Compounds > imipramine
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imipramine and Abnormalities, Drug-Induced

imipramine has been researched along with Abnormalities, Drug-Induced in 38 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
"Three mothers of infants with holoprosencephaly consumed alcohol heavily in pregnancy."1.28Holoprosencephaly as a possible embryonic alcohol effect. ( Andrews, WL; Ronen, GM, 1991)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199036 (94.74)18.7374
1990's2 (5.26)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ROBSON, JM1
WORTIS, J1
LARSEN, V1
Tuchmann-Duplessis, H1
Benesová, O1
Rumeau-Rouquette, C1
Goujard, J1
Huel, G1
Fickentscher, K1
Köhler, F1
Rise, A1
Bílá, V1
Kren, V1
Ronen, GM1
Andrews, WL1
Idänpään-Heikkilä, J1
Saxén, L1
Klaukka, T1
Sim, M1
Nelson, SR1
Walaszek, EJ1
Morrow, AW3
Chambiras, PG1
Shapiro, IuL1
Vaĭntrub, MIa1
Grinberg, KN1
Zhurkov, VS1
Wilson, JG1
Rowe, IL1
Gilani, SH1
Vernier, VG1
Harmon, JB1
Stump, JM1
Lynes, TE1
Marvel, JP1
Smith, DH1
Crombie, DL1
Pinsent, RJ1
Fleming, D1
Barson, AJ1
Kuenssberg, EV1
Knox, JD1
McBride, WG1
Brown, R1
Swan, E2
Hughes, WW1
Jacobs, D1
Minde, M1
Rockey, T1
Pitt, DB1
Wilkins, GD1
Levy, L1
Aeppli, L1

Reviews

7 reviews available for imipramine and Abnormalities, Drug-Induced

ArticleYear
THE PROBLEM OF TERATOGENICITY.
    The Practitioner, 1963, Volume: 191

    Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Cyclizine; Female; Imipramine; Nicotine; Preg

1963
PSYCHOPHARMACOLOGY AND PHYSIOLOGICAL TREATMENT.
    The American journal of psychiatry, 1964, Volume: 120

    Topics: Abnormalities, Drug-Induced; Cheese; Imipramine; Psychopharmacology; Toxicology; Tranylcypromine; Ty

1964
The teratogenic risk.
    American journal of industrial medicine, 1983, Volume: 4, Issue:1-2

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Amphetamine; Animals; Anticoagulants; Anticonv

1983
[Are nervous system drugs teratogenic? Evaluation of epidemiologic studies].
    Archives francaises de pediatrie, 1976, Volume: 33, Issue:1

    Topics: Abnormalities, Drug-Induced; Amphetamines; Anticonvulsants; Antipsychotic Agents; Female; Humans; Im

1976
Pharmacology of the central nervous system.
    Progress in neurology and psychiatry, 1968, Volume: 23

    Topics: Abnormalities, Drug-Induced; Acetylcholine; Adrenocorticotropic Hormone; Amphetamine; Anger; Angiote

1968
[Teratogenic and mutagenic effects of anticonvulsive and psychotropic drugs (review of the literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:6

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Antidepressive Agent

1972
Present status of drugs as teratogens in man.
    Teratology, 1973, Volume: 7, Issue:1

    Topics: Abnormalities, Drug-Induced; Alkylating Agents; Anti-Bacterial Agents; Anticonvulsants; Antiemetics;

1973

Other Studies

31 other studies available for imipramine and Abnormalities, Drug-Induced

ArticleYear
THE TERATOGENIC EFFECTS OF THALIDOMIDE, IMIPRAMINE HC1 AND IMIPRAMINE-N-OXIDE HC1 ON WHITE DANISH RABBITS.
    Acta pharmacologica et toxicologica, 1963, Volume: 20

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Female; Fetal Diseases; Humans; Imipramine;

1963
To the pharmacological profile of maprotiline.
    Activitas nervosa superior, 1982, Volume: 24, Issue:2

    Topics: Abnormalities, Drug-Induced; Adult; Animals; Anthracenes; Arousal; Chick Embryo; Depressive Disorder

1982
Teratogenicity and embryotoxicity of some maleinimides.
    Archives of toxicology, 1976, Dec-23, Volume: 37, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Imides; Imipramine; Maleimides; Mice; Pht

1976
[Antidepressive agents].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Feb-28, Volume: 96, Issue:6

    Topics: Abnormalities, Drug-Induced; Antidepressive Agents; Female; Humans; Imipramine; Infant, Newborn; Mat

1976
Teratogenicity testing based on the interaction with a mutant allele.
    Folia biologica, 1992, Volume: 38, Issue:1

    Topics: Abnormalities, Drug-Induced; Alleles; Animals; Anti-Bacterial Agents; Cyclophosphamide; Female; Fetu

1992
Holoprosencephaly as a possible embryonic alcohol effect.
    American journal of medical genetics, 1991, Aug-01, Volume: 40, Issue:2

    Topics: Abnormalities, Drug-Induced; Alcohol Drinking; Chlordiazepoxide; Female; Holoprosencephaly; Humans;

1991
Rachelefsky GS, Flynt JW Jr,+FLYNT JW JR, Ebbin AJ, Wilson MG, Banister P, Dafoe C, Smith ES, Miller J:Possible teratogenicity of tricyclic antidepressants.
    Lancet (London, England), 1972, Apr-15, Volume: 1, Issue:7755

    Topics: Abnormalities, Drug-Induced; Amitriptyline; Antidepressive Agents; Female; Humans; Imipramine; Infan

1972
Possible teratogenicity of imipramine-chloropyramine.
    Lancet (London, England), 1973, Aug-11, Volume: 2, Issue:7824

    Topics: Abnormalities, Drug-Induced; Adult; Amitriptyline; Antidepressive Agents; Benzyl Compounds; Drug Com

1973
[Can imipramine-chlorpyramine be teratogenic?].
    Katilolehti, 1973, Volume: 78, Issue:11

    Topics: Abnormalities, Drug-Induced; Histamine H1 Antagonists; Imipramine; Pyridines

1973
Imipramine and pregnancy.
    British medical journal, 1972, Apr-01, Volume: 2, Issue:5804

    Topics: Abnormalities, Drug-Induced; Depression; Down Syndrome; Female; Fetal Death; Humans; Imipramine; Pre

1972
Imipramine and congenital abnormalities.
    The New Zealand medical journal, 1972, Volume: 75, Issue:479

    Topics: Abnormalities, Drug-Induced; Amitriptyline; Female; Humans; Imipramine; Infant, Newborn; Limb Deform

1972
Fetotoxicity.
    The New Zealand medical journal, 1972, Volume: 75, Issue:480

    Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Antidepressive Agents; Female; Human

1972
The toxic potentialities of imipramine.
    Dental anaesthesia and sedation, 1972, Volume: 1, Issue:3

    Topics: Abnormalities, Drug-Induced; Imipramine

1972
Prescriptions of psychotropic drugs by general practitioners. 2. Antidepressants.
    The Medical journal of Australia, 1973, Mar-31, Volume: 1, Issue:13

    Topics: Abnormalities, Drug-Induced; Adjustment Disorders; Adolescent; Adult; Age Factors; Aged; Antidepress

1973
Imipramine and congenital abnormalities.
    Pathologia et microbiologia, 1974, Volume: 40, Issue:1

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Beak; Chick Embryo; Diaphragmatic Eve

1974
The toxicologic and pharmacologic properties of amantadine hydrochloride.
    Toxicology and applied pharmacology, 1969, Volume: 15, Issue:3

    Topics: Abnormalities, Drug-Induced; Acetylcholine; Amantadine; Analgesia; Animals; Arrhythmias, Cardiac; Bl

1969
Imipramine in pregnancy.
    British medical journal, 1972, Mar-18, Volume: 1, Issue:5802

    Topics: Abnormalities, Drug-Induced; Female; Humans; Imipramine; Infant, Newborn; Pregnancy; Time Factors

1972
Malformed infant.
    British medical journal, 1972, Apr-01, Volume: 2, Issue:5804

    Topics: Abnormalities, Drug-Induced; Adult; Cleft Palate; Female; Fetal Death; Humans; Imipramine; Medical R

1972
Imipramine in pregnancy.
    British medical journal, 1972, Apr-29, Volume: 2, Issue:5808

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Amitriptyline; Female; Humans; Imipramine; Infan

1972
Limb deformities associated with iminodibenzyl hydrochloride.
    The Medical journal of Australia, 1972, Mar-04, Volume: 1, Issue:10

    Topics: Abnormalities, Drug-Induced; Ectromelia; Female; Humans; Imipramine; Infant, Newborn; Pregnancy

1972
Limb deformities associated with iminodibenzyl hydrochloride.
    The Medical journal of Australia, 1972, Apr-15, Volume: 1, Issue:16

    Topics: Abnormalities, Drug-Induced; Australia; Female; Humans; Imipramine; Infant, Newborn; Limb Deformitie

1972
Limb deformities associated with iminodibenzyl hydrochloride.
    The Medical journal of Australia, 1972, Apr-29, Volume: 1, Issue:18

    Topics: Abnormalities, Drug-Induced; Australia; Depression; Drug Labeling; Female; Humans; Imipramine; Socie

1972
[False alarm?].
    Medizinische Monatsschrift, 1972, Volume: 26, Issue:4

    Topics: Abnormalities, Drug-Induced; Australia; Drug and Narcotic Control; Drug Prescriptions; Female; Human

1972
Limb deformities associated with iminodibenzyl hydrochloride.
    The Medical journal of Australia, 1972, May-20, Volume: 1, Issue:21

    Topics: Abnormalities, Drug-Induced; Australia; Female; Humans; Imipramine; Information Services; Pregnancy

1972
Imipramine (tofranil).
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Jul-15, Volume: 46, Issue:29

    Topics: Abnormalities, Drug-Induced; Female; Humans; Imipramine; Infant, Newborn; Pregnancy

1972
Imipramine (tofranil).
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Aug-05, Volume: 46, Issue:31

    Topics: Abnormalities, Drug-Induced; Colonic Diseases, Functional; Humans; Imipramine; Male

1972
Imipramine (Tofranil).
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1972, Aug-26, Volume: 46, Issue:34

    Topics: Abnormalities, Drug-Induced; Drug Labeling; Female; Humans; Imipramine; Pregnancy

1972
Limb deformities associated with iminodibenzyl hydrochloride.
    The Medical journal of Australia, 1972, Mar-25, Volume: 1, Issue:13

    Topics: Abnormalities, Drug-Induced; Amitriptyline; Drug and Narcotic Control; Ectromelia; Female; Humans; I

1972
Imipramine and fetal deformities.
    Canadian Medical Association journal, 1972, May-20, Volume: 106, Issue:10

    Topics: Abnormalities, Drug-Induced; Female; Humans; Imipramine; Infant, Newborn; Pregnancy

1972
Limb deformities associated with iminodibenzyl hydrochloride.
    The Medical journal of Australia, 1972, Jul-01, Volume: 2, Issue:1

    Topics: Abnormalities, Drug-Induced; Female; Humans; Imipramine; Infant, Newborn; Limb Deformities, Congenit

1972
[Teratologic studies with imipramine in rats and rabbits. Planning and interpretation of teratologic studies under consideration of the biochemistry and toxicology of test substance].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:10

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Body Weight; Desipramine; Drug Toleranc

1969