Page last updated: 2024-10-29

imipramine and Anesthesia

imipramine has been researched along with Anesthesia in 11 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"The incidence of halothane-epinephrine arrhythmias increases after the short-term administration of imipramine, probably because of enhanced noradrenergic transmission."7.67Halothane-epinephrine arrhythmias and adrenergic responsiveness after chronic imipramine administration in dogs. ( Maze, M; Smith, CM; Spiss, CK, 1984)
"The incidence of halothane-epinephrine arrhythmias increases after the short-term administration of imipramine, probably because of enhanced noradrenergic transmission."3.67Halothane-epinephrine arrhythmias and adrenergic responsiveness after chronic imipramine administration in dogs. ( Maze, M; Smith, CM; Spiss, CK, 1984)
" It is concluded that all four drugs show the toxic effects classically associated with tricyclic antidepressants but the relative toxicity amongst these agents varies considerably and is in the order amitriptyline greater than imipramine greater than maprotiline greater than mianserin."1.26The relative toxicity of amitriptyline, imipramine, maprotiline and mianserin in rabbits in vivo. ( Hughes, IE; Radwan, S, 1979)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199011 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MCCANCE, I1
JENKINS, LC1
GRAVES, HB1
Brown, ML1
Gershon, S1
Korol, B1
Spiss, CK1
Smith, CM1
Maze, M1
Byrne, JE1
Gomoll, AW1
Hughes, IE1
Radwan, S1
Lange, SC1
Fowler, GW1
Julien, RM1
Yokota, S1
Ishikura, Y1
Ono, H1
Wood, M1
Suchowsky, GK1
Pegrassi, L1
Tammisto, T1
Ylitalo, P1

Reviews

1 review available for imipramine and Anesthesia

ArticleYear
Plasma drug binding: implications for anesthesiologists.
    Anesthesia and analgesia, 1986, Volume: 65, Issue:7

    Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Ca

1986

Other Studies

10 other studies available for imipramine and Anesthesia

ArticleYear
STUDIES OF POTENTIATION OF HEXOBARBITONE INFUSED INTRAVENOUSLY.
    Archives internationales de pharmacodynamie et de therapie, 1964, Mar-01, Volume: 148

    Topics: Anesthesia; Anesthesia, Intravenous; Anti-Anxiety Agents; Anticonvulsants; Atropine; Benactyzine; Ca

1964
POTENTIAL HAZARDS OF PSYCHOACTIVE DRUGS IN ASSOCIATION WITH ANAESTHESIA.
    Canadian Anaesthetists' Society journal, 1965, Volume: 12

    Topics: Adjuvants, Anesthesia; Amino Alcohols; Amitriptyline; Anesthesia; Antidepressive Agents; Depression;

1965
Some pharmacological effects of a new potential antidepressant cyprolidol (IN-1060) compared with imipramine.
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1966, Volume: 15, Issue:4

    Topics: Acetylcholine; Anesthesia; Animals; Antidepressive Agents; Blood Pressure; Bretylium Compounds; Cats

1966
Halothane-epinephrine arrhythmias and adrenergic responsiveness after chronic imipramine administration in dogs.
    Anesthesia and analgesia, 1984, Volume: 63, Issue:9

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Desipramine; Dogs; Drug Interactions; Epinephrine; Female

1984
Differential effects of trazodone and imipramine on intracardiac conduction in the anesthetized dog.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 259, Issue:2

    Topics: Anesthesia; Animals; Dogs; Electrocardiography; Female; Heart Conduction System; Heart Rate; Imipram

1982
The relative toxicity of amitriptyline, imipramine, maprotiline and mianserin in rabbits in vivo.
    British journal of pharmacology, 1979, Volume: 65, Issue:2

    Topics: Amitriptyline; Anesthesia; Animals; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Behavior

1979
Biphasic action of imipramine in laboratory models of epilepsy.
    Proceedings of the Western Pharmacology Society, 1976, Volume: 19

    Topics: Anesthesia; Animals; Behavior, Animal; Cats; Electroencephalography; Electroshock; Epilepsy; Estroge

1976
Cardiovascular effects of paroxetine, a newly developed antidepressant, in anesthetized dogs in comparison with those of imipramine, amitriptyline and clomipramine.
    Japanese journal of pharmacology, 1987, Volume: 45, Issue:3

    Topics: Amitriptyline; Anesthesia; Animals; Antidepressive Agents; Atrioventricular Node; Blood Pressure; Cl

1987
The pharmacology of 4H-3-methylcarboxyamide-1,3-benzoxazine-2-one (F.I. 6654), a compound acting on the central nervous system.
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:4

    Topics: Anesthesia; Animals; Atropine; Barbiturates; Behavior, Animal; Cats; Central Nervous System; Depress

1969
Tachyphylaxis and toxicity of 5HT in anaesthetized rats.
    Acta pharmacologica et toxicologica, 1969, Volume: 27, Issue:6

    Topics: 5-Hydroxytryptophan; Anesthesia; Animals; Creatinine; Imipramine; Injections, Intravenous; Injection

1969