imidazole has been researched along with Multiple Myeloma in 1 studies
imidazole: RN given refers to parent cpd
1H-imidazole : An imidazole tautomer which has the migrating hydrogen at position 1.
Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our previous study reported that nitroxoline, an FDA approved antibiotic, showed potential BRD4 inhibitory activity and antiproliferation activity against leukemia cell lines." | 3.91 | Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors. ( Chen, K; Hu, T; Jiang, H; Jiang, X; Luo, C; Luo, X; Qiao, G; Shen, J; Wang, J; Wang, X; Xing, J; Yang, F; Zhang, R; Zheng, M, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xing, J | 1 |
| Zhang, R | 1 |
| Jiang, X | 1 |
| Hu, T | 1 |
| Wang, X | 1 |
| Qiao, G | 1 |
| Wang, J | 1 |
| Yang, F | 1 |
| Luo, X | 1 |
| Chen, K | 1 |
| Shen, J | 1 |
| Luo, C | 1 |
| Jiang, H | 1 |
| Zheng, M | 1 |
1 other study available for imidazole and Multiple Myeloma
| Article | Year |
|---|---|
Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors.
Topics: Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Computer-Aided Design; Drug Design; Human | 2019 |