Compounds > imipenem, anhydrous
Page last updated: 2024-08-26

imipenem, anhydrous and Critical Illness

imipenem, anhydrous has been researched along with Critical Illness in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.50)18.2507
2000's12 (30.00)29.6817
2010's16 (40.00)24.3611
2020's11 (27.50)2.80

Authors

AuthorsStudies
Ariza, J; Dominguez, MA; Gudiol, F; Guzmán, A; Peña, C; Pujol, M; Suarez, C; Tubau, F1
Bulitta, JB; Drusano, GL; Glauner, AK; Kinzig-Schippers, M; Pfister, W; Sakka, SG; Sörgel, F1
André, P; Asner, SA; Buclin, T; Csajka, C; Dao, K; Decosterd, LA; Fuchs, A; Giannoni, E; Guidi, M; Marchetti, O; Pfister, M; Widmer, N1
Chung, KK; DeLuca, JP; Kress, AT; Reed, T; Selig, DJ; Stewart, IJ1
Amadesi, S; Ambretti, S; Gaibani, P; Lazzarotto, T1
Fratoni, AJ; Kuti, JL; Mah, JW; Nicolau, DP1
Liu, G; Qi, Y1
Becker, P; Chausse, J; Gous, A; Milne, M; Mitton, B; Paruk, F; Said, M1
de Velde, F; de Winter, BCM; Harbarth, S; Huttner, A; Koch, BCP; Mouton, JW; Neely, MN; van Gelder, T; von Dach, E; Yamada, WM1
Dang, ZL; Li, B; Qin, HY; Rao, Z; Wei, YH; Wu, XA; Zhu, L1
Bai, J; Duan, M; Li, X; Li, Z; Shen, S; Wen, A1
Jaruratanasirikul, S; Nawakitrangsan, M; Samaeng, M; Vattanavanit, V; Wongpoowarak, W1
Boonpeng, A; Jaruratanasirikul, S; Nawakitrangsan, M; Samaeng, M1
Abdellatif, S; Abdennebi, C; Ben Lakhal, S; Daly, F; Nasri, R; Touil, Y; Trifi, A1
Li, S; Xie, F1
Jaruratanasirikul, S; Nawakitrangsan, M; Samaeng, M; Sriwiriyajan, S; Vattanavanit, V1
Aeinlang, N; Jaruratanasirikul, S; Jullangkoon, M; Wongpoowarak, W1
Aduroja, OA; Afshartous, D; Amde, M; Bauer, SR; Connor, MJ; Fissell, WH; Groszek, JJ; Salem, C1
Chen, CL; Chiu, CH; Huang, CW; Lee, HY; Wu, SR1
Al-Tawfiq, JA; Dib, J; Memish, ZA; Momattin, H1
Armand-Lefevre, L; Burdet, C; Couffignal, C; Foucrier, A; Laouénan, C; Massias, L; Mentré, F; Pajot, O; Wolff, M1
Balík, M; Lipš, M; Siller, M; Strojil, J; Suchánková, H; Urbánek, K1
Decosterd, LA; Eggimann, P; Fournier, A; Marchetti, O; Pagani, JL; Pannatier, A; Que, YA; Revelly, JP; Voirol, P1
Bai, J; Cheng, S; Duan, M; Li, R; Li, Z; Wen, A; Yu, J1
Lipš, M; Neely, MN; Strojil, J; Suchánková, H; Urbánek, K1
Couet, W; Dahyot-Fizelier, C; Laksiri, L; Lefeuvre, S; Marchand, S; Mimoz, O; Sawchuk, RJ1
Harris, AD; Hsiao, WW; Johnson, JK; Rasko, DA; Stine, OC; Thom, KA1
Ajao, AO; Furuno, JP; Harris, AD; Johnson, JK; Lee, MS; Ranke, TD; Robinson, G; Venezia, RA1
Gonçalves-Pereira, J; Póvoa, P1
Aissa, N; Calmette, MJ; Herve, J; Legrand, P; Renaud, B; Roupie, E; Santin, A; Sorkine, M1
Adembri, C; De Gaudio, AR; Fallani, S; Livi, P; Mazzei, T; Novelli, A1
Abraham, E; Fish, DN; Teitelbaum, I1
d'Escrivan, T; Devos, P; Dubreuil, L; Georges, H; Kipnis, E; Leroy, O1
Alvarez-Lerma, F; Castillo, F; Cerdá, E; Insausti, J; Martínez-Pellús, A; Olaechea, P; Palomar, M1
Bille, J; Bugnon, D; Cotting, J; Décosterd, L; Giannoni, E; Majcherczyk, P; Moessinger, A; Moreillon, P; Zanetti, G1
Chang, CM; Chuang, YC; Ko, WC; Lee, HC; Lee, NY; Wang, CL; Wang, LR; Yu, WL1
Bodin, M; Couet, W; Dahyot, C; Debeane, B; Marchand, S; Mimoz, O1
Ebira, H; Ikeda, Y; Kihara, M; Masumori, S; Shibata, K; Shionoiri, H; Shiratori, K; Takagi, N; Ueda, S; Umemura, S1
Daras, M; Hauser, WA; Koppel, BS; Politis, C; van Duin, D1
Bräutigam, L; Geisslinger, G; Kirschbaum, A; Lötsch, J; Schmidtko, A; Tegeder, I1

Reviews

1 review(s) available for imipenem, anhydrous and Critical Illness

ArticleYear
Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactams.
    Critical care (London, England), 2011, Volume: 15, Issue:5

    Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Cefpirome; Ceftazidime; Cephalosporins; Critical Illness; Humans; Imipenem; Infections; Meropenem; Piperacillin; Thienamycins

2011

Trials

8 trial(s) available for imipenem, anhydrous and Critical Illness

ArticleYear
Population pharmacokinetics and pharmacodynamics of continuous versus short-term infusion of imipenem-cilastatin in critically ill patients in a randomized, controlled trial.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Cilastatin; Critical Illness; Cross Infection; Drug Combinations; Female; Humans; Imipenem; Infusions, Intravenous; Logistic Models; Male; Middle Aged; Monte Carlo Method; Protease Inhibitors; Tandem Mass Spectrometry; Treatment Outcome

2007
Pharmacokinetic and Pharmacodynamic Analysis of Critically Ill Patients Undergoing Continuous Renal Replacement Therapy With Imipenem.
    Clinical therapeutics, 2020, Volume: 42, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Continuous Renal Replacement Therapy; Critical Illness; Female; Humans; Imipenem; Male; Microbial Sensitivity Tests; Middle Aged; Models, Biological; Young Adult

2020
Pharmacodynamics of imipenem in critically ill patients with ventilator-associated pneumonia.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2013, Volume: 96, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Critical Illness; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Imipenem; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Pneumonia, Ventilator-Associated; Respiration, Artificial; Treatment Outcome

2013
Population pharmacokinetics of imipenem in critically ill patients with suspected ventilator-associated pneumonia and evaluation of dosage regimens.
    British journal of clinical pharmacology, 2014, Volume: 78, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Critical Illness; Dose-Response Relationship, Drug; Female; Gram-Negative Bacteria; Humans; Imipenem; Infusions, Intravenous; Male; Middle Aged; Models, Biological; Models, Statistical; Monte Carlo Method; Pneumonia, Ventilator-Associated; Prospective Studies

2014
Pharmacokinetics of imipenem in critically ill patients during empirical treatment of nosocomial pneumonia: a comparison of 0.5-h and 3-h infusions.
    International journal of antimicrobial agents, 2014, Volume: 44, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Critical Illness; Cross Infection; Female; Humans; Imipenem; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Plasma; Pneumonia, Bacterial; Young Adult

2014
Pharmacokinetic evaluation of meropenem and imipenem in critically ill patients with sepsis.
    Clinical pharmacokinetics, 2005, Volume: 44, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Area Under Curve; Critical Illness; Female; Humans; Imipenem; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Sepsis; Thienamycins

2005
Pharmacokinetics and pharmacodynamics of imipenem during continuous renal replacement therapy in critically ill patients.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:6

    Topics: Adult; Aged; Anti-Bacterial Agents; Cilastatin; Critical Illness; Drug Therapy, Combination; Female; Hemodiafiltration; Hemofiltration; Humans; Imipenem; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Protease Inhibitors; Renal Replacement Therapy

2005
Application of basic pharmacokinetic concepts to analysis of microdialysis data: illustration with imipenem muscle distribution.
    Clinical pharmacokinetics, 2008, Volume: 47, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Area Under Curve; Chromatography, High Pressure Liquid; Critical Illness; Extracellular Space; Female; Humans; Imipenem; Male; Microdialysis; Middle Aged; Muscle, Skeletal; Time Factors; Tissue Distribution

2008

Other Studies

31 other study(ies) available for imipenem, anhydrous and Critical Illness

ArticleYear
Effects of carbapenem exposure on the risk for digestive tract carriage of intensive care unit-endemic carbapenem-resistant Pseudomonas aeruginosa strains in critically ill patients.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:6

    Topics: Adult; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Carrier State; Critical Illness; Endemic Diseases; Female; Gastrointestinal Tract; Humans; Imipenem; Incidence; Intensive Care Units; Male; Middle Aged; Pharynx; Pseudomonas aeruginosa; Pseudomonas Infections; Rectum; Risk Factors

2007
Dosing strategies of imipenem in neonates based on pharmacometric modelling and simulation.
    The Journal of antimicrobial chemotherapy, 2022, 02-02, Volume: 77, Issue:2

    Topics: Anti-Bacterial Agents; Computer Simulation; Critical Illness; Gestational Age; Humans; Imipenem; Infant; Infant, Newborn

2022
Hemoperfusion with Seraph 100 Microbind Affinity Blood Filter Unlikely to Require Increased Antibiotic Dosing: A Simulations Study Using a Pharmacokinetic/Pharmacodynamic Approach.
    Blood purification, 2023, Volume: 52, Issue:1

    Topics: Anti-Bacterial Agents; Critical Illness; Gentamicins; Hemoperfusion; Humans; Imipenem; Meropenem; Vancomycin

2023
Genome characterization of a Klebsiella pneumoniae co-producing OXA-181 and KPC-121 resistant to ceftazidime/avibactam, meropenem/vaborbactam, imipenem/relebactam and cefiderocol isolated from a critically ill patient.
    Journal of global antimicrobial resistance, 2022, Volume: 30

    Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Boronic Acids; Cefiderocol; Ceftazidime; Cephalosporins; Critical Illness; Humans; Imipenem; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests

2022
Imipenem/cilastatin/relebactam pharmacokinetics in critically ill patients with augmented renal clearance.
    The Journal of antimicrobial chemotherapy, 2022, 10-28, Volume: 77, Issue:11

    Topics: Anti-Bacterial Agents; Cilastatin; Critical Illness; Humans; Imipenem

2022
A UPLC-MS/MS method for simultaneous determination of eight special-grade antimicrobials in human plasma and application in TDM.
    Journal of pharmaceutical and biomedical analysis, 2022, Oct-25, Volume: 220

    Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Chromatography, Liquid; Critical Illness; Drug Monitoring; Humans; Imipenem; Linezolid; Meropenem; Micafungin; Reproducibility of Results; Tandem Mass Spectrometry; Teicoplanin; Tigecycline; Vancomycin; Voriconazole

2022
Evaluating the usefulness of the estimated glomerular filtration rate for determination of imipenem dosage in critically ill patients.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2022, 08-30, Volume: 112, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albumins; Anti-Bacterial Agents; Cilastatin, Imipenem Drug Combination; Creatinine; Critical Illness; Female; Glomerular Filtration Rate; Humans; Imipenem; Male; Middle Aged; Renal Insufficiency, Chronic; Sepsis; South Africa; Young Adult

2022
Population Pharmacokinetics of Imipenem in Critically Ill Patients: A Parametric and Nonparametric Model Converge on CKD-EPI Estimated Glomerular Filtration Rate as an Impactful Covariate.
    Clinical pharmacokinetics, 2020, Volume: 59, Issue:7

    Topics: Adult; Anti-Bacterial Agents; Critical Illness; Female; Glomerular Filtration Rate; Humans; Imipenem; Male; Middle Aged; Renal Insufficiency, Chronic

2020
Determination of Total and Unbound Meropenem, Imipenem/Cilastatin, and Cefoperazone/Sulbactam in Human Plasma: Application for Therapeutic Drug Monitoring in Critically Ill Patients.
    Therapeutic drug monitoring, 2020, Volume: 42, Issue:4

    Topics: Cefoperazone; Chromatography, High Pressure Liquid; Cilastatin; Cilastatin, Imipenem Drug Combination; Critical Illness; Drug Monitoring; Humans; Imipenem; Meropenem; Plasma; Sulbactam; Tandem Mass Spectrometry

2020
Pharmacokinetics and Monte Carlo Dosing Simulations of Imipenem in Critically Ill Patients with Life-Threatening Severe Infections During Support with Extracorporeal Membrane Oxygenation.
    European journal of drug metabolism and pharmacokinetics, 2020, Volume: 45, Issue:6

    Topics: Adolescent; Adult; Aged; Algorithms; Anti-Bacterial Agents; Area Under Curve; Bacterial Infections; Computer Simulation; Critical Illness; Extracorporeal Membrane Oxygenation; Female; Humans; Imipenem; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Monte Carlo Method; Young Adult

2020
NONMEM population pharmacokinetics and Monte Carlo dosing simulations of imipenem in critically ill patients with life-threatening severe infections during support with or without extracorporeal membrane oxygenation in an intensive care unit.
    Pharmacotherapy, 2021, Volume: 41, Issue:7

    Topics: Anti-Bacterial Agents; Bacterial Infections; Critical Illness; Dose-Response Relationship, Drug; Extracorporeal Membrane Oxygenation; Humans; Imipenem; Intensive Care Units; Monte Carlo Method

2021
Appropriateness of empiric antimicrobial therapy with imipenem/colistin in severe septic patients: observational cohort study.
    Annals of clinical microbiology and antimicrobials, 2018, Nov-16, Volume: 17, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Cohort Studies; Colistin; Critical Illness; Female; Humans; Imipenem; Intensive Care Units; Male; Middle Aged; Prospective Studies; Sepsis

2018
Population pharmacokinetics and simulations of imipenem in critically ill patients undergoing continuous renal replacement therapy.
    International journal of antimicrobial agents, 2019, Volume: 53, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Critical Illness; Diuresis; Female; Humans; Imipenem; Male; Middle Aged; Models, Theoretical; Monte Carlo Method; Renal Replacement Therapy

2019
Pharmacokinetics of Imipenem in Critically Ill Patients with Life-threatening Severe Infections During Support with Extracorporeal Membrane Oxygenation.
    Clinical drug investigation, 2019, Volume: 39, Issue:8

    Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Critical Illness; Extracorporeal Membrane Oxygenation; Female; Heart Failure; Humans; Imipenem; Male

2019
Pharmacokinetics and pharmacodynamics of imipenem and meropenem in critically ill patients treated with continuous venovenous hemodialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2014, Volume: 63, Issue:1

    Topics: Anti-Bacterial Agents; Critical Illness; Drug Dosage Calculations; Female; Gram-Negative Bacterial Infections; Humans; Imipenem; Male; Medication Errors; Meropenem; Metabolic Clearance Rate; Middle Aged; Renal Dialysis; Thienamycins

2014
Risk factors and outcome analysis of acinetobacter baumannii complex bacteremia in critical patients.
    Critical care medicine, 2014, Volume: 42, Issue:5

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Bacteremia; Bacterial Proteins; beta-Lactam Resistance; Critical Illness; Electrophoresis, Gel, Pulsed-Field; Female; Humans; Imipenem; Intensive Care Units; Kaplan-Meier Estimate; Male; Multivariate Analysis; Pneumonia, Ventilator-Associated; Polymerase Chain Reaction; Retrospective Studies; Risk Factors; RNA, Ribosomal, 16S; Tertiary Care Centers; Treatment Outcome

2014
Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2014, Volume: 20

    Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Coronavirus; Coronavirus Infections; Critical Illness; Diabetes Mellitus; Female; Humans; Hypertension; Imipenem; Interferon alpha-2; Interferon-alpha; Male; Middle Aged; Recombinant Proteins; Renal Insufficiency, Chronic; Respiration, Artificial; Respiratory Tract Infections; Retrospective Studies; Ribavirin; Treatment Outcome; Young Adult

2014
Impact of the introduction of real-time therapeutic drug monitoring on empirical doses of carbapenems in critically ill burn patients.
    Burns : journal of the International Society for Burn Injuries, 2015, Volume: 41, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Body Surface Area; Burn Units; Burns; Carbapenems; Cilastatin; Cilastatin, Imipenem Drug Combination; Cohort Studies; Computer Systems; Critical Illness; Drug Combinations; Drug Monitoring; Female; Humans; Imipenem; Length of Stay; Male; Meropenem; Middle Aged; Retrospective Studies; Thienamycins; Young Adult

2015
Clinical Validation of Therapeutic Drug Monitoring of Imipenem in Spent Effluent in Critically Ill Patients Receiving Continuous Renal Replacement Therapy: A Pilot Study.
    PloS one, 2016, Volume: 11, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Critical Illness; Drug Monitoring; Female; Humans; Imipenem; Male; Middle Aged; Pilot Projects; Prospective Studies; Renal Replacement Therapy

2016
Is continuous infusion of imipenem always the best choice?
    International journal of antimicrobial agents, 2017, Volume: 49, Issue:3

    Topics: Aged; Anti-Bacterial Agents; Critical Illness; Cross Infection; Female; Gram-Negative Bacteria; Humans; Imipenem; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Plasma; Pneumonia, Bacterial; Staphylococcus aureus; Time Factors

2017
Kinetics of imipenem distribution into the peritoneal fluid of patients with severe peritonitis studied by microdialysis.
    Clinical pharmacokinetics, 2010, Volume: 49, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Ascitic Fluid; Critical Illness; Female; Humans; Imipenem; Male; Microdialysis; Middle Aged; Models, Chemical; Peritonitis; Severity of Illness Index

2010
Patients with Acinetobacter baumannii bloodstream infections are colonized in the gastrointestinal tract with identical strains.
    American journal of infection control, 2010, Volume: 38, Issue:9

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Aged; Anti-Bacterial Agents; Bacteremia; Bacterial Typing Techniques; beta-Lactam Resistance; Blood; Critical Illness; Cross Infection; DNA Fingerprinting; Electrophoresis, Gel, Pulsed-Field; Female; Gastrointestinal Tract; Humans; Imipenem; Male; Middle Aged; Molecular Epidemiology

2010
Comparison of culture media for detection of Acinetobacter baumannii in surveillance cultures of critically-ill patients.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2011, Volume: 30, Issue:11

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anal Canal; Anti-Bacterial Agents; Bacteriological Techniques; Cohort Studies; Critical Illness; Culture Media; Drug Resistance, Multiple, Bacterial; Humans; Imipenem; Infection Control; Intensive Care Units; Sensitivity and Specificity; Sputum

2011
Campylobacter fetus meningitis in a diabetic adult cured by imipenem.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2004, Volume: 23, Issue:9

    Topics: Aged; Campylobacter fetus; Campylobacter Infections; Critical Illness; Diabetes Mellitus, Type 2; Emergency Service, Hospital; Follow-Up Studies; Humans; Imipenem; Infusions, Intravenous; Male; Meningitis, Bacterial; Risk Assessment; Shock, Septic; Treatment Outcome

2004
Hospital-acquired pneumonia in critically ill patients: factors associated with episodes due to imipenem-resistant organisms.
    Infection, 2005, Volume: 33, Issue:3

    Topics: Acinetobacter baumannii; Aged; Anti-Bacterial Agents; Critical Illness; Cross Infection; Drug Resistance, Bacterial; Female; Humans; Imipenem; Male; Middle Aged; Pneumonia, Bacterial; Pseudomonas aeruginosa; Risk Factors; Staphylococcus aureus; Stenotrophomonas maltophilia

2005
[Infections caused by Acinetobacter spp. in critically ill ICU patients].
    Enfermedades infecciosas y microbiologia clinica, 2005, Volume: 23, Issue:9

    Topics: Acinetobacter; Acinetobacter baumannii; Acinetobacter Infections; Adolescent; Adult; Aged; Aged, 80 and over; APACHE; Bacteremia; beta-Lactam Resistance; Child; Comorbidity; Critical Illness; Cross Infection; Drug Resistance, Multiple, Bacterial; Female; Health Surveys; Hospital Mortality; Humans; Imipenem; Incidence; Intensive Care Units; Male; Middle Aged; Postoperative Complications; Prospective Studies; Prosthesis-Related Infections; Spain; Species Specificity

2005
Prospective determination of plasma imipenem concentrations in critically ill children.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:7

    Topics: Anti-Bacterial Agents; Area Under Curve; Bacterial Infections; Child; Child, Preschool; Cilastatin; Cilastatin, Imipenem Drug Combination; Critical Illness; Cross Infection; Drug Combinations; Drug Therapy, Combination; Female; Humans; Imipenem; Infant; Infant, Newborn; Infusions, Intravenous; Male

2006
Combination carbapenem-sulbactam therapy for critically ill patients with multidrug-resistant Acinetobacter baumannii bacteremia: four case reports and an in vitro combination synergy study.
    Pharmacotherapy, 2007, Volume: 27, Issue:11

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Aged; Anti-Bacterial Agents; Bacteremia; Cilastatin; Cilastatin, Imipenem Drug Combination; Critical Illness; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipenem; Male; Meropenem; Microbial Sensitivity Tests; Sulbactam; Taiwan; Thienamycins

2007
Pharmacokinetic profiles of intravenous imipenem/cilastatin during slow hemodialysis in critically ill patients.
    Clinical nephrology, 1994, Volume: 42, Issue:3

    Topics: Aged; Cilastatin; Cilastatin, Imipenem Drug Combination; Critical Illness; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Half-Life; Humans; Imipenem; Infusions, Intravenous; Male; Renal Dialysis; Renal Insufficiency

1994
Seizures in the critically ill: the role of imipenem.
    Epilepsia, 2001, Volume: 42, Issue:12

    Topics: Acute Disease; Anti-Bacterial Agents; Critical Illness; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Hospital Records; Hospitalization; Humans; Imipenem; Incidence; Life Tables; Risk Factors; Seizures; Treatment Outcome

2001
Tissue distribution of imipenem in critically ill patients.
    Clinical pharmacology and therapeutics, 2002, Volume: 71, Issue:5

    Topics: Adult; Aged; Area Under Curve; Critical Illness; Female; Humans; Imipenem; Male; Microbial Sensitivity Tests; Muscles; Thienamycins; Tissue Distribution

2002