imipramine has been researched along with Age-Related Memory Disorders in 16 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sweroside is a secoiridoid glycoside and belongs to a large group of naturally occurring monoterpenes with glucose sugar attached to C-1 in the pyran ring." | 1.72 | Sweroside Ameliorated Memory Deficits in Scopolamine-Induced Zebrafish ( ( Brinza, I; El-Kashak, W; Eldahshan, OA; Hritcu, L; Raey, MAE, 2022) |
| "Imipramine is a kind of tricyclic antidepressant with reported anti-inflammatory and anti-oxidant effects in the brain." | 1.62 | Imipramine alleviates memory impairment and hippocampal apoptosis in STZ-induced sporadic Alzheimer's rat model: Possible contribution of MAPKs and insulin signaling. ( Ahmadiani, A; Askari, S; Dargahi, L; Ghasemi, R; Javadpour, P; Rashidi, FS, 2021) |
| "Imipramine has been widely used as an antidepressant in the clinic over the years." | 1.56 | NS398, a cyclooxygenase-2 inhibitor, reverses memory performance disrupted by imipramine in C57Bl/6J mice. ( Bobula, B; Stachowicz, K; Tokarski, K, 2020) |
| "Imipramine significantly prevented memory deficits caused by Abeta25-35 in the water-maze and Y-maze tests, and inhibited the TNF-alpha increase in the frontal cortex." | 1.36 | Imipramine, in part through tumor necrosis factor alpha inhibition, prevents cognitive decline and beta-amyloid accumulation in a mouse model of Alzheimer's disease. ( Chavant, F; Deguil, J; Fauconneau, B; Ingrand, I; Lafay-Chebassier, C; Milin, S; Pain, S; Pérault-Pochat, MC, 2010) |
| "The results showed that memory deficits were reversed with curcumin in a dose dependent manner, as were stress-induced increases in serum corticosterone levels." | 1.35 | Curcumin reverses impaired cognition and neuronal plasticity induced by chronic stress. ( Barish, PA; Li, G; Li, S; Lin, D; Ogle, WO; Pan, J; Shyamala, SG; Vernon, MM; Xu, Y, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Sang, Z | 2 |
| Pan, W | 1 |
| Wang, K | 2 |
| Ma, Q | 1 |
| Yu, L | 1 |
| Yang, Y | 1 |
| Bai, P | 2 |
| Leng, C | 1 |
| Xu, Q | 1 |
| Li, X | 1 |
| Tan, Z | 1 |
| Liu, W | 1 |
| Zhang, P | 1 |
| Shi, J | 1 |
| Cheng, X | 1 |
| Zhang, Q | 1 |
| Zheng, C | 1 |
| Cheng, Y | 1 |
| Yang, J | 1 |
| Lu, X | 1 |
| Brinza, I | 1 |
| Raey, MAE | 1 |
| El-Kashak, W | 1 |
| Eldahshan, OA | 1 |
| Hritcu, L | 1 |
| Stachowicz, K | 1 |
| Bobula, B | 1 |
| Tokarski, K | 1 |
| Javadpour, P | 1 |
| Askari, S | 1 |
| Rashidi, FS | 1 |
| Dargahi, L | 1 |
| Ahmadiani, A | 1 |
| Ghasemi, R | 1 |
| de Rezende, VB | 1 |
| Rosa, DV | 1 |
| Comim, CM | 1 |
| Magno, LA | 1 |
| Rodrigues, AL | 1 |
| Vidigal, P | 1 |
| Jeromin, A | 1 |
| Quevedo, J | 1 |
| Romano-Silva, MA | 1 |
| Marszalek-Grabska, M | 1 |
| Gibula-Bruzda, E | 1 |
| Jenda, M | 1 |
| Gawel, K | 1 |
| Kotlinska, JH | 1 |
| Xu, Y | 1 |
| Lin, D | 1 |
| Li, S | 1 |
| Li, G | 1 |
| Shyamala, SG | 1 |
| Barish, PA | 1 |
| Vernon, MM | 1 |
| Pan, J | 1 |
| Ogle, WO | 1 |
| Chavant, F | 1 |
| Deguil, J | 1 |
| Pain, S | 1 |
| Ingrand, I | 1 |
| Milin, S | 1 |
| Fauconneau, B | 1 |
| Pérault-Pochat, MC | 1 |
| Lafay-Chebassier, C | 1 |
| Cline, BH | 1 |
| Steinbusch, HW | 1 |
| Malin, D | 1 |
| Revishchin, AV | 1 |
| Pavlova, GV | 1 |
| Cespuglio, R | 1 |
| Strekalova, T | 1 |
| Garcia-Toro, M | 1 |
| Talavera, JA | 1 |
| Gonzalez, E | 1 |
| Tejada, P | 1 |
| Blanco, C | 1 |
| Gonzalez, A | 1 |
| Saiz-Ruiz, J | 1 |
| Zarrindast, MR | 1 |
| Shamsi, T | 1 |
| Azarmina, P | 1 |
| Rostami, P | 1 |
| Shafaghi, B | 1 |
| Crowe, RR | 1 |
| Glass, RM | 1 |
| Uhlenhuth, EH | 1 |
| Hartel, FW | 1 |
| Matuzas, W | 1 |
| Fischman, MW | 1 |
| Sternberg, DE | 1 |
| Jarvik, ME | 1 |
| Jenkins, RB | 1 |
| Groh, RH | 1 |
1 review available for imipramine and Age-Related Memory Disorders
| Article | Year |
|---|---|
Current concepts. Electroconvulsive therapy--a current perspective.
Topics: Depression; Electroconvulsive Therapy; Humans; Imipramine; Memory Disorders; Methods; Patient Accept | 1984 |
1 trial available for imipramine and Age-Related Memory Disorders
| Article | Year |
|---|---|
Cognitive dysfunction and imipramine in outpatient depressive.
Topics: Adult; Attention; Clinical Trials as Topic; Cognition Disorders; Depressive Disorder; Double-Blind M | 1981 |
14 other studies available for imipramine and Age-Related Memory Disorders
| Article | Year |
|---|---|
Design, synthesis and evaluation of novel ferulic acid-O-alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Butyrylcholine | 2017 |
Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Biological Tr | 2019 |
Sweroside Ameliorated Memory Deficits in Scopolamine-Induced Zebrafish (
Topics: Acetylcholinesterase; Animals; Anti-Bacterial Agents; Antifungal Agents; Antioxidants; Brain; Cholin | 2022 |
NS398, a cyclooxygenase-2 inhibitor, reverses memory performance disrupted by imipramine in C57Bl/6J mice.
Topics: Animals; Antidepressive Agents, Tricyclic; Brain; Cyclooxygenase 2 Inhibitors; Imipramine; Maze Lear | 2020 |
Imipramine alleviates memory impairment and hippocampal apoptosis in STZ-induced sporadic Alzheimer's rat model: Possible contribution of MAPKs and insulin signaling.
Topics: Adrenergic Uptake Inhibitors; Alzheimer Disease; Animals; Antibiotics, Antineoplastic; Behavior, Ani | 2021 |
NCS-1 deficiency causes anxiety and depressive-like behavior with impaired non-aversive memory in mice.
Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety Disorders; Avoidance Learnin | 2014 |
Memantine improves memory impairment and depressive-like behavior induced by amphetamine withdrawal in rats.
Topics: Amphetamine; Amphetamine-Related Disorders; Animals; Antidepressive Agents; Central Nervous System S | 2016 |
Curcumin reverses impaired cognition and neuronal plasticity induced by chronic stress.
Topics: Animals; Antidepressive Agents, Tricyclic; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells | 2009 |
Imipramine, in part through tumor necrosis factor alpha inhibition, prevents cognitive decline and beta-amyloid accumulation in a mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cognition; Diseas | 2010 |
The neuronal insulin sensitizer dicholine succinate reduces stress-induced depressive traits and memory deficit: possible role of insulin-like growth factor 2.
Topics: Animals; Antidepressive Agents; Anxiety; Depression; Disease Models, Animal; Hippocampus; Imipramine | 2012 |
Audioverbal cognitive dysfunction in depression. Factors involved.
Topics: Adolescent; Adult; Antidepressive Agents; Antidepressive Agents, Tricyclic; Attention; Cognition Dis | 2003 |
GABAergic system and imipramine-induced impairment of memory retention in rats.
Topics: Animals; Avoidance Learning; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA | 2004 |
Memory functions in depression.
Topics: Amitriptyline; Depression; Female; Humans; Imipramine; Male; Memory Disorders; Memory, Short-Term | 1976 |
Mental symptoms in Parkinsonian patients treated with L-dopa.
Topics: Aged; Behavior; Depression; Dihydroxyphenylalanine; Dreams; Female; Humans; Imipramine; Male; Memory | 1970 |