Page last updated: 2024-10-29

imipramine and Abnormalities, Autosome

imipramine has been researched along with Abnormalities, Autosome in 7 studies

Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.

Research Excerpts

ExcerptRelevanceReference
"Amitriptyline was found to be nongenotoxic at plasma levels by all the parameters assayed."1.27Genotoxicity evaluation of the tricyclic antidepressants amitriptyline and imipramine using human lymphocyte cultures. ( Ahuja, YR; Saxena, R, 1988)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Madrigal-Bujaidar, E1
Cárdenas García, Y1
Alvarez-González, I1
Fu, TK2
Jarvik, LF2
Yen, FS1
Matsuyama, SS1
Glassman, AH1
Perel, JM1
Maltiz, S1
Saxena, R1
Ahuja, YR1
Bishun, N1
Smith, N1
Williams, DC1
Shapiro, IuL1
Vaĭntrub, MIa1
Grinberg, KN1
Zhurkov, VS1
Roth, B1
Buůhová, S1
Berková, L1

Reviews

1 review available for imipramine and Abnormalities, Autosome

ArticleYear
[Teratogenic and mutagenic effects of anticonvulsive and psychotropic drugs (review of the literature)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1972, Volume: 72, Issue:6

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Anticonvulsants; Antidepressive Agent

1972

Trials

1 trial available for imipramine and Abnormalities, Autosome

ArticleYear
The in vitro effects of imipramine on human chromosomes.
    Mutation research, 1977, Volume: 48, Issue:1

    Topics: Adult; Cells, Cultured; Chromosome Aberrations; Chromosomes; Clinical Trials as Topic; Dose-Response

1977

Other Studies

5 other studies available for imipramine and Abnormalities, Autosome

ArticleYear
Chromosomal aberrations induced by imipramine and desipramine in mouse.
    Human & experimental toxicology, 2010, Volume: 29, Issue:4

    Topics: Animals; Antidepressive Agents, Tricyclic; Bone Marrow Cells; Chromosome Aberrations; Cyclophosphami

2010
Effects of imipramine on chromosomes in psychiatric patients.
    Neuropsychobiology, 1978, Volume: 4, Issue:2

    Topics: Adult; Age Factors; Aged; Aneuploidy; Chromosome Aberrations; Depression; Female; Humans; Imipramine

1978
Genotoxicity evaluation of the tricyclic antidepressants amitriptyline and imipramine using human lymphocyte cultures.
    Environmental and molecular mutagenesis, 1988, Volume: 12, Issue:4

    Topics: Amitriptyline; Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Humans; Imipramine; Lymp

1988
Lack of in vivo cytogenetic effects of imipramine in rats.
    Teratology, 1974, Volume: 10, Issue:2

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Chromosomes; Female; Imipramine; Ma

1974
Familial sleep paralysis.
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1968, Volume: 102, Issue:2

    Topics: Adult; Aged; Chromosome Aberrations; Chromosome Disorders; Female; Follow-Up Studies; Humans; Imipra

1968