Page last updated: 2024-10-29

imipramine and Alcohol Drinking

imipramine has been researched along with Alcohol Drinking in 7 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.

Research Excerpts

ExcerptRelevanceReference
"Of 60 depressed alcoholics who completed an open trial of imipramine, 27 (45%) responded with improvement in both mood and drinking behavior, and eight (13%) responded after further dosage increases or treatment with disulfiram."6.67Imipramine treatment of alcoholism with comorbid depression. ( Harrison, W; McGrath, PJ; Nunes, EV; Ocepek-Welikson, K; Quitkin, FM; Stewart, JP; Tricamo, E, 1993)
"Imipramine treatment was safe and associated with improvement in depression in both adequately treated and intention-to-treat samples."2.68Imipramine treatment of alcoholics with primary depression: A placebo-controlled clinical trial. ( Agosti, V; Goldman, D; McGrath, PJ; Nunes, EV; Ocepek-Welikson, K; Quitkin, FM; Stewart, JW, 1996)
"Of 60 depressed alcoholics who completed an open trial of imipramine, 27 (45%) responded with improvement in both mood and drinking behavior, and eight (13%) responded after further dosage increases or treatment with disulfiram."2.67Imipramine treatment of alcoholism with comorbid depression. ( Harrison, W; McGrath, PJ; Nunes, EV; Ocepek-Welikson, K; Quitkin, FM; Stewart, JP; Tricamo, E, 1993)
"Patients with major depressive disorder (MDD) frequently also have alcohol use disorder (AUD) and they are more likely to experience symptomatic recurrence and resist treatment."1.42Influence of comorbid alcohol use disorder on treatment response of depressive patients. ( Hashimoto, E; Ishikawa, H; Saito, T; Tayama, M; Yamamoto, M, 2015)
"Three mothers of infants with holoprosencephaly consumed alcohol heavily in pregnancy."1.28Holoprosencephaly as a possible embryonic alcohol effect. ( Andrews, WL; Ronen, GM, 1991)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's4 (57.14)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hashimoto, E1
Tayama, M1
Ishikawa, H1
Yamamoto, M1
Saito, T1
Katkov, YA1
Otmakhova, NA1
Gurevich, EV1
Nesterova, IV1
Bobkova, NV1
Nunes, EV2
McGrath, PJ2
Quitkin, FM2
Stewart, JP1
Harrison, W1
Tricamo, E1
Ocepek-Welikson, K2
Stewart, JW1
Goldman, D1
Agosti, V1
Zafar, H1
Shelat, SG1
Redei, E1
Tejani-Butt, S1
Ronen, GM1
Andrews, WL1
Milner, G1

Trials

2 trials available for imipramine and Alcohol Drinking

ArticleYear
Imipramine treatment of alcoholism with comorbid depression.
    The American journal of psychiatry, 1993, Volume: 150, Issue:6

    Topics: Adult; Affect; Alcohol Drinking; Alcoholism; Comorbidity; Depressive Disorder; Disulfiram; Dose-Resp

1993
Imipramine treatment of alcoholics with primary depression: A placebo-controlled clinical trial.
    Archives of general psychiatry, 1996, Volume: 53, Issue:3

    Topics: Adult; Alcohol Drinking; Alcoholics Anonymous; Alcoholism; Ambulatory Care; Depressive Disorder; Fem

1996

Other Studies

5 other studies available for imipramine and Alcohol Drinking

ArticleYear
Influence of comorbid alcohol use disorder on treatment response of depressive patients.
    Journal of neural transmission (Vienna, Austria : 1996), 2015, Volume: 122, Issue:2

    Topics: Adult; Alcohol Drinking; Alcoholism; Antidepressive Agents; Depressive Disorder, Major; Female; Foll

2015
Antidepressants suppress bulbectomy-induced augmentation of voluntary alcohol consumption in C57B1/6j but not in DBA/2j mice.
    Physiology & behavior, 1994, Volume: 56, Issue:3

    Topics: Alcohol Drinking; Amitriptyline; Animals; Antidepressive Agents; Arousal; Depressive Disorder; Disea

1994
Fetal alcohol exposure alters serotonin transporter sites in rat brain.
    Brain research, 2000, Feb-21, Volume: 856, Issue:1-2

    Topics: Alcohol Drinking; Analysis of Variance; Animals; Autoradiography; Brain; Carrier Proteins; Female; F

2000
Holoprosencephaly as a possible embryonic alcohol effect.
    American journal of medical genetics, 1991, Aug-01, Volume: 40, Issue:2

    Topics: Abnormalities, Drug-Induced; Alcohol Drinking; Chlordiazepoxide; Female; Holoprosencephaly; Humans;

1991
Drinking and driving in 753 general practice and psychiatric patients on psychotropic drugs.
    The British journal of psychiatry : the journal of mental science, 1969, Volume: 115, Issue:518

    Topics: Alcohol Drinking; Amitriptyline; Automobile Driving; Barbiturates; Chlordiazepoxide; Diazepam; Drug

1969