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imipramine and Affective Disorders, Psychotic

imipramine has been researched along with Affective Disorders, Psychotic in 27 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Affective Disorders, Psychotic: Disorders in which the essential feature is a severe disturbance in mood (depression, anxiety, elation, and excitement) accompanied by psychotic symptoms such as delusions, hallucinations, gross impairment in reality testing, etc.

Research Excerpts

ExcerptRelevanceReference
"The authors reevaluate a large prospective Italian study (437 patients) that compared high-dose imipramine with ECT treatment in the treatment of depression."7.66Depression treated with imipramine and ECT: the DeCarolis study reconsidered. ( Avery, D; Lubrano, A, 1979)
"The introduction of two tricyclic compounds (iprindole and mianserin) that are reported to have antidepressant properties but to be relatively devoid of effects on central amine neurotransmitter systems has raised questions about the amine hypothesis of depression and about the mechanism of action of tricyclics in general."7.66Novel antidepressants and the biogenic amine hypothesis of depression. The case for iprindole and mianserin. ( Goodwin, FK; Zis, AP, 1979)
"The authors reevaluate a large prospective Italian study (437 patients) that compared high-dose imipramine with ECT treatment in the treatment of depression."3.66Depression treated with imipramine and ECT: the DeCarolis study reconsidered. ( Avery, D; Lubrano, A, 1979)
"The introduction of two tricyclic compounds (iprindole and mianserin) that are reported to have antidepressant properties but to be relatively devoid of effects on central amine neurotransmitter systems has raised questions about the amine hypothesis of depression and about the mechanism of action of tricyclics in general."3.66Novel antidepressants and the biogenic amine hypothesis of depression. The case for iprindole and mianserin. ( Goodwin, FK; Zis, AP, 1979)
"Imipramine doses were adjusted to attain a predefined fixed plasma level."1.35Efficacy of imipramine in psychotic versus nonpsychotic depression. ( Birkenhager, TK; Bruijn, JA; Moleman, P; Mulder, PG; van den Broek, WW, 2008)
"Thirty-six patients with major depressive disorder diagnosed according to DSM-IV, and 20 healthy control subjects were involved in the study."1.32P300 changes in major depressive disorders with and without psychotic features. ( Erdinc, E; Esel, E; Gonul, AS; Karaaslan, F; Oguz, A, 2003)
" Chronic administration of lithium was found to prevent the development of hyperreactivity to mild footshock, while chronic electroconvulsive shock effected a return toward normal behavior."1.26A pharmacologically pertinent animal model of mania. ( Petty, F; Sherman, AD, 1981)
" The achievement of such results with moderate doses might indicate a possible relationship between the optimal dosage of the antidepressive drug and the intensity of the mood disorder."1.26[Imipramine and neuro-psychiatry. Retrospective study of 557 out-patients treated in a neuro-psychiatric unit (author's transl)]. ( Boulenger, JP; Brion, S, 1982)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199021 (77.78)18.7374
1990's1 (3.70)18.2507
2000's3 (11.11)29.6817
2010's2 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baldessarini, RJ1
Wijkstra, J2
Burger, H2
van den Broek, WW3
Birkenhäger, TK3
Janzing, JG2
Boks, MP2
Bruijn, JA3
van der Loos, ML2
Breteler, LM2
Ramaekers, GM1
Verkes, RJ2
Nolen, WA2
Karaaslan, F1
Gonul, AS1
Oguz, A1
Erdinc, E1
Esel, E1
Mulder, PG1
Moleman, P1
Muscettola, G1
Di Lauro, A1
Giannini, CP1
Petty, F1
Sherman, AD1
Cashman, FE1
Pollock, B1
Brown, RP1
Sweeney, J1
Frances, A1
Kocsis, JH2
Loutsch, E1
Linnoila, M1
Gold, P1
Potter, WZ1
Wehr, TA1
Jann, MW1
Bitar, AH1
Rao, A1
Nasrallah, HA1
Lyskowksi, J1
Schroeder, D1
Brion, S1
Boulenger, JP1
Welner, A1
Welner, Z1
Robins, E1
de la Fuente, JR1
Rosenbaum, AH1
Steele, TE1
Taylor, CI1
Mirin, SM1
Schatzberg, AF1
Creasey, DE1
Keller, MB1
Harrison, W1
Fawcett, JA1
Gelenberg, A1
Hirschfeld, RM1
Klein, D1
McCullough, JP1
Rush, AJ1
Schatzberg, A1
Davidson, JR1
McLeod, MN1
Kurland, AA1
White, HL1
Perry, GF1
Fitzsimmons, B1
Shapiro, L1
Irwin, P1
Pichot, P1
Dreyfus, JF1
Pull, C1
Raskin, A1
Boothe, H1
Reatig, N1
Schulterbrandt, JG1
Avery, D1
Lubrano, A1
Zis, AP1
Goodwin, FK1
Egan, WH1
Smith, JA1
Cutler, NR1
Anderson, DJ1
Siris, SG1
Sellew, AP1
Frechen, K1
Cooper, TB1
Mandell, J1
Casey, E1

Reviews

1 review available for imipramine and Affective Disorders, Psychotic

ArticleYear
Blood cells as biological trait markers in affective disorders.
    Journal of psychiatric research, 1984, Volume: 18, Issue:4

    Topics: Affective Disorders, Psychotic; Anorexia Nervosa; Blood Platelets; Erythrocytes; Female; Humans; Imi

1984

Trials

9 trials available for imipramine and Affective Disorders, Psychotic

ArticleYear
Treatment of unipolar psychotic depression: a randomized, double-blind study comparing imipramine, venlafaxine, and venlafaxine plus quetiapine.
    Acta psychiatrica Scandinavica, 2010, Volume: 121, Issue:3

    Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Antidepressive Agents, Tricyclic; Antipsych

2010
Long-term response to successful acute pharmacological treatment of psychotic depression.
    Journal of affective disorders, 2010, Volume: 123, Issue:1-3

    Topics: Adult; Affective Disorders, Psychotic; Antidepressive Agents; Antipsychotic Agents; Cyclohexanols; D

2010
Effect of tricyclic antidepressants on individual symptoms.
    The Journal of clinical psychiatry, 1980, Volume: 41, Issue:9

    Topics: Affective Disorders, Psychotic; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder

1980
Treatment of chronic depression with sertraline or imipramine: preliminary blinded response rates and high rates of undertreatment in the community.
    Psychopharmacology bulletin, 1995, Volume: 31, Issue:2

    Topics: 1-Naphthylamine; Adult; Affective Disorders, Psychotic; Aged; Chronic Disease; Depression; Female; F

1995
Antidepressant drug therapy in psychotic depression.
    The British journal of psychiatry : the journal of mental science, 1977, Volume: 131

    Topics: Adult; Affective Disorders, Psychotic; Clinical Trials as Topic; Delusions; Desipramine; Double-Blin

1977
Clinical study of mianserin, imipramine and placebo in depression: blood level and MHPG correlations.
    British journal of clinical pharmacology, 1978, Volume: 5 Suppl 1

    Topics: Adjustment Disorders; Adolescent; Adult; Affective Disorders, Psychotic; Aged; Clinical Trials as To

1978
A double-blind multicentre trial comparing mianserin with imipramine.
    British journal of clinical pharmacology, 1978, Volume: 5 Suppl 1

    Topics: Adjustment Disorders; Adolescent; Adult; Affective Disorders, Psychotic; Aged; Clinical Trials as To

1978
Initial response to drugs in depressive illness and psychiatric and community adjustment a year later.
    Psychological medicine, 1978, Volume: 8, Issue:1

    Topics: Adjustment Disorders; Adult; Affective Disorders, Psychotic; Chlorpromazine; Clinical Trials as Topi

1978
Antidepressants in the treatment of post-psychotic depression in schizophrenia: drug interactions and other considerations.
    Clinical chemistry, 1988, Volume: 34, Issue:5

    Topics: Adult; Affective Disorders, Psychotic; Benztropine; Clinical Trials as Topic; Drug Interactions; Flu

1988

Other Studies

17 other studies available for imipramine and Affective Disorders, Psychotic

ArticleYear
Comments on article by Dr Birkenhager et al: "Efficacy of imipramine in psychotic versus nonpsychotic depression".
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:6

    Topics: Adrenergic Uptake Inhibitors; Affective Disorders, Psychotic; Antidepressive Agents, Tricyclic; Depr

2008
P300 changes in major depressive disorders with and without psychotic features.
    Journal of affective disorders, 2003, Volume: 73, Issue:3

    Topics: Adult; Affective Disorders, Psychotic; Antidepressive Agents; Antipsychotic Agents; Cerebral Cortex;

2003
Efficacy of imipramine in psychotic versus nonpsychotic depression.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:2

    Topics: Adult; Affective Disorders, Psychotic; Aged; Antidepressive Agents; Data Interpretation, Statistical

2008
A pharmacologically pertinent animal model of mania.
    Journal of affective disorders, 1981, Volume: 3, Issue:4

    Topics: Affective Disorders, Psychotic; Animals; Bipolar Disorder; Disease Models, Animal; Electroshock; Hum

1981
Treatment of monosymptomatic hypochondriacal psychosis with imipramine.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1983, Volume: 28, Issue:1

    Topics: Adult; Affective Disorders, Psychotic; Delusions; Humans; Hypochondriasis; Imipramine; Male

1983
Age as a predictor of treatment response in endogenous depression.
    Journal of clinical psychopharmacology, 1983, Volume: 3, Issue:3

    Topics: Adult; Affective Disorders, Psychotic; Age Factors; Aged; Amitriptyline; Antidepressive Agents, Tric

1983
Tricyclic antidepressants do not alter thyroid hormone levels in patients suffering from a major affective disorder.
    Psychiatry research, 1981, Volume: 4, Issue:3

    Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Amitriptyline; Antidepressive Agents, Tricy

1981
Lithium prophylaxis of tricyclic-antidepressant-induced mania in bipolar patients.
    The American journal of psychiatry, 1982, Volume: 139, Issue:5

    Topics: Adult; Affective Disorders, Psychotic; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Diso

1982
TCA-induced mania: differences between switchers and nonswitchers.
    Biological psychiatry, 1982, Volume: 17, Issue:2

    Topics: Adult; Affective Disorders, Psychotic; Age Factors; Amitriptyline; Antidepressive Agents, Tricyclic;

1982
[Imipramine and neuro-psychiatry. Retrospective study of 557 out-patients treated in a neuro-psychiatric unit (author's transl)].
    L'Encephale, 1982, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Affective Disorders, Psychotic; Aged; Bipolar Disorder; Depressive Disorder; Depr

1982
Neuroendocrine dysfunction and blood levels of tricyclic antidepressants.
    The American journal of psychiatry, 1980, Volume: 137, Issue:10

    Topics: Adolescent; Adrenal Cortex Hormones; Affective Disorders, Psychotic; Dexamethasone; Diagnosis, Diffe

1980
Hypomania and tricyclic antidepressant choice.
    The American journal of psychiatry, 1980, Volume: 137, Issue:11

    Topics: Adult; Affective Disorders, Psychotic; Aged; Amitriptyline; Bipolar Disorder; Depressive Disorder; F

1980
Hypomania and mania after withdrawal of tricyclic antidepressants.
    The American journal of psychiatry, 1981, Volume: 138, Issue:1

    Topics: Adult; Affective Disorders, Psychotic; Amitriptyline; Antidepressive Agents, Tricyclic; Bipolar Diso

1981
Depression treated with imipramine and ECT: the DeCarolis study reconsidered.
    The American journal of psychiatry, 1979, Volume: 136, Issue:4B

    Topics: Adjustment Disorders; Affective Disorders, Psychotic; Bipolar Disorder; Delusions; Depression; Dose-

1979
Novel antidepressants and the biogenic amine hypothesis of depression. The case for iprindole and mianserin.
    Archives of general psychiatry, 1979, Volume: 36, Issue:10

    Topics: Adjustment Disorders; Affective Disorders, Psychotic; Amitriptyline; Biogenic Amines; Brain; Depress

1979
The unremembered, unimproved depressed patient.
    American family physician, 1977, Volume: 15, Issue:4

    Topics: Adjustment Disorders; Affective Disorders, Psychotic; Amitriptyline; Depression; Electroshock; Human

1977
Proven asymptomatic eosinophilia with imipramine.
    The American journal of psychiatry, 1977, Volume: 134, Issue:11

    Topics: Affective Disorders, Psychotic; Dose-Response Relationship, Drug; Eosinophilia; Humans; Imipramine;

1977