imipramine has been researched along with Amentia in 33 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the efficacy of paroxetine and imipramine prospectively in patients with coexisting depression and dementia." | 9.08 | A double-blind comparison of the efficacy and safely of paroxetine and imipramine in the treatment of depression with dementia. ( Bray, J; Hunter, BN; Katona, CL, 1998) |
| "To compare the efficacy of paroxetine and imipramine prospectively in patients with coexisting depression and dementia." | 5.08 | A double-blind comparison of the efficacy and safely of paroxetine and imipramine in the treatment of depression with dementia. ( Bray, J; Hunter, BN; Katona, CL, 1998) |
| "Depression is a highly prevalent concomitant of dementia." | 2.40 | Depression and dementia: comorbidities, identification, and treatment. ( Meyers, BS, 1998) |
| "Acute anticholinergic delirium has been reported to occur following ingestion of antidepressants, neuroleptics and antiparkinsonian drugs in toxic and therapeutic doses." | 1.27 | Chronic central anticholinergic toxicity in manic depressive illness mimicking dementia. ( Banno, V; Jones, BD; Moreau, A, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (69.70) | 18.7374 |
| 1990's | 5 (15.15) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (12.12) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Kołaczkowski, M | 4 |
| Marcinkowska, M | 3 |
| Bucki, A | 4 |
| Pawłowski, M | 3 |
| Mitka, K | 1 |
| Jaśkowska, J | 1 |
| Kowalski, P | 1 |
| Kazek, G | 2 |
| Siwek, A | 4 |
| Wasik, A | 2 |
| Wesołowska, A | 4 |
| Mierzejewski, P | 3 |
| Bienkowski, P | 2 |
| Śniecikowska, J | 2 |
| Jastrzębska-Więsek, M | 3 |
| Partyka, A | 3 |
| Więckowski, K | 1 |
| Głuch-Lutwin, M | 2 |
| Gryboś, A | 1 |
| Pytka, K | 1 |
| Zagórska, A | 1 |
| Mordyl, B | 1 |
| Jaromin, A | 1 |
| Walczak, M | 1 |
| Nardi, M | 1 |
| Anwander, M | 1 |
| Rüegger-Frey, B | 1 |
| Bopp-Kistler, I | 1 |
| GRAUER, H | 1 |
| KRAL, VA | 1 |
| ENGELSTOFT, FH | 1 |
| HESHE, J | 1 |
| KIRK, L | 1 |
| LELOUET, JM | 1 |
| BLATRIX, C | 1 |
| JACQUIN, M | 1 |
| SOMMER, A | 1 |
| HAUSNER, M | 1 |
| DOLEZAL, V | 1 |
| LECOMTE, G | 1 |
| ALCALAY, R | 1 |
| MAZZONI, L | 1 |
| DE PALMA, C | 1 |
| Herbert, ME | 1 |
| Jacobson, S | 1 |
| Werner, V | 1 |
| Diehl, LW | 1 |
| Bowen, DM | 1 |
| Allen, SJ | 1 |
| Benton, JS | 1 |
| Goodhardt, MJ | 1 |
| Haan, EA | 1 |
| Palmer, AM | 1 |
| Sims, NR | 1 |
| Smith, CC | 1 |
| Spillane, JA | 1 |
| Esiri, MM | 1 |
| Neary, D | 1 |
| Snowdon, JS | 1 |
| Wilcock, GK | 1 |
| Davison, AN | 1 |
| Mellerup, ET | 1 |
| Plenge, P | 1 |
| Rosenberg, R | 1 |
| Busch, KT | 1 |
| Schulz, H | 1 |
| Klein, DF | 1 |
| Sparks, DL | 2 |
| Danner, FW | 1 |
| Davis, DG | 1 |
| Hackney, C | 1 |
| Landers, T | 1 |
| Coyne, CM | 1 |
| Katona, CL | 1 |
| Hunter, BN | 1 |
| Bray, J | 1 |
| Meyers, BS | 1 |
| Shraberg, D | 1 |
| Husain, MM | 1 |
| Knight, DL | 1 |
| Doraiswamy, PM | 1 |
| Figiel, GS | 1 |
| McDonald, WM | 1 |
| Boyko, OB | 1 |
| Krishnan, KR | 1 |
| Nemeroff, CB | 1 |
| Markesbery, WR | 1 |
| Marcusson, JO | 1 |
| Alafuzoff, I | 1 |
| Bäckström, IT | 1 |
| Ericson, E | 1 |
| Gottfries, CG | 1 |
| Winblad, B | 1 |
| Moreau, A | 1 |
| Jones, BD | 1 |
| Banno, V | 1 |
| Wamboldt, MZ | 1 |
| Kalin, NH | 1 |
| Weiler, SJ | 1 |
| Hall, P | 1 |
| Bertolotti, P | 1 |
| Spaggiari, G | 1 |
| Junod, JP | 1 |
| Webb, WL | 1 |
| Radzuweit, H | 1 |
| Knorr, W | 1 |
| Post, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Controlled, Randomized, Double-Blind Trial of Sertraline in Patients With Frontal Lobe Dementia (FLD)[NCT00001777] | Phase 1 | 30 participants | Interventional | 1997-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for imipramine and Amentia
| Article | Year |
|---|---|
[The state of psychopharmacotherapy in geriatrics 2].
Topics: Actihaemyl; Aged; Amitriptyline; Bencyclane; Cerebrovascular Circulation; Clorazepate Dipotassium; D | 1980 |
Depression and dementia: comorbidities, identification, and treatment.
Topics: Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Benzamides; Citalopram; Clomipramine; Cog | 1998 |
1 trial available for imipramine and Amentia
| Article | Year |
|---|---|
A double-blind comparison of the efficacy and safely of paroxetine and imipramine in the treatment of depression with dementia.
Topics: Aged; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Dementia; Depressi | 1998 |
30 other studies available for imipramine and Amentia
| Article | Year |
|---|---|
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; C | 2014 |
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
Topics: Animals; Benzamides; Dementia; Dose-Response Relationship, Drug; Drug Partial Agonism; Humans; Indol | 2015 |
Novel 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole-Based Multifunctional Ligands with Antipsychotic-Like, Mood-Modulating, and Procognitive Activity.
Topics: Affect; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Dementia; Dopamine Agonist | 2017 |
Design, synthesis, and behavioral evaluation of dual-acting compounds as phosphodiesterase type 10A (PDE10A) inhibitors and serotonin ligands targeting neuropsychiatric symptoms in dementia.
Topics: Animals; Antipsychotic Agents; Dementia; Humans; Ligands; Mice; Phosphoric Diester Hydrolases; Serot | 2022 |
[There's not only Alzheimer's disease].
Topics: Accidental Falls; Aged; Alzheimer Disease; Antidepressive Agents; Cognition Disorders; Comorbidity; | 2012 |
Use of imipramine (Tofranil) in psychiatric patients of a geriatric outpatient clinic.
Topics: Aged; Aged, 80 and over; Aging; Ambulatory Care Facilities; Dementia; Humans; Imipramine; Mental Dis | 1960 |
[Treatment of selected geriatric patients with imipramine (Tofranil)].
Topics: Aged; Aged, 80 and over; Aging; Bipolar Disorder; Dementia; Geriatrics; Imipramine; Mental Disorders | 1962 |
[New indications for tofranil in geriatrics, and especially in diffuse cerebral sclerosis].
Topics: Dementia; Diffuse Cerebral Sclerosis of Schilder; Geriatrics; Humans; Imipramine; Mental Disorders; | 1962 |
[Study of tofranil 10 in gerontological psychiatry].
Topics: Dementia; Geriatrics; Imipramine; Mental Disorders; Psychiatry; Psychotic Disorders | 1962 |
EFFECTS OF IMIPRAMINE UPON VARIOUS MENTAL SYNDROMES IN AMBULATORY TREATMENT.
Topics: Anxiety; Anxiety Disorders; Autonomic Nervous System Diseases; Dementia; Depression; Humans; Imipram | 1963 |
[DISAPPEARANCE OF RECURRENCES IN A PERIODIC SUBJECT (INTERMITTENT MELANCHOLIA) UNDER THE EFFECT OF A CONTINUOUS IMIPRAMINE TREATMENT].
Topics: Dementia; Depressive Disorder; Geriatrics; Humans; Imipramine; Mental Disorders; Periodicity; Psycho | 1963 |
[Contribution to the study of the treatment of depressive forms in senility with a new iminodibenzilic derivative].
Topics: Aging; Dementia; Imipramine; Mental Disorders; Psychotic Disorders | 1961 |
Late paraphrenia.
Topics: Aged; Chlorpromazine; Dementia; Diagnosis, Differential; Electroconvulsive Therapy; Female; Hearing | 1967 |
Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease.
Topics: Acetylcholine; Aged; Alzheimer Disease; Atrophy; Brain; Carrier Proteins; Cerebral Cortex; Dementia; | 1983 |
3H-imipramine binding sites in platelets from psychiatric patients.
Topics: Antidepressive Agents; Binding, Competitive; Bipolar Disorder; Blood Platelets; Carrier Proteins; De | 1982 |
[The acute psychiatric emergency].
Topics: Acute Disease; Aged; Alcoholism; Amitriptyline; Brain Ischemia; Cognition Disorders; Consciousness D | 1981 |
Clinical and biological aspects of depression in the elderly.
Topics: Aged; Dementia; Depression; Doxepin; Humans; Imipramine; Methylphenidate; Middle Aged; Trazodone | 1980 |
Neurochemical and histopathologic alterations characteristic of Pick's disease in a non-demented individual.
Topics: Acetylcholinesterase; Aged; Brain; Carrier Proteins; Choline O-Acetyltransferase; Cognition; Coronar | 1994 |
The myth of pseudodementia: depression and the aging brain.
Topics: Aged; Dementia; Depression; Diagnosis, Differential; Humans; Imipramine; Male | 1978 |
Platelet [3H]-imipramine binding and leukoencephalopathy in geriatric depression.
Topics: Aged; Aged, 80 and over; Blood Platelets; Brain; Carrier Proteins; Dementia; Depressive Disorder; Fe | 1991 |
Altered serotonergic and cholinergic synaptic markers in Pick's disease.
Topics: Acetylcholinesterase; Aged; Brain; Choline O-Acetyltransferase; Dementia; Female; Frontal Lobe; Huma | 1991 |
5-Hydroxytryptamine-sensitive [3H]imipramine binding of protein nature in the human brain. II. Effect of normal aging and dementia disorders.
Topics: Aged; Aging; Alzheimer Disease; Brain; Dementia; Humans; Imipramine; Middle Aged; Nerve Tissue Prote | 1987 |
Chronic central anticholinergic toxicity in manic depressive illness mimicking dementia.
Topics: Aged; Amitriptyline; Benztropine; Bipolar Disorder; Central Nervous System Diseases; Dementia; Diagn | 1986 |
Consistent reversal of abnormal DSTs after different antidepressant therapies in a patient with dementia.
Topics: Amitriptyline; Antidepressive Agents; Dementia; Depressive Disorder; Dexamethasone; Humans; Hydrocor | 1985 |
Differential diagnosis and treatment of depression in the elderly.
Topics: Adjustment Disorders; Aged; Antidepressive Agents; Circadian Rhythm; Dementia; Depression; Diagnosis | 1974 |
[Note on the use of dihydrogenated derivatives of ergotoxin (Hydergine) and their association with psychopharmacology in the treatment of aged neuropsychiatric patients].
Topics: Aged; Barbiturates; Butyrophenones; Dementia; Ergoloid Mesylates; Female; Humans; Imipramine; Male; | 1966 |
[The use of psychotropic drugs in geriatrics].
Topics: Aged; Antidepressive Agents; Behavior; Dementia; Depression; Humans; Imipramine; Mental Disorders; T | 1972 |
The use of psychopharmacological drugs in the aged.
Topics: Affective Symptoms; Aged; Antidepressive Agents; Anxiety; Barbiturates; Butyrophenones; Dementia; De | 1971 |
[Influencing of biological and immunologic pregnancy reactions by psychotropic drugs].
Topics: Adolescent; Adult; Aged; Butyrophenones; Chlorpromazine; Dementia; Depressive Disorder, Major; Dysau | 1969 |
Management of senile psychiatric disorders.
Topics: Adjustment Disorders; Affective Symptoms; Aged; Alcoholism; Amitriptyline; Dementia; Depressive Diso | 1968 |