Cardiovascular Diseases; Depression; Disease; Drug Hypersensit | 1978 |
Monoamine oxidase inhibitors: potential for drug abuse.
Topics: Amphetamines; Drug Tolerance; Feeding Behavior; Humans; Imipramine; Male; Middle Aged; Monoamine Oxi | 1976 |
Platelet imipramine binding in intensive care unit suicidal patients.
Topics: Adult; Blood Platelets; Carrier Proteins; Depressive Disorder; Female; Humans; Imipramine; Intensive | 1991 |
Functional somatic symptoms and hypochondriasis. A survey of empirical studies.
Topics: Anti-Anxiety Agents; Attitude to Health; Benzodiazepines; Conditioning, Psychological; Culture; Diag | 1985 |
Personality and depression.
Topics: Adult; Depressive Disorder; Desipramine; Female; Humans; Imipramine; Male; Manuals as Topic; Persona | 1988 |
Personality pathology in recurrent depression: nature, prevalence, and relationship to treatment response.
Topics: Adult; Aged; Depressive Disorder; Female; Humans; Imipramine; Male; Middle Aged; Outcome and Process | 1988 |
Use of imipramine for attention deficit disorder in a borderline patient.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder; Humans; Imipr | 1988 |
Genetic and clinical factors associated with course in depression. Contributions to genetic aspects.
Topics: Alcoholism; Bipolar Disorder; Chlorpromazine; Chronic Disease; Depression; Female; Humans; Imipramin | 1974 |
[Problems of differentiated thymoleptic therapy in phasic depressions].
Topics: Adolescent; Adult; Amitriptyline; Anthracenes; Antidepressive Agents; Azocines; Benzoates; Benzofura | 1974 |
Prediction of drug effect in personality disorders.
Topics: Affective Symptoms; Chlorpromazine; Depression; Diagnosis, Computer-Assisted; Evaluation Studies as | 1973 |
[Natural history of enuresis].
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Conditioning, Psychological; Enuresis; Fema | 1974 |
Amenorrhea in endogenous depression.
Topics: Adolescent; Adult; Amenorrhea; Bipolar Disorder; Depression; Female; Humans; Imipramine; Lithium; Pe | 1974 |
[Effect of thymoleptica in the drawing test].
Topics: Amitriptyline; Antidepressive Agents; Desipramine; Female; Humans; Imipramine; Middle Aged; Personal | 1967 |
[Neuropsychiatric aspects of male sterility].
Topics: Amitriptyline; Depression; Dibenzazepines; Frustration; Humans; Imipramine; Infertility, Male; Male; | 1972 |
The reliability of a decision tree technique applied to psychiatric diagnosis.
Topics: Affective Symptoms; Chlorpromazine; Decision Making; Diagnosis, Differential; Factor Analysis, Stati | 1972 |
[Influencing of biological and immunologic pregnancy reactions by psychotropic drugs].
Topics: Adolescent; Adult; Aged; Butyrophenones; Chlorpromazine; Dementia; Depressive Disorder, Major; Dysau | 1969 |