imipramine has been researched along with ADDH in 61 studies
Imipramine: The prototypical tricyclic antidepressant. It has been used in major depression, dysthymia, bipolar depression, attention-deficit disorders, agoraphobia, and panic disorders. It has less sedative effect than some other members of this therapeutic group.
imipramine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine substituted by a 3-(dimethylamino)propyl group at the nitrogen atom.
Excerpt | Relevance | Reference |
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"High-affinity [3H]imipramine binding to platelets was investigated in 11 boys with attention deficit disorder and hyperactivity (ADDH) before and after 28 days of methylphenidate (MPH) treatment, and the results were compared to [3H]imipramine binding parameters (Kd, Bmax) of 10 age-matched normal boys." | 7.67 | Imipramine binding to platelets of children with attention deficit disorder with hyperactivity. ( Bernhout, E; Rehavi, M; Tyano, S; Weitz, R; Weizman, A, 1988) |
" Combination therapy with desmopressin and oxybutynin is a feasible, safe and effective treatment for nocturnal enuresis in these children." | 5.12 | Treatment of nocturnal enuresis in children with attention deficit hyperactivity disorder. ( Abu-Arafeh, W; Chertin, B; Farkas, A; Koulikov, D; Mor, Y; Shenfeld, OZ, 2007) |
"High-affinity [3H]imipramine binding to platelets was investigated in 11 boys with attention deficit disorder and hyperactivity (ADDH) before and after 28 days of methylphenidate (MPH) treatment, and the results were compared to [3H]imipramine binding parameters (Kd, Bmax) of 10 age-matched normal boys." | 3.67 | Imipramine binding to platelets of children with attention deficit disorder with hyperactivity. ( Bernhout, E; Rehavi, M; Tyano, S; Weitz, R; Weizman, A, 1988) |
"Binding characteristics of tritiated imipramine on blood platelets were determined in daytime hospitalized prepubertal children who had mixed diagnoses of conduct disorder (CD) plus attention deficit disorder hyperactivity (ADDH) and in inpatient adolescents who had a history of aggressive behavior." | 3.67 | Reduction of (3H)-imipramine binding sites on platelets of conduct-disordered children. ( Behar, D; Bridger, WH; Pollock, L; Stoff, DM; Vitiello, B, 1987) |
"The imipramine dosage was significantly higher in the combined treatment group than in the imipramine-only group." | 2.67 | Possible influence of carbamazepine on plasma imipramine concentrations in children with attention deficit hyperactivity disorder. ( Brown, CS; Cold, JA; Froemming, JH; Jabbour, JT; Self, TH; Wells, BG, 1990) |
" Imipramine exerted negative dose-response effects on motor performance (motor speed, motor pursuit), while it improved hyperactive behavior and attention and raised the heart rate slightly." | 2.66 | Motor performance in hyperactive children treated with imipramine. ( Evans, RW; Gualtieri, CT, 1988) |
" This review focuses on the tolerability, occurrence of adverse events, precautions required to prevent severe adverse events, and essential pharmacological interaction in the treatment of ADHD symptoms by non-stimulants." | 2.43 | The safety of non-stimulant agents for the treatment of attention-deficit hyperactivity disorder. ( Banaschewski, T; Heise, CA; Himpel, S; Rothenberger, A, 2005) |
" Thirty-two reports (29 studies) evaluated adverse effects of drug therapy; many of the side effects associated with stimulant use appear to be relatively mild and of short duration and to respond to dosing or timing adjustments." | 2.40 | Treatment of attention-deficit/hyperactivity disorder. ( Boyle, M; Cunningham, C; Jadad, AR; Kim, M; Schachar, R, 1999) |
"As to the treatment of depressive disorder, school phobia and obsessive-compulsive disorder in children and adolescents, no controlled empirical studies on combined therapies exist." | 2.38 | Pharmacotherapy and behaviour therapy--competition or cooperation? ( van Engeland, H, 1993) |
"Those disorders discussed are attention deficit disorder, conduct disorders, anxiety disorders, sleep disorders, schizophrenia, autism, Tourette's syndrome, mental retardation, depressive illness, manic depressive illness, eating disorders, and enuresis." | 2.37 | Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1). ( McDaniel, KD, 1986) |
"No significant arrhythmias or tachycardias were observed." | 1.29 | ECG changes in pediatric patients on tricyclic antidepressants, desipramine, and imipramine. ( Giuffre, RM; Johnson, A; O'Malley, K, 1996) |
"Treatment with imipramine decreased auditory P300 latencies and increased auditory P300 amplitudes." | 1.29 | Prolonged P300 latency in attention deficit hyperactivity disorder predicts poor response to imipramine. ( Persky, B; Sangal, JM; Sangal, RB, 1996) |
"Imipramine also improved the boy's insomnia and enuresis, whereas methylphenidate caused an overall worsening of his condition." | 1.28 | Imipramine treatment of ADHD in a fragile X child. ( Hall, BD; Heffron, WM; Hilton, DK; Johnson, GL; Martin, CA, 1991) |
"A subcategory of patients with borderline personality disorder (BPD) who also meet criteria for attention deficit disorder (ADD) has recently been described." | 1.27 | Use of imipramine for attention deficit disorder in a borderline patient. ( Denton, C; Satel, S; Southwick, S, 1988) |
"Many children with attention deficit disorder also meet DSM-III criteria for separation anxiety disorder, the symptoms of which cluster in four of the nine criteria." | 1.26 | An indication for use of imipramine in attention deficit disorder. ( Cox, WH, 1982) |
"The authors treated two children with Gilles de la Tourette's disease and one child with a probable combination of Gilles de la Tourette's disease and minimal brain dysfunction with methylphenidate, which resulted in exacerbation of symptoms." | 1.26 | The use of methylphenidate and imipramine in Gilles de la Tourette's disease in children. ( Fras, I; Karlavage, J, 1977) |
" No correlations were found between dosage level and changes in weight and height percentiles." | 1.26 | Growth of hyperkinetic children taking methylphenidate, dextroamphetamine, or imipramine/desipramine. ( Gross, MD, 1976) |
"Minimal brain dysfunction is a neurodevelopmental disorder which can be found in nearly 20% of school children." | 1.26 | Minimal brain dysfunction/specific learning disability: a clinical approach for the primary physician. ( Levy, HB, 1976) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 32 (52.46) | 18.7374 |
1990's | 17 (27.87) | 18.2507 |
2000's | 9 (14.75) | 29.6817 |
2010's | 3 (4.92) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Preskorn, SH | 2 |
Topczewski, A | 1 |
Himpel, S | 1 |
Banaschewski, T | 1 |
Heise, CA | 1 |
Rothenberger, A | 1 |
Terranova, JP | 1 |
Chabot, C | 1 |
Barnouin, MC | 1 |
Perrault, G | 1 |
Depoortere, R | 1 |
Griebel, G | 1 |
Scatton, B | 1 |
Cak, HT | 1 |
Cetin, FC | 1 |
Tahiroglu, AY | 1 |
Avci, A | 1 |
Volkers, AC | 1 |
Heerdink, ER | 1 |
van Dijk, L | 1 |
Chertin, B | 1 |
Koulikov, D | 1 |
Abu-Arafeh, W | 1 |
Mor, Y | 1 |
Shenfeld, OZ | 1 |
Farkas, A | 1 |
Ghanizadeh, A | 1 |
Clarke, AR | 1 |
Barry, RJ | 1 |
McCarthy, R | 1 |
Selikowitz, M | 1 |
Johnstone, SJ | 1 |
Wiener, JM | 2 |
Gauthier, M | 1 |
Pozzi, M | 1 |
Hartley, L | 1 |
Huessy, HR | 2 |
Winsberg, BG | 1 |
Kupietz, SS | 1 |
Yepes, LE | 1 |
Goldstein, S | 1 |
Nissen, G | 1 |
Pappas, BA | 1 |
Vogel, RA | 1 |
Wilson, JH | 1 |
Mueller, RA | 1 |
Breese, GR | 1 |
Cox, WH | 1 |
White, JH | 1 |
St Dennis, C | 1 |
Synoground, G | 1 |
Alderton, HR | 1 |
Simeon, JG | 1 |
Wiggins, DM | 1 |
Williams, E | 1 |
Burke, MS | 1 |
Josephson, A | 1 |
Lightsey, A | 1 |
van Engeland, H | 1 |
Johnson, A | 1 |
Giuffre, RM | 1 |
O'Malley, K | 1 |
Maynard, GL | 1 |
Soni, P | 1 |
Arnold, LE | 1 |
Abikoff, HB | 1 |
Cantwell, DP | 1 |
Conners, CK | 1 |
Elliott, G | 1 |
Greenhill, LL | 1 |
Hechtman, L | 1 |
Hinshaw, SP | 1 |
Hoza, B | 1 |
Jensen, PS | 1 |
Kraemer, HC | 1 |
March, JS | 1 |
Newcorn, JH | 1 |
Pelham, WE | 1 |
Richters, JE | 1 |
Schiller, E | 1 |
Severe, JB | 1 |
Swanson, JM | 1 |
Vereen, D | 1 |
Wells, KC | 1 |
Sangal, JM | 1 |
Sangal, RB | 1 |
Persky, B | 1 |
Guardiola, A | 1 |
Terra, AR | 1 |
Pereira, KR | 1 |
Rotta, NT | 1 |
Jadad, AR | 1 |
Boyle, M | 1 |
Cunningham, C | 1 |
Kim, M | 1 |
Schachar, R | 1 |
Hill, P | 1 |
Taylor, E | 1 |
Millichap, JG | 1 |
Fras, I | 1 |
Karlavage, J | 1 |
Rybak, WS | 1 |
Bellak, L | 2 |
Gross, MD | 2 |
Mann, HB | 1 |
Greenspan, SI | 1 |
Palmer, S | 1 |
Rapoport, JL | 1 |
Quinn, PO | 1 |
Levy, HB | 1 |
Holt, KG | 1 |
Weinberg, WA | 1 |
Brumback, RA | 1 |
Marazziti, D | 1 |
Conti, L | 1 |
Hilton, DK | 1 |
Martin, CA | 1 |
Heffron, WM | 1 |
Hall, BD | 1 |
Johnson, GL | 1 |
Tingelstad, JB | 1 |
Brown, CS | 1 |
Wells, BG | 1 |
Cold, JA | 1 |
Froemming, JH | 1 |
Self, TH | 1 |
Jabbour, JT | 1 |
McDaniel, KD | 1 |
Weizman, A | 1 |
Bernhout, E | 1 |
Weitz, R | 1 |
Tyano, S | 1 |
Rehavi, M | 1 |
Stoff, DM | 1 |
Pollock, L | 1 |
Vitiello, B | 1 |
Behar, D | 1 |
Bridger, WH | 1 |
Dillon, DC | 1 |
Salzman, IJ | 1 |
Schulsinger, DA | 1 |
Gualtieri, CT | 1 |
Evans, RW | 1 |
Satel, S | 1 |
Southwick, S | 2 |
Denton, C | 1 |
Pliszka, SR | 1 |
Satel, SL | 1 |
Omenn, GS | 1 |
Peters, JE | 1 |
Silver, LB | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Multimodal Treatment Study of Children With ADHD[NCT00000388] | Phase 4 | 0 participants | Interventional | 1998-09-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
13 reviews available for imipramine and ADDH
Article | Year |
---|---|
Clinical psychopharmacology and medical malpractice: the four Ds.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; C | 2014 |
The safety of non-stimulant agents for the treatment of attention-deficit hyperactivity disorder.
Topics: Adrenergic alpha-Agonists; Adult; Antidepressive Agents, Tricyclic; Atomoxetine Hydrochloride; Atten | 2005 |
Psychotropic drug therapy in children and adolescents.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Anxiety, Separation; Attention D | 1982 |
Stimulant medications in adults with attention deficit disorder.
Topics: Adolescent; Adult; Amitriptyline; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys | 1984 |
Psychopharmacology in childhood disorders.
Topics: Anorexia Nervosa; Antidepressive Agents; Antipsychotic Agents; Anxiety, Separation; Attention Defici | 1984 |
Tricyclic medication in children and the QT interval: case report and discussion.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Chil | 1995 |
Pharmacotherapy and behaviour therapy--competition or cooperation?
Topics: Adolescent; Adolescent Psychiatry; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; | 1993 |
Treatment of attention-deficit/hyperactivity disorder.
Topics: Adrenergic Uptake Inhibitors; Adult; Antidepressive Agents, Tricyclic; Attention Deficit Disorder wi | 1999 |
An auditable protocol for treating attention deficit/hyperactivity disorder.
Topics: Algorithms; Attention Deficit Disorder with Hyperactivity; Child; Clinical Protocols; Clinical Trial | 2001 |
The myth of attention deficit-hyperactivity disorder: symptoms resulting from multiple causes.
Topics: Arousal; Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Child, Pres | 1992 |
Pharmacologic treatment of psychiatric and neurodevelopmental disorders in children and adolescents (Part 1).
Topics: Adolescent; Aggression; Antidepressive Agents; Antipsychotic Agents; Anxiety, Separation; Attention | 1986 |
Genetic issues in the syndrome of minimal brain dysfunction.
Topics: Attention Deficit Disorder with Hyperactivity; Dextroamphetamine; Diseases in Twins; Female; Humans; | 1973 |
The neurologic learning disability syndrome.
Topics: Anorexia Nervosa; Anxiety; Attention; Attention Deficit Disorder with Hyperactivity; Brain Damage, C | 1971 |
10 trials available for imipramine and ADDH
Article | Year |
---|---|
Treatment of nocturnal enuresis in children with attention deficit hyperactivity disorder.
Topics: Antidepressive Agents, Tricyclic; Antidiuretic Agents; Attention Deficit Disorder with Hyperactivity | 2007 |
Effects of imipramine hydrochloride on the EEG of children with Attention-Deficit/Hyperactivity Disorder who are non-responsive to stimulants.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Case-Co | 2008 |
Stimulant medications in adults with attention deficit disorder.
Topics: Adolescent; Adult; Amitriptyline; Attention Deficit Disorder with Hyperactivity; Central Nervous Sys | 1984 |
Ineffectiveness of imipramine in children who fail to respond to methylphenidate.
Topics: Aggression; Attention; Attention Deficit Disorder with Hyperactivity; Child; Clinical Trials as Topi | 1980 |
National Institute of Mental Health Collaborative Multimodal Treatment Study of Children with ADHD (the MTA). Design challenges and choices.
Topics: Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Child; Clinical Protocols; Combined | 1997 |
[Use of drugs in attention deficit hyperactivity disorders].
Topics: Analysis of Variance; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivit | 1997 |
Food additives and hyperactivity.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Clinical Trials as Topic; Feeding Behavior; Fo | 1975 |
Caffeine in the treatment of children with minimal brain dysfunction or hyperkinetic syndrome.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Caffeine; Child; Child, Preschool; Clinic | 1975 |
Possible influence of carbamazepine on plasma imipramine concentrations in children with attention deficit hyperactivity disorder.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Carbamazepine; Child; Child, Preschool; D | 1990 |
Motor performance in hyperactive children treated with imipramine.
Topics: Arousal; Attention; Attention Deficit Disorder with Hyperactivity; Child; Clinical Trials as Topic; | 1988 |
39 other studies available for imipramine and ADDH
Article | Year |
---|---|
Attention deficit and hyperactivity disorder: a therapeutic option.
Topics: Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity | 2014 |
Inadvertent fatal imipramine poisoning of a child: what happened to Tommy?
Topics: Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Child; Dose-Respons | 2011 |
SSR181507, a dopamine D(2) receptor antagonist and 5-HT(1A) receptor agonist, alleviates disturbances of novelty discrimination in a social context in rats, a putative model of selective attention deficit.
Topics: Age Factors; Animals; Attention Deficit Disorder with Hyperactivity; Behavior, Animal; Clozapine; De | 2005 |
Reboxetine use in the treatment of attention-deficit/hyperactivity disorder.
Topics: Adolescent; Antidepressive Agents; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with | 2006 |
Polypharmacy and EPS in a child; a case report.
Topics: Attention Deficit Disorder with Hyperactivity; Benztropine; Bipolar Disorder; Child; Comorbidity; Do | 2007 |
Antidepressant use and off-label prescribing in children and adolescents in Dutch general practice (2001-2005).
Topics: Adolescent; Adrenergic Uptake Inhibitors; Antidepressive Agents, Second-Generation; Antidepressive A | 2007 |
Knowledge of pharmacists regarding ritalin and ADHD and their attitude towards the use of ritalin to treat ADHD.
Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Education, Pharmacy; Education, Ph | 2008 |
Hyperactivity, drugs and attention deficit.
Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Femal | 1984 |
Use of tricyclics.
Topics: Amitriptyline; Attention Deficit Disorder with Hyperactivity; Child; Humans; Imipramine | 1984 |
[Psychotropic drugs for children].
Topics: Amitriptyline; Anxiety Disorders; Attention Deficit Disorder with Hyperactivity; Benzodiazepines; Ce | 1981 |
Drug alterations of punished responding after chlordiazepoxide: possible screen for agents useful in minimal brain dysfunction.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Bupropion; Chlordiazepoxide; Conditioning, O | 1981 |
Imipramine for attention deficit disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Humans; Imipramine | 1983 |
An indication for use of imipramine in attention deficit disorder.
Topics: Anxiety, Separation; Attention Deficit Disorder with Hyperactivity; Child; Humans; Imipramine; Male; | 1982 |
The hyperactive child in adolescence: some pharmacologic approaches.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Child Behavior Disorder | 1981 |
Imipramine.
Topics: Adrenergic Uptake Inhibitors; Attention Deficit Disorder with Hyperactivity; Child; Drug Monitoring; | 1995 |
World wide use of psychotropic drugs in child and adolescent psychiatric disorders.
Topics: Adolescent; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Canada; Child; Chi | 1995 |
Combined methylphenidate and imipramine complication.
Topics: Aggression; Anemia; Attention Deficit Disorder with Hyperactivity; Blood Cells; Child; Drug Synergis | 1995 |
ECG changes in pediatric patients on tricyclic antidepressants, desipramine, and imipramine.
Topics: Adolescent; Alberta; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Attention Deficit Disor | 1996 |
Thioridazine interferences with imipramine metabolism and measurement.
Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivit | 1996 |
Prolonged P300 latency in attention deficit hyperactivity disorder predicts poor response to imipramine.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Brain M | 1996 |
Growth of hyperkinetic children taking methylphenidate, dextroamphetamine, or imipramine/desipramine.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Desipramine; Dextroamphetamine; Growth; Humans | 1978 |
The use of methylphenidate and imipramine in Gilles de la Tourette's disease in children.
Topics: Acute Disease; Attention Deficit Disorder with Hyperactivity; Catecholamines; Child; Humans; Imipram | 1977 |
More adult brain dysfunction.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Brain Damage, Chronic; Humans; Imipramine; Int | 1977 |
A possible subgroup of the schizophrenic syndrome and implications for treatment.
Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Diazepam; Dominance, Cerebral; Dys | 1976 |
Growth of hyperkinetic children taking methylphenidate, dextroamphetamine, or imipramine/desipramine.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Dextroamphetamin | 1976 |
The identification and treatment of adult brain dysfunction.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Dextroamphetamine; Female; Humans; Imipramine; | 1976 |
Minimal brain dysfunction/specific learning disability: a clinical approach for the primary physician.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Child Behavior Disorders; Dextroamphetamine; F | 1976 |
Growth deficits and desipramine.
Topics: Appetite; Attention Deficit Disorder with Hyperactivity; Body Weight; Child; Depressive Disorder; De | 1992 |
Aggression, hyperactivity and platelet imipramine binding.
Topics: Adult; Aggression; Attention Deficit Disorder with Hyperactivity; Brain; Carrier Proteins; Female; H | 1991 |
Imipramine treatment of ADHD in a fragile X child.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Dose-Response Relationship, Drug; Drug Adminis | 1991 |
The cardiotoxicity of the tricyclics.
Topics: Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Attention Deficit Disorder with Hyperactivit | 1991 |
Imipramine binding to platelets of children with attention deficit disorder with hyperactivity.
Topics: Attention Deficit Disorder with Hyperactivity; Blood Platelets; Carrier Proteins; Child; Humans; Imi | 1988 |
Reduction of (3H)-imipramine binding sites on platelets of conduct-disordered children.
Topics: Adolescent; Adolescent Behavior; Aggression; Attention Deficit Disorder with Hyperactivity; Biomarke | 1987 |
The use of imipramine in Tourette's syndrome and attention deficit disorder: case report.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Dextroamphe | 1985 |
Use of imipramine for attention deficit disorder in a borderline patient.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Borderline Personality Disorder; Humans; Imipr | 1988 |
Tricyclic antidepressants in the treatment of children with attention deficit disorder.
Topics: Antidepressive Agents, Tricyclic; Attention; Attention Deficit Disorder with Hyperactivity; Child; H | 1987 |
Consequences of abrupt reduction of chronic symptoms.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Chronic Disease; Female; Humans; Imipramine; M | 1987 |
ADD psychosis as a separate entity.
Topics: Attention Deficit Disorder with Hyperactivity; Bipolar Disorder; Diagnosis, Differential; Female; Hu | 1985 |
Minimal brain dysfunctions in children.
Topics: Amphetamine; Attention; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Comm | 1974 |