imidazole has been researched along with Malignant Melanoma in 8 studies
imidazole: RN given refers to parent cpd
1H-imidazole : An imidazole tautomer which has the migrating hydrogen at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present study, we determined whether or not imidazole affects B16 murine melanoma cell migration to prevent melanoma metastasis." | 7.76 | Imidazole inhibits B16 melanoma cell migration via degradation of beta-catenin. ( Baek, KJ; Jeong, YM; Kim, DS; Kim, SY; Kwon, NS; Li, H; Yun, HY, 2010) |
| "1) by imidazole was determined in cultured B16/C3 melanoma cells." | 7.67 | Retinoic acid blockade of imidazole-induced tyrosinase expression in B16 melanoma cultures: similar effects of the active retinoid and triiodothyronine. ( Kline, EL; Smith, TJ; Warren, JT, 1989) |
| "Investigations with mouse melanoma B16/C3 cell cultures have suggested that imidazole or a derivative thereof can facilitate expression of the tyrosinase (EC 1." | 7.67 | Triiodothyronine repression of imidazole-induced tyrosinase expression in B16 melanoma cells. ( Carland, K; Kline, EL; Smith, TJ, 1986) |
| "3,3',5-L-triiodothyronine (T3) can inhibit tyrosinase activity in B16/C3 melanoma cells in culture and block the induction of that enzyme by imidazole (Endocrinol." | 7.67 | 3,3',5-L-triiodothyronine but not L-thyroxine can block the induction of tyrosinase by imidazole in cultured B16 melanoma cells. ( Kline, EL; Smith, TJ, 1988) |
| "In the present study, we determined whether or not imidazole affects B16 murine melanoma cell migration to prevent melanoma metastasis." | 3.76 | Imidazole inhibits B16 melanoma cell migration via degradation of beta-catenin. ( Baek, KJ; Jeong, YM; Kim, DS; Kim, SY; Kwon, NS; Li, H; Yun, HY, 2010) |
| "1) by imidazole was determined in cultured B16/C3 melanoma cells." | 3.67 | Retinoic acid blockade of imidazole-induced tyrosinase expression in B16 melanoma cultures: similar effects of the active retinoid and triiodothyronine. ( Kline, EL; Smith, TJ; Warren, JT, 1989) |
| "Investigations with mouse melanoma B16/C3 cell cultures have suggested that imidazole or a derivative thereof can facilitate expression of the tyrosinase (EC 1." | 3.67 | Triiodothyronine repression of imidazole-induced tyrosinase expression in B16 melanoma cells. ( Carland, K; Kline, EL; Smith, TJ, 1986) |
| "3,3',5-L-triiodothyronine (T3) can inhibit tyrosinase activity in B16/C3 melanoma cells in culture and block the induction of that enzyme by imidazole (Endocrinol." | 3.67 | 3,3',5-L-triiodothyronine but not L-thyroxine can block the induction of tyrosinase by imidazole in cultured B16 melanoma cells. ( Kline, EL; Smith, TJ, 1988) |
| "1) activity of cell-free extracts (TyH) of B16 melanoma cells cultured in the presence of 5 to 10 mM ammonium chloride was considerably higher than that of cells from control cultures." | 3.66 | Stimulation of tyrosinase activity of cultured melanoma cells by lysosomotropic agents. ( Oikawa, A; Saeki, H, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, TY | 1 |
| Huang, Q | 1 |
| Huang, ZS | 1 |
| Hu, MH | 1 |
| Tan, JH | 1 |
| Deleuze-Masquefa, C | 1 |
| Moarbess, G | 1 |
| Khier, S | 1 |
| David, N | 1 |
| Gayraud-Paniagua, S | 1 |
| Bressolle, F | 1 |
| Pinguet, F | 1 |
| Bonnet, PA | 1 |
| Jeong, YM | 1 |
| Li, H | 1 |
| Kim, SY | 1 |
| Yun, HY | 1 |
| Baek, KJ | 1 |
| Kwon, NS | 1 |
| Kim, DS | 1 |
| Niculescu-Duvaz, D | 1 |
| Niculescu-Duvaz, I | 1 |
| Suijkerbuijk, BM | 1 |
| Ménard, D | 1 |
| Zambon, A | 1 |
| Davies, L | 1 |
| Pons, JF | 1 |
| Whittaker, S | 1 |
| Marais, R | 1 |
| Springer, CJ | 1 |
| Saeki, H | 1 |
| Oikawa, A | 1 |
| Smith, TJ | 3 |
| Warren, JT | 1 |
| Kline, EL | 3 |
| Carland, K | 1 |
8 other studies available for imidazole and Malignant Melanoma
| Article | Year |
|---|---|
A drug-like imidazole-benzothiazole conjugate inhibits malignant melanoma by stabilizing the c-MYC G-quadruplex.
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzothiazoles; Cell Cycle Checkpoints; Cell Proliferatio | 2020 |
New imidazo[1,2-a]quinoxaline derivatives: synthesis and in vitro activity against human melanoma.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Human | 2009 |
Imidazole inhibits B16 melanoma cell migration via degradation of beta-catenin.
Topics: Animals; Antineoplastic Agents; beta Catenin; Blotting, Western; Cell Line, Tumor; Cell Movement; Im | 2010 |
Potent BRAF kinase inhibitors based on 2,4,5-trisubstituted imidazole with naphthyl and benzothiophene 4-substituents.
Topics: Benzofurans; Cell Line, Tumor; Cell Survival; Humans; Imidazoles; Melanoma; Naphthols; Protein Kinas | 2013 |
Stimulation of tyrosinase activity of cultured melanoma cells by lysosomotropic agents.
Topics: Ammonium Chloride; Animals; Catechol Oxidase; Cell Line; Chloroquine; Cycloheximide; Ethylamines; Hy | 1983 |
Retinoic acid blockade of imidazole-induced tyrosinase expression in B16 melanoma cultures: similar effects of the active retinoid and triiodothyronine.
Topics: Animals; Catechol Oxidase; Cell Line; Enzyme Induction; Imidazoles; Melanoma; Mice; Monophenol Monoo | 1989 |
Triiodothyronine repression of imidazole-induced tyrosinase expression in B16 melanoma cells.
Topics: Animals; Catechol Oxidase; Cell Division; Cell Line; Dactinomycin; Dose-Response Relationship, Drug; | 1986 |
3,3',5-L-triiodothyronine but not L-thyroxine can block the induction of tyrosinase by imidazole in cultured B16 melanoma cells.
Topics: Animals; Catechol Oxidase; Cells, Cultured; Enzyme Induction; Imidazoles; Melanoma; Mice; Monophenol | 1988 |