imipramine has been researched along with Arrhythmias, Cardiac in 100 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Arrhythmias, Cardiac: Any disturbances of the normal rhythmic beating of the heart or MYOCARDIAL CONTRACTION. Cardiac arrhythmias can be classified by the abnormalities in HEART RATE, disorders of electrical impulse generation, or impulse conduction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The reactivity of 40 panic disorder patients on mental arithmetic, cold pressor, and 5% CO2 inhalation stressors was tested before and after 8 weeks of treatment with imipramine, alprazolam, or placebo." | 9.07 | Imipramine and alprazolam effects on stress test reactivity in panic disorder. ( Agras, WS; Ehlers, A; Haddad, JM; Maddock, RJ; Margraf, J; Roth, WT; Taylor, CB, 1992) |
| " After a short period of time, she became unconscious and experienced hypotension and refractory arrhythmia, finally being diagnosed with imipramine poisoning." | 7.91 | Refractory Arrhythmias in a Young Patient Poisoned by Imipramine. ( Azdaki, N; Mehrpour, O; Nakhaee, S; Zamani, N, 2019) |
| "The potential antiarrhythmic activity of imipramine against ventricular arrhythmias induced by coronary artery ligation in rats has been investigated and compared with procainamide." | 7.68 | Suppression of ventricular arrhythmias resulting from acute coronary artery ligation in rat by imipramine. ( Alhaider, AA; Bashandy, AM; el-Mahdy, SA; Mahgoub, AA, 1990) |
| "Sodium bicarbonate has been recommended for the treatment of arrhythmias induced by tricyclic antidepressants." | 7.67 | Use of sodium bicarbonate to treat tricyclic antidepressant-induced arrhythmias in a patient with alkalosis. ( Hall, KW; Molloy, DW; Penner, SB; Rabson, J, 1984) |
| "The incidence of halothane-epinephrine arrhythmias increases after the short-term administration of imipramine, probably because of enhanced noradrenergic transmission." | 7.67 | Halothane-epinephrine arrhythmias and adrenergic responsiveness after chronic imipramine administration in dogs. ( Maze, M; Smith, CM; Spiss, CK, 1984) |
| "Imipramine is an effective antiarrhythmic agent against ventricular arrhythmias and complex features of ventricular premature depolarizations at plasma concentrations ranging from 100 to 400 ng per ml." | 7.67 | Cardiac and antiarrhythmic effects of imipramine in patients with ventricular arrhythmias. ( Giardina, EG, 1984) |
| " During a double-blind drug and dose selection phase, investigators were permitted to change drug or dosage to achieve greater than or equal to 70% suppression in VPC frequency and greater than 90% suppression of runs of VPC with the exception of patients assigned to placebo, who continued receiving it." | 6.66 | Effects of encainide, flecainide, imipramine and moricizine on ventricular arrhythmias during the year after acute myocardial infarction: the CAPS. ( , 1988) |
| "Physostigmine is a commonly used therapy for the anticholinergic manifestations of tricyclic antidepressant (TCA) overdose." | 5.26 | Asystole complicating physostigmine treatment of tricyclic antidepressant overdose. ( Pentel, P; Peterson, CD, 1980) |
| "The reactivity of 40 panic disorder patients on mental arithmetic, cold pressor, and 5% CO2 inhalation stressors was tested before and after 8 weeks of treatment with imipramine, alprazolam, or placebo." | 5.07 | Imipramine and alprazolam effects on stress test reactivity in panic disorder. ( Agras, WS; Ehlers, A; Haddad, JM; Maddock, RJ; Margraf, J; Roth, WT; Taylor, CB, 1992) |
| " After a short period of time, she became unconscious and experienced hypotension and refractory arrhythmia, finally being diagnosed with imipramine poisoning." | 3.91 | Refractory Arrhythmias in a Young Patient Poisoned by Imipramine. ( Azdaki, N; Mehrpour, O; Nakhaee, S; Zamani, N, 2019) |
| "In experiments in white mice and rats the antidepressants pyrazidol (pirlindole), moclobemide and especially tetrindole possess anticalcium activity in tests of calcium chloride-induced lethality in mice and arrhythmia in rats." | 3.68 | [Anticalcium activity of several antidepressive agents]. ( Andreeva, NI; Golovina, SM; Mashkovskiĭ, MD; Rumiantsev, EA, 1992) |
| "The potential antiarrhythmic activity of imipramine against ventricular arrhythmias induced by coronary artery ligation in rats has been investigated and compared with procainamide." | 3.68 | Suppression of ventricular arrhythmias resulting from acute coronary artery ligation in rat by imipramine. ( Alhaider, AA; Bashandy, AM; el-Mahdy, SA; Mahgoub, AA, 1990) |
| "Sodium bicarbonate has been recommended for the treatment of arrhythmias induced by tricyclic antidepressants." | 3.67 | Use of sodium bicarbonate to treat tricyclic antidepressant-induced arrhythmias in a patient with alkalosis. ( Hall, KW; Molloy, DW; Penner, SB; Rabson, J, 1984) |
| "The incidence of halothane-epinephrine arrhythmias increases after the short-term administration of imipramine, probably because of enhanced noradrenergic transmission." | 3.67 | Halothane-epinephrine arrhythmias and adrenergic responsiveness after chronic imipramine administration in dogs. ( Maze, M; Smith, CM; Spiss, CK, 1984) |
| "Imipramine is an effective antiarrhythmic agent against ventricular arrhythmias and complex features of ventricular premature depolarizations at plasma concentrations ranging from 100 to 400 ng per ml." | 3.67 | Cardiac and antiarrhythmic effects of imipramine in patients with ventricular arrhythmias. ( Giardina, EG, 1984) |
| " In 1 patient, acute myocardial infarction developed after two 10-mg doses of nortriptyline." | 3.66 | Cardiovascular side effects of long-term therapy with tricyclic antidepressants in the aged. ( Oei, LS; Rodstein, M, 1979) |
| "The electrocardiographic effects of imipramine hydrochloride at therapeutic plasma concentrations were determined in 44 depressed patients during a 6-week clinical outcome study of depression." | 3.66 | The electrocardiographic and antiarrhythmic effects of imipramine hydrochloride at therapeutic plasma concentrations. ( Bigger, JT; Giardina, EG; Glassman, AH; Kantor, SJ; Perel, JM, 1979) |
| "Enuresis is a common problem often treated effectively with imipramine hydrochloride." | 3.66 | Treatment of imipramine overdose in children. ( Cromie, WJ; Greene, AS, 1981) |
| "The antiarrhythmic plasma-concentration range of imipramine with desmethylimipramine was determined in 15 cardiac patients with ventricular arrhythmias." | 3.66 | Antiarrhythmic plasma-concentration range of imipramine against ventricular premature depolarizations. ( Alchevsky, D; Bigger, JT; Brem, R; Giardina, EG; Louie, M, 1983) |
| "The authors studied the monthly electrocardiographic tracings of 27 children with normal cardiovascular function receiving imipramine therapy for enuresis." | 3.65 | Electrocardiographic monitoring of enuretic children receiving therapeutic doses of imipramine. ( Martin, GI; Zaug, PJ, 1975) |
| "Clinical experience has firmly established the usefulness of imipramine in the management of enuresis." | 3.65 | Imipramine toxicity. ( Rohner, TJ; Sanford, EJ, 1975) |
| " Cardiac arrhythmias induced in children by amitriptyline and imipramine are prominent and dangerous." | 3.65 | Amitriptyline and imipramine poisoning in children. ( Goel, KM; Shanks, RA, 1974) |
| " During a double-blind drug and dose selection phase, investigators were permitted to change drug or dosage to achieve greater than or equal to 70% suppression in VPC frequency and greater than 90% suppression of runs of VPC with the exception of patients assigned to placebo, who continued receiving it." | 2.66 | Effects of encainide, flecainide, imipramine and moricizine on ventricular arrhythmias during the year after acute myocardial infarction: the CAPS. ( , 1988) |
| "Treatment with imipramine and doxepin, but not placebo, was associated with significant improvement (P less than 0." | 2.65 | Cardiovascular effects of tricyclic antidepressants in depressed patients with chronic heart disease. ( Barnes, RF; Caldwell, JH; Gumbrecht, G; Raskind, MA; Ritchie, JL; Veith, RC, 1982) |
| "With imipramine there was potentiation of the pressor effects of phenylephrine (2-3 fold), noradrenaline (4-8 fold), and adrenaline (2-4 fold); there were dysrhythmias during adrenaline infusions, but no noticeable or consistent changes in response to isoprenaline." | 2.64 | Interactions between sympathomimetic amines and antidepressant agents in man. ( Barar, FS; Benedikter, LT; Boakes, AJ; Laurence, DR; Prichard, BN; Teoh, PC, 1973) |
| "Imipramine has been surpassed by newer antidepressants for the treatment of depression in the past decade." | 1.42 | Neurologic and Cardiovascular Complications in Pediatric Life Threatening Imipramine Poisoning. ( Cheung, KL; Fung, CK; Hon, KL; Lee, VW; Leung, AK; Wong, W, 2015) |
| "In the anesthetized guinea pig, arrhythmias are induced by a slow intravenous infusion of digoxin, which provokes extrasystoles, ventricular tachyarrhythmias, and ultimately cardiac arrest." | 1.35 | Models of cardiovascular disease: measurement of arrhythmogenic/antiarrhythmic activity in the guinea pig. ( Guillaume, P; Lacroix, P; Provost, D, 2009) |
| "However, the incidence of cardiac dysrhythmia was increased after the use of acetazolamide." | 1.31 | [A case of potassium-sensitive periodic paralysis with cardiac dysrhythmia controlled with imipramine and acetazolamide]. ( Endo, T; Fujimori, J; Itoyama, Y; Onodera, H; Shiga, Y; Takahashi, T; Takeda, A; Tateyama, M; Yoshimoto, T, 2001) |
| "This case study describes the sudden death of an additional child (8 years 9 months old, 29 kg in weight) treated with a tricyclic antidepressant, imipramine (100 mg orally, twice daily), and dextroamphetamine (10 mg orally every morning)." | 1.31 | Sudden death of a child treated with imipramine. Case study. ( Varley, CK, 2000) |
| "No significant arrhythmias or tachycardias were observed." | 1.29 | ECG changes in pediatric patients on tricyclic antidepressants, desipramine, and imipramine. ( Giuffre, RM; Johnson, A; O'Malley, K, 1996) |
| "The hemodynamic, cardiographic, and initial pharmacokinetic characteristics of the de novo administration of the 2-hydroxymetabolite (2-OH-IMI) of imipramine (IMI), compared with its parent was studied in a swine preparation." | 1.28 | Imipramine and 2-hydroxyimipramine: comparative cardiotoxicity and pharmacokinetics in swine. ( Perel, JM; Pollock, BG, 1992) |
| "Amineptine, however, was ineffective in preventing reperfusion arrhythmias even in a high concentration, this agent did not decrease heart rate." | 1.27 | Comparison of the effect of antidepressant drugs on arrhythmias in the isolated rat heart subjected to myocardial ischaemia and reperfusion. ( Bril, A; Rochette, L, 1987) |
| "Imipramine was infused at 1 mg/kg/min until cardiac failure and vascular collapse terminated the experiment at 21 +/- 2." | 1.27 | Treatment of haemodynamic and electrocardiographic side-effects resulting from imipramine toxicity in rats and dogs. ( Fiedler, VB; Göbel, H; Kettenbach, B; Nitz, RE, 1985) |
| "Imipramine was less arrhythmogenic and caused less fall in blood pressure for a given dose than amitriptyline or doxepin." | 1.26 | Comparison of the cardiovascular toxicity of three tricyclic antidepressant drugs: imipramine, amitriptyline, and doxepin. ( Brown, TC; Leversha, A, 1979) |
| "3." | 1.26 | The relative toxicity of amitriptyline, imipramine, maprotiline and mianserin in rabbits in vivo. ( Hughes, IE; Radwan, S, 1979) |
| "We evaluated the ability of the Lown arrhythmia grading system to predict death in 400 patients who were convalescing from acute myocardial infarction." | 1.26 | Shortcomings of the Lown grading system for observational or experimental studies in ischemic heart disease. ( Bigger, JT; Weld, FM, 1980) |
| "Physostigmine is a commonly used therapy for the anticholinergic manifestations of tricyclic antidepressant (TCA) overdose." | 1.26 | Asystole complicating physostigmine treatment of tricyclic antidepressant overdose. ( Pentel, P; Peterson, CD, 1980) |
| "Five of the 10 patients had arrhythmias and two of these died." | 1.25 | Cardiac abnormalities in poisoning with tricyclic antidepressants. ( Beattie, RR; Freeman, JW; Mundy, GR; Ryan, C, 1969) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 83 (83.00) | 18.7374 |
| 1990's | 8 (8.00) | 18.2507 |
| 2000's | 6 (6.00) | 29.6817 |
| 2010's | 3 (3.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, L | 1 |
| Sun, H | 1 |
| Azdaki, N | 1 |
| Nakhaee, S | 1 |
| Zamani, N | 1 |
| Mehrpour, O | 1 |
| Hon, KL | 1 |
| Fung, CK | 1 |
| Lee, VW | 1 |
| Cheung, KL | 1 |
| Wong, W | 1 |
| Leung, AK | 1 |
| Sert, A | 1 |
| Aypar, E | 1 |
| Odabas, D | 1 |
| Aygul, MU | 1 |
| Guillaume, P | 1 |
| Provost, D | 1 |
| Lacroix, P | 1 |
| OSBORNE, MW | 1 |
| WINBURY, MM | 1 |
| CHEIKHZADEH, A | 1 |
| SCHOLER, H | 1 |
| Greene, AS | 1 |
| Cromie, WJ | 1 |
| Dilsaver, SC | 1 |
| Greden, JF | 1 |
| Molloy, DW | 1 |
| Penner, SB | 1 |
| Rabson, J | 1 |
| Hall, KW | 1 |
| Pratt, CM | 1 |
| Luck, JC | 1 |
| Mann, DE | 1 |
| Wyndham, CR | 1 |
| Spiss, CK | 1 |
| Smith, CM | 1 |
| Maze, M | 1 |
| Giardina, EG | 4 |
| Guerrero Sanz, JE | 1 |
| del Castillo Rueda, A | 1 |
| Escalante Cobo, JL | 1 |
| Grau Carmona, T | 1 |
| Orr, DA | 1 |
| Bramble, MG | 1 |
| Louie, M | 1 |
| Bigger, JT | 5 |
| Brem, R | 1 |
| Alchevsky, D | 1 |
| Pentel, P | 1 |
| Peterson, CD | 1 |
| Veith, RC | 1 |
| Raskind, MA | 1 |
| Caldwell, JH | 1 |
| Barnes, RF | 1 |
| Gumbrecht, G | 1 |
| Ritchie, JL | 1 |
| Marshall, JB | 1 |
| Forker, AD | 1 |
| Weld, FM | 2 |
| Thase, ME | 1 |
| Perel, JM | 3 |
| Ulrichsen, A | 1 |
| Sandvik, A | 1 |
| Stefansen, D | 1 |
| Dubuc, M | 1 |
| Friborg, J | 1 |
| Houde, M | 1 |
| Laplante, L | 1 |
| Boisvert, D | 1 |
| Chouinard, G | 1 |
| Johnson, A | 1 |
| Giuffre, RM | 1 |
| O'Malley, K | 2 |
| Robert, E | 1 |
| Bruelle, P | 1 |
| de La Coussaye, JE | 1 |
| Juan, JM | 1 |
| Brugada, J | 1 |
| Peray, P | 1 |
| Dauzat, M | 1 |
| Eledjam, JJ | 1 |
| Naccarelli, GV | 1 |
| Dougherty, AH | 1 |
| Wolbrette, D | 1 |
| Wiggins, S | 1 |
| Varley, CK | 1 |
| Endo, T | 1 |
| Takeda, A | 1 |
| Shiga, Y | 1 |
| Fujimori, J | 1 |
| Takahashi, T | 1 |
| Tateyama, M | 1 |
| Onodera, H | 1 |
| Itoyama, Y | 1 |
| Yoshimoto, T | 1 |
| Ohtani, H | 1 |
| Odagiri, Y | 1 |
| Sato, H | 1 |
| Sawada, Y | 1 |
| Iga, T | 1 |
| Kishi, M | 1 |
| Kurihara, T | 1 |
| Rodstein, M | 1 |
| Oei, LS | 1 |
| Edwards, RP | 1 |
| Miller, RD | 1 |
| Roizen, MF | 1 |
| Ham, J | 1 |
| Way, WL | 1 |
| Lake, CR | 1 |
| Roderick, L | 1 |
| Brown, TC | 3 |
| Leversha, A | 1 |
| Glassman, AH | 1 |
| Kantor, SJ | 1 |
| Glisson, SN | 1 |
| El-Etr, AA | 1 |
| Hughes, IE | 1 |
| Radwan, S | 1 |
| Baum, T | 2 |
| Peters, JR | 1 |
| Butz, F | 1 |
| Much, DR | 1 |
| Wright, SP | 1 |
| Israël, C | 1 |
| Gallez, A | 1 |
| Dabrowski, A | 1 |
| van de Ree, JK | 1 |
| Zimmerman, AN | 1 |
| van Heijst, AN | 1 |
| Martin, GI | 2 |
| Zaug, PJ | 2 |
| Ramanathan, KB | 1 |
| Davidson, C | 1 |
| Rohner, TJ | 1 |
| Sanford, EJ | 1 |
| Biamino, G | 1 |
| Fenner, H | 1 |
| Schüren, KP | 1 |
| Neye, J | 1 |
| Ramdohr, B | 1 |
| Lohmann, RW | 1 |
| Silva, OA | 1 |
| Carvalho Lemos, JM | 1 |
| López, M | 1 |
| Pollock, BG | 1 |
| Andreeva, NI | 1 |
| Golovina, SM | 1 |
| Rumiantsev, EA | 1 |
| Mashkovskiĭ, MD | 1 |
| Roth, WT | 1 |
| Margraf, J | 1 |
| Ehlers, A | 1 |
| Haddad, JM | 1 |
| Maddock, RJ | 1 |
| Agras, WS | 1 |
| Taylor, CB | 1 |
| Tingelstad, JB | 1 |
| el-Mahdy, SA | 1 |
| Alhaider, AA | 1 |
| Mahgoub, AA | 1 |
| Bashandy, AM | 1 |
| Czartorysky, B | 1 |
| Harding, J | 1 |
| Bril, A | 1 |
| Rochette, L | 1 |
| Mahapatra, RK | 1 |
| Paul, SK | 1 |
| Mahapatra, D | 1 |
| Winter, S | 1 |
| Fisch, C | 1 |
| Johnson, LL | 1 |
| Vita, J | 1 |
| Brem, RF | 1 |
| Muskin, PR | 1 |
| Gould, RJ | 1 |
| Steeg, CN | 1 |
| Eastwood, AB | 1 |
| Penn, AS | 1 |
| Rowland, LP | 1 |
| De Vivo, DC | 1 |
| Fiedler, VB | 1 |
| Kettenbach, B | 1 |
| Göbel, H | 1 |
| Nitz, RE | 1 |
| Moir, DC | 1 |
| Cornwell, WB | 1 |
| Dingwall-Fordyce, I | 1 |
| Crooks, J | 1 |
| Turnbull, MJ | 1 |
| Weir, RD | 1 |
| Rumack, BH | 1 |
| Anderson, RJ | 1 |
| Wolfe, R | 1 |
| Fletcher, EC | 1 |
| Vestal, BK | 1 |
| Kośmider, S | 1 |
| Smolarz, W | 1 |
| Boari, C | 1 |
| Raffi, GB | 1 |
| Orlando, E | 1 |
| Nĕmec, J | 1 |
| Rysánek, K | 1 |
| Rotrekl, J | 1 |
| Homola, D | 1 |
| Náhunek, K | 1 |
| Rodová, A | 1 |
| Svestka, J | 1 |
| Srnová, V | 1 |
| Boakes, AJ | 1 |
| Laurence, DR | 1 |
| Teoh, PC | 1 |
| Barar, FS | 1 |
| Benedikter, LT | 1 |
| Prichard, BN | 1 |
| Kanarek, KS | 1 |
| Thomson, PD | 1 |
| Levin, SE | 1 |
| Barker, GA | 1 |
| Dunlop, ME | 1 |
| Loughnan, PM | 1 |
| Filias, N | 1 |
| Jornod, J | 1 |
| Goel, KM | 1 |
| Shanks, RA | 1 |
| Langslet, A | 1 |
| Ebert, MH | 1 |
| Shader, RI | 1 |
| Vernier, VG | 1 |
| Harmon, JB | 1 |
| Stump, JM | 1 |
| Lynes, TE | 1 |
| Marvel, JP | 1 |
| Smith, DH | 1 |
| Duke, M | 1 |
| Moccetti, T | 3 |
| Lichtlen, P | 3 |
| Casaccia, M | 1 |
| Halter, J | 1 |
| Mohr, P | 1 |
| Sedal, L | 1 |
| Korman, MG | 1 |
| Williams, PO | 1 |
| Mushin, G | 1 |
| Eckfeld, DK | 1 |
| Shropshire, AT | 1 |
| Rowles, G | 1 |
| Varner, LL | 1 |
| Dwyer, ME | 1 |
| Stocks, JG | 1 |
| Fouron, JC | 1 |
| Chicoine, R | 1 |
| Bauditz, W | 2 |
| Bartelheimer, HK | 2 |
| Schmitt, H | 1 |
| Cheymol, G | 1 |
| Gilbert, JC | 1 |
| Viana, AP | 1 |
| Osswald, W | 1 |
| Noto, R | 1 |
| Robert, J | 1 |
| Hanote, P | 1 |
| Albert, H | 1 |
| Meier, E | 1 |
| Imbach, P | 1 |
| Gaultier, M | 1 |
| Potter, M | 1 |
| Sagardiluz, J | 1 |
| Clèdes, J | 1 |
| Potaux, L | 1 |
| Favarel-Garrigues, JC | 1 |
| Sacks, MH | 1 |
| Bonforte, RJ | 1 |
| Laser, RP | 1 |
| Dimich, I | 1 |
| Bismuth, C | 1 |
| Bodin, F | 1 |
| Pebay-Peroula, F | 1 |
| Frejaville, JP | 1 |
| Pearson, JD | 1 |
| Jones, ES | 1 |
| Gabbe, DM | 1 |
| Freeman, JW | 1 |
| Mundy, GR | 1 |
| Beattie, RR | 1 |
| Ryan, C | 1 |
| Mazur, M | 1 |
| Mazurowa, A | 1 |
| Szadowska, A | 1 |
| Szmigielski, A | 1 |
| Fekete, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000504] | Phase 2 | 0 participants | Interventional | 1982-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for imipramine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Antidepressant withdrawal phenomena.
Topics: Adult; Amitriptyline; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; | 1984 |
Investigational antiarrhythmic drugs for the treatment of ventricular rhythm disturbances.
Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Encainide; Flecainide | 1984 |
Cardiovascular effects of tricyclic antidepressant drugs: therapeutic usage, overdose, and management of complications.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular S | 1982 |
Drugs and sudden cardiac death.
Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Coronary Disease; Death, Sudden; Diet Fads; | 1982 |
[Periodic paralysis with cardiac arrhythmia(Andersen's syndrome)].
Topics: Acetazolamide; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbonic Anhydrase Inhibitors; Diagno | 2001 |
Cardiovascular effects of psychotropic drugs.
Topics: Antidepressive Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiovascular System; Humans; Hypotens | 1969 |
6 trials available for imipramine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Cardiovascular effects of tricyclic antidepressants in depressed patients with chronic heart disease.
Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Blood Pressure; Chronic Disease | 1982 |
Imipramine and alprazolam effects on stress test reactivity in panic disorder.
Topics: Adult; Alprazolam; Anxiety; Arrhythmias, Cardiac; Blood Pressure; Carbon Dioxide; Cold Temperature; | 1992 |
Effects of encainide, flecainide, imipramine and moricizine on ventricular arrhythmias during the year after acute myocardial infarction: the CAPS.
Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Metho | 1988 |
Cardiotoxicity of amitriptyline.
Topics: Acute Disease; Adult; Amitriptyline; Arrhythmias, Cardiac; Clinical Trials as Topic; Death, Sudden; | 1972 |
Mechanocardiographical comparison of the cardiotoxic effect of prothiaden and imipramine.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Dibenzothiepins; Dothiepin; Electrocardiography; Hea | 1974 |
Interactions between sympathomimetic amines and antidepressant agents in man.
Topics: Adult; Antidepressive Agents; Arrhythmias, Cardiac; Blood Pressure; Cardiovascular System; Drug Inte | 1973 |
88 other studies available for imipramine and Arrhythmias, Cardiac
| Article | Year |
|---|---|
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant | 2008 |
Refractory Arrhythmias in a Young Patient Poisoned by Imipramine.
Topics: Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiotoxicity; Elec | 2019 |
Neurologic and Cardiovascular Complications in Pediatric Life Threatening Imipramine Poisoning.
Topics: Accidents, Home; Adrenergic Uptake Inhibitors; Antidepressive Agents, Tricyclic; Arrhythmias, Cardia | 2015 |
Temporary cardiac pacemaker in the treatment of junctional rhythm and hypotension due to imipramine intoxication.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Electrocardiography; Female; Fol | 2011 |
Models of cardiovascular disease: measurement of arrhythmogenic/antiarrhythmic activity in the guinea pig.
Topics: Animal Husbandry; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Protocols; Digoxin | 2009 |
QUINDONIUM BROMIDE--SOME ASPECTS OF THE CARDIOVASCULAR PHARMACOLOGY.
Topics: Arrhythmias, Cardiac; Blood Pressure; Bromides; Cats; Dogs; Electrocardiography; Epinephrine; Guinea | 1965 |
[THE SYMPTOMATIC PICTURE OF IMIPRAMINE TOXICOLOGY (TOFRANIL)].
Topics: Adolescent; Arrhythmias, Cardiac; Child; Coma; Diagnosis; Heart Block; Humans; Imipramine; Neurologi | 1964 |
Treatment of imipramine overdose in children.
Topics: Adult; Arrhythmias, Cardiac; Bicarbonates; Child; Child, Preschool; Coma; Diazepam; Drug Administrat | 1981 |
Use of sodium bicarbonate to treat tricyclic antidepressant-induced arrhythmias in a patient with alkalosis.
Topics: Adult; Alkalosis; Alkalosis, Respiratory; Arrhythmias, Cardiac; Bicarbonates; Electrocardiography; F | 1984 |
Halothane-epinephrine arrhythmias and adrenergic responsiveness after chronic imipramine administration in dogs.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Desipramine; Dogs; Drug Interactions; Epinephrine; Female | 1984 |
Cardiac and antiarrhythmic effects of imipramine in patients with ventricular arrhythmias.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Heart Ventricles; Humans; Imipram | 1984 |
[Transient widening of the QRS caused by acute imipramine poisoning].
Topics: Arrhythmias, Cardiac; Electrocardiography; Female; Humans; Imipramine; Middle Aged | 1983 |
Tricyclic antidepressant poisoning and prolonged external cardiac massage during asystole.
Topics: Adult; Arrhythmias, Cardiac; Female; Heart Arrest; Heart Massage; Humans; Imipramine; Male; Prognosi | 1981 |
Antiarrhythmic plasma-concentration range of imipramine against ventricular premature depolarizations.
Topics: Adult; Aged; Arrhythmias, Cardiac; Desipramine; Dose-Response Relationship, Drug; Drug Evaluation; F | 1983 |
Asystole complicating physostigmine treatment of tricyclic antidepressant overdose.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Bradycardia; Electroca | 1980 |
Antiarrhythmic effects of tricyclic antidepressants.
Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Humans; Imipramine | 1982 |
[Treatment of cardiac arrhythmias with imipramine].
Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Humans; Imipramine; Male; Middle Aged | 1982 |
[Treatment of drug poisoning by tricyclic antidepressant agents: for or against the use of physostigmine].
Topics: Adult; Arrhythmias, Cardiac; Female; Flurazepam; Humans; Imipramine; Physostigmine | 1981 |
Rebound cardiac arrhythmia after withdrawal from imipramine: a case report.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Humans; Imipramine; Middle Aged; Substance Wit | 1981 |
Shortcomings of the Lown grading system for observational or experimental studies in ischemic heart disease.
Topics: Arrhythmias, Cardiac; Coronary Disease; Electrocardiography; Heart Ventricles; Humans; Imipramine; P | 1980 |
ECG changes in pediatric patients on tricyclic antidepressants, desipramine, and imipramine.
Topics: Adolescent; Alberta; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Attention Deficit Disor | 1996 |
Electrophysiologic and proarrhythmogenic effects of therapeutic and toxic doses of imipramine: a study with high resolution ventricular epicardial mapping in rabbit hearts.
Topics: Animals; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Electrophysiology; Heart; Imipramin | 1996 |
A critical appraisal of the cardiac arrhythmia suppression trial (CAST).
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Encainide; Flecainide; Humans; Imipramine; Moricizin | 1991 |
Sudden death of a child treated with imipramine. Case study.
Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Central Nervous System Stimulants; Child; De | 2000 |
[A case of potassium-sensitive periodic paralysis with cardiac dysrhythmia controlled with imipramine and acetazolamide].
Topics: Acetazolamide; Adolescent; Adrenergic Uptake Inhibitors; Anticonvulsants; Arrhythmias, Cardiac; Drug | 2001 |
A comparative pharmacodynamic study of the arrhythmogenicity of antidepressants, fluvoxamine and imipramine, in guinea pigs.
Topics: Animals; Antidepressive Agents; Arrhythmias, Cardiac; Electrocardiography; Fluvoxamine; Guinea Pigs; | 2001 |
Cardiovascular side effects of long-term therapy with tricyclic antidepressants in the aged.
Topics: Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Cardiovascular System; | 1979 |
Cardiac responses to imipramine and pancuronium during anesthesia with halothane or enflurane.
Topics: Animals; Arrhythmias, Cardiac; Dogs; Dose-Response Relationship, Drug; Enflurane; Halothane; Heart R | 1979 |
Comparison of the cardiovascular toxicity of three tricyclic antidepressant drugs: imipramine, amitriptyline, and doxepin.
Topics: Amitriptyline; Animals; Arrhythmias, Cardiac; Cardiovascular System; Dogs; Doxepin; Hypotension; Imi | 1979 |
The electrocardiographic and antiarrhythmic effects of imipramine hydrochloride at therapeutic plasma concentrations.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Bundle- | 1979 |
Reversal of neuromuscular blockade and tricyclic antidepressants.
Topics: Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Dogs; Gallamine Triethiodide; Halot | 1979 |
The relative toxicity of amitriptyline, imipramine, maprotiline and mianserin in rabbits in vivo.
Topics: Amitriptyline; Anesthesia; Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Behavior | 1979 |
Tricyclic antidepressants and cardiac conduction: changes in ventricular automaticity.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Blood Pressure; Dogs | 1976 |
Usefulness of physostigmine in imipramine poisoning. A dramatic response in a child resistant to other therapy.
Topics: Arrhythmias, Cardiac; Child, Preschool; Coma; Epilepsy, Tonic-Clonic; Humans; Hypotension; Imipramin | 1976 |
[Poisoning by tricyclic antidepressive agents].
Topics: Arrhythmias, Cardiac; Child; Child, Preschool; Coma; Hallucinations; Humans; Imipramine; Infant | 1977 |
[Arrhythmia and conduction disorders in acute imipramine intoxication].
Topics: Acute Disease; Adolescent; Adult; Arrhythmias, Cardiac; Female; Heart Conduction System; Humans; Imi | 1977 |
Intoxication by tricyclic antidepressant drugs: experimental study and therapeutic considerations.
Topics: Animals; Arrhythmias, Cardiac; Cardiac Output; Dogs; Female; Heart Conduction System; Hemodynamics; | 1977 |
Antidepressant drugs.
Topics: Age Factors; Amitriptyline; Antidepressive Agents; Anxiety; Arrhythmias, Cardiac; Bipolar Disorder; | 1975 |
Electrocardiographic monitoring of enuretic children receiving therapeutic doses of imipramine.
Topics: Arrhythmias, Cardiac; Child; Child, Preschool; Drug Evaluation; Electrocardiography; Enuresis; Femal | 1975 |
Cardiac arrhythmia and imipramine therapy.
Topics: Arrhythmias, Cardiac; Female; Heart Failure; Humans; Imipramine; Middle Aged | 1975 |
Imipramine toxicity.
Topics: Animals; Arrhythmias, Cardiac; Central Nervous System; Coma; Dogs; Dose-Response Relationship, Drug; | 1975 |
Cardiovascular side effects of tricyclic antidepressants - a risk in the use of these drugs.
Topics: Acridines; Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Blood Pressure; Cats; De | 1975 |
[Electrocardiographic changes in acute poisoning by tricyclic drugs].
Topics: Accidents, Home; Adolescent; Arrhythmias, Cardiac; Child, Preschool; Desipramine; Electrocardiograph | 1975 |
Imipramine and 2-hydroxyimipramine: comparative cardiotoxicity and pharmacokinetics in swine.
Topics: Animals; Arrhythmias, Cardiac; Blood Proteins; Cardiac Output; Electrocardiography; Half-Life; Heart | 1992 |
[Anticalcium activity of several antidepressive agents].
Topics: Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Benzamides; | 1992 |
The cardiotoxicity of the tricyclics.
Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Attention Deficit Disorder with Hyperactivit | 1991 |
Suppression of ventricular arrhythmias resulting from acute coronary artery ligation in rat by imipramine.
Topics: Animals; Arrhythmias, Cardiac; Coronary Vessels; Electrocardiography; Imipramine; Male; Procainamide | 1990 |
QRS interval in tricyclic antidepressant overdose.
Topics: Adult; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Desipramine; Electrocardiography; Hea | 1988 |
Comparison of the effect of antidepressant drugs on arrhythmias in the isolated rat heart subjected to myocardial ischaemia and reperfusion.
Topics: Animals; Anti-Arrhythmia Agents; Antidepressive Agents; Arrhythmias, Cardiac; Coronary Disease; Dibe | 1987 |
Cardiovascular effects of polycyclic antidepressants.
Topics: Adult; Amitriptyline; Amoxapine; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Depression; | 1986 |
Effect of fluoxetine on the electrocardiogram.
Topics: Adult; Age Factors; Aged; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Bundle-Branch | 1985 |
Effect of imipramine and nortriptyline on left ventricular function and blood pressure in patients treated for arrhythmias.
Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Drug Administration Schedule; Electrocardiography | 1985 |
Panics, prolapse, and PVCs.
Topics: Adult; Anxiety Disorders; Arrhythmias, Cardiac; Diagnosis, Differential; Fear; Female; Humans; Imipr | 1985 |
Potentially fatal cardiac dysrhythmia and hyperkalemic periodic paralysis.
Topics: Arrhythmias, Cardiac; Biopsy; Child; Electromyography; Humans; Hyperkalemia; Imipramine; Male; Muscl | 1985 |
Treatment of haemodynamic and electrocardiographic side-effects resulting from imipramine toxicity in rats and dogs.
Topics: Animals; Arrhythmias, Cardiac; Chromonar; Coumarins; Dipyridamole; Dogs; Electrocardiography; Female | 1985 |
Adverse reactions to the tricyclic-antidepressant drugs. Report from Boston Collaborative Drug Surveillance Program.
Topics: Amitriptyline; Anxiety; Arrhythmias, Cardiac; Cardiovascular Diseases; Depression; Female; Heart; Hu | 1972 |
Ornade and anticholinergic toxicity: hypertension, hallucinations, and arrhythmias.
Topics: Adolescent; Adult; Arrhythmias, Cardiac; Chlorpheniramine; Clomipramine; Dibenzazepines; Drug Combin | 1974 |
[The effect of imipramine on the cardiac glycoside-induced arrhythmias in animal experiments].
Topics: Animals; Arrhythmias, Cardiac; Citrates; Digoxin; Dogs; Electrocardiography; Female; Heart Conductio | 1968 |
[Abnormal electrocardiographic aspects during experimental acute imipramine poisoning].
Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Bundle-Branch Block; Electrocardiography; Heart; Heart | 1974 |
Cardiotoxic effects of tricyclic antidepressants imipramine, amitriptiline and dosulepin (prothiaden spofa) in an acute experiment in rats.
Topics: Amitriptyline; Animals; Arrhythmias, Cardiac; Dibenzothiepins; Dothiepin; Heart; Imipramine; Rats | 1974 |
The management of imipramine (Tofranil) intoxication in children.
Topics: Adult; Anticonvulsants; Arrhythmias, Cardiac; Electrocardiography; Emergencies; Female; Gastric Lava | 1973 |
ECG monitoring of enuretic children given imipramine.
Topics: Arrhythmias, Cardiac; Child; Child, Preschool; Electrocardiography; Enuresis; Female; Heart; Humans; | 1973 |
The use of sodium bicarbonate in the treatment of tricyclic antidepressant-induced arrhythmias.
Topics: Acid-Base Equilibrium; Acidosis; Amitriptyline; Animals; Antidepressive Agents; Arrhythmias, Cardiac | 1973 |
[Cardiovascular complications of tricyclic anti-depressants. Apropos of a case of acute poisoning].
Topics: Adult; Arrhythmias, Cardiac; Bundle-Branch Block; Diazepam; Digitalis Glycosides; Electrocardiograph | 1973 |
Amitriptyline and imipramine poisoning in children.
Topics: Amitriptyline; Arrhythmias, Cardiac; Child, Preschool; Depression; Enuresis; Female; Humans; Imipram | 1974 |
[Intoxications by tricyclic antidepressants in children].
Topics: Antidepressive Agents; Arrhythmias, Cardiac; Heart Diseases; Humans; Imipramine; Infant; Muscle Cram | 1974 |
The toxicologic and pharmacologic properties of amantadine hydrochloride.
Topics: Abnormalities, Drug-Induced; Acetylcholine; Amantadine; Analgesia; Animals; Arrhythmias, Cardiac; Bl | 1969 |
Electrocardiogram of the month: effects of a psychotropic drug on the electrocardiogram. Imipramine.
Topics: Adult; Arrhythmias, Cardiac; Electrocardiography; Female; Heart; Humans; Imipramine | 1972 |
[Cardiac toxicity of tricyclic antidepressants].
Topics: Adult; Antidepressive Agents; Arrhythmias, Cardiac; Coronary Disease; Electrocardiography; Female; H | 1972 |
Overdosage of tricyclic antidepressants. A report of two deaths and a prospective study of 24 patients.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Bundle-Branch Block; | 1972 |
[Changes in the heart due to phenothiazines and imipramine derivatives].
Topics: Aged; Anticonvulsants; Arrhythmias, Cardiac; Death, Sudden; Electrocardiography; Heart Diseases; Hea | 1971 |
Observations on models used for the evaluation of antiarrhythmic drugs.
Topics: Alkaloids; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutte | 1971 |
Antidepressant overdosage in children--a new menace.
Topics: Accidents, Home; Adolescent; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Child; Chil | 1971 |
ECG changes in fatal imipramine (Tofranil) intoxication.
Topics: Accidents, Home; Arrhythmias, Cardiac; Autopsy; Brain Edema; Electrocardiography; Enuresis; Humans; | 1971 |
[Hemodialysis treatment of a 3 1-4-year-old child with imipramine poisoning].
Topics: Arrhythmias, Cardiac; Charcoal; Child, Preschool; Chloral Hydrate; Electrocardiography; Electroencep | 1970 |
[Antiarrythmic and hemodynamic effects of imipramine and chlorimipramine].
Topics: Alkaloids; Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Dibenzazepines; Dogs; Epin | 1970 |
Antiarrhythmic effects of proadifen hydrochloride (SKF 525-A).
Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Barb | 1970 |
[Treatment of imipramine poisoning at childhood].
Topics: Arrhythmias, Cardiac; Carbon; Child, Preschool; Chloral Hydrate; Coma; Gastric Lavage; Humans; Hypot | 1970 |
[Emergency treatment and transportation of cases of acute imipramine derivative poisoning (apropos of 70 cases)].
Topics: Arrhythmias, Cardiac; Barbiturates; Cardiovascular Diseases; Electrocardiography; First Aid; Humans; | 1970 |
[Cardiotoxicity of tricyclic antidepressive agents. (Phenothiazines and imipramines)].
Topics: Adult; Arrhythmias, Cardiac; Cardiovascular Diseases; Coronary Vessels; Electrocardiography; Epileps | 1971 |
[Cardiac reanimation in poisoning].
Topics: Aconitum; Arrhythmias, Cardiac; Digitalis Glycosides; Heart Arrest; Humans; Imipramine; Quinidine; T | 1967 |
[Cardiac complications in acute poisoning].
Topics: Adolescent; Adult; Amitriptyline; Arrhythmias, Cardiac; Child; Child, Preschool; Chloroquine; Digita | 1967 |
Cardiovascular complications of imipramine intoxication.
Topics: Accidents; Arrhythmias, Cardiac; Cardiac Output; Cardiovascular Diseases; Child, Preschool; Humans; | 1968 |
[Imipramine poisoning and acute cardiac failure. Value of sodium lactate].
Topics: Adult; Arrhythmias, Cardiac; Barbiturates; Chlormethiazole; Electric Countershock; Heart Conduction | 1968 |
Cardiac arrest and arrhythmias due to self-poisoning with imipramine.
Topics: Adult; Antidotes; Arrhythmias, Cardiac; Female; Heart Arrest; Humans; Imipramine; Pyridostigmine Bro | 1969 |
Cardiac abnormalities in poisoning with tricyclic antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents; Arrhythmias, Cardiac; Desipramine; Electrocardiography; | 1969 |
[Effect of toxic doses of imipramine on the isolated heart and ECG in rabbit].
Topics: Animals; Arrhythmias, Cardiac; Electrocardiography; Heart; Heart Rate; Imipramine; In Vitro Techniqu | 1969 |
A possible role of cholinergic effects in the noradrenaline potentiating action of imipramine.
Topics: Animals; Arrhythmias, Cardiac; Bradycardia; Cats; Dogs; Electrocardiography; Female; Hexamethonium C | 1966 |