imidazole has been researched along with Helicobacter Infections in 3 studies
imidazole: RN given refers to parent cpd
1H-imidazole : An imidazole tautomer which has the migrating hydrogen at position 1.
Helicobacter Infections: Infections with organisms of the genus HELICOBACTER, particularly, in humans, HELICOBACTER PYLORI. The clinical manifestations are focused in the stomach, usually the gastric mucosa and antrum, and the upper duodenum. This infection plays a major role in the pathogenesis of type B gastritis and peptic ulcer disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clarithromycin resistance was less frequent than expected." | 2.75 | Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection. ( Chen, A; Graham, DY; Hsu, PI; Hung, WC; Kuo, CH; Opekun, AR; Wang, SS; Wu, DC; Wu, IC; Wu, JY, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, DC | 1 |
| Hsu, PI | 1 |
| Wu, JY | 1 |
| Opekun, AR | 1 |
| Kuo, CH | 1 |
| Wu, IC | 1 |
| Wang, SS | 1 |
| Chen, A | 1 |
| Hung, WC | 1 |
| Graham, DY | 1 |
| Basarab, GS | 1 |
| Hill, P | 1 |
| Eyermann, CJ | 1 |
| Gowravaram, M | 1 |
| Käck, H | 1 |
| Osimoni, E | 1 |
| Buzás, GM | 1 |
| Józan, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparing the Efficacy and Impact on Gastrointestinal Microbiome of Reverse Hybrid Therapy and Bismuth Quadruple Therapy in Helicobacter Pylori Eradication[NCT02547038] | 352 participants (Actual) | Interventional | 2015-02-28 | Completed | |||
| A Prospective Randomized Trial of Levofloxacin-amoxicillin Triple Therapy vs. Levofloxacin-tetracycline Quadruple Therapy in Second-line Helicobacter Pylori Treatment[NCT02978157] | 102 participants (Actual) | Interventional | 2015-02-28 | Completed | |||
| Phase 4, Prospective, Randomized and Comparative Study Comparing Sequential and Concomitant Therapy for Helicobacter Pylori Eradication in Routine Clinical Practice[NCT01273441] | Phase 4 | 338 participants (Actual) | Interventional | 2010-12-31 | Completed | ||
| Comparison of Hybrid and Bismuth Containing Quadruple Therapies for Helicobacter Pylori Eradication: a Randomized Controlled Trial[NCT02541864] | 330 participants (Actual) | Interventional | 2013-07-31 | Completed | |||
| Comparison of Two Rescue Therapies for Helicobacter Pylori Infection - A Multicenter Randomized Controlled Trial[NCT02547012] | 51 participants (Actual) | Interventional | 2013-11-30 | Completed | |||
| Comparison of 12-day Reverse Hybrid Therapy and 12-day Standard Triple Therapy for Helicobacter Pylori Infection - a Randomized Controlled Trial (REHYTRI Study)[NCT02359435] | 440 participants (Actual) | Interventional | 2012-10-31 | Completed | |||
| "Phase 4, Prospective, Randomized Study Comparing 14-day Non-bismuth Quadruple Hybrid and Concomitant Therapies for Helicobacter Pylori Eradication in Settings With High Clarithromycin Resistance"[NCT01464060] | Phase 4 | 400 participants (Anticipated) | Interventional | 2011-09-30 | Recruiting | ||
| Increased Second-line Eradication Rate of Helicobacter Pylori by Adding N-acetylcystein or Metronidazole to the Conventional Triple Therapy.[NCT01572597] | Phase 4 | 120 participants (Anticipated) | Interventional | 2011-06-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Evaluate eradication outcome by endoscopy urease test and histology or urea breath test (Number of Participants With Complete Eradication of Helicobacter Pylori) (NCT02547038)
Timeframe: sixth week after the end of anti- H. pylori therapy
| Intervention | participants (Number) |
|---|---|
| Pantoprazole+Bismuth+Tetra+Metro | 169 |
| (Panto+Amox+Clar+Metr)+(Panto+Amox) | 170 |
Number of participants with negative H pylori status in follow-up tests as a measure of successful eradication (NCT02978157)
Timeframe: six weeks after the end of anti-H pylori therapy.
| Intervention | participants (Number) |
|---|---|
| Esomeprazole+Amox+Levo | 36 |
| Esomeprazole+Bismuth+Tetra+Levo | 49 |
Repeated endoscopy with rapid urease test, histological examination and culture or urea breath tests are conducted to assess H. pylori status. (NCT02541864)
Timeframe: at the 6th week after the end of anti- H. pylori therapy
| Intervention | participants (Number) |
|---|---|
| Pantoprazole+Bismuth+Tetra+Metro | 154 |
| Hybrid Therapy | 154 |
Evaluate eradication outcome by endoscopy urease test and histology or urea breath test (NCT02547012)
Timeframe: six weeks after the end of anti-H pylori therapy.
| Intervention | participants (Number) |
|---|---|
| Esomeprazole+Amox+Levo+Tetra | 13 |
| Esomeprazole+Amox+Levo | 21 |
Evaluate eradication outcome by endoscopy urease test and histology or urea breath test (NCT02359435)
Timeframe: at the 6th week after the end of anti- H. pylori therapy
| Intervention | participants (Number) |
|---|---|
| Reverse Hybrid Therapy | 206 |
| Standard Triple Therapy | 191 |
1 review available for imidazole and Helicobacter Infections
| Article | Year |
|---|---|
[Eradication of Helicobacter pylori infection in Europe: a meta-analysis based on congress abstracts, 1997-2002].
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Eu | 2004 |
1 trial available for imidazole and Helicobacter Infections
| Article | Year |
|---|---|
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
Sequential and concomitant therapy with four drugs is equally effective for eradication of H pylori infection.
Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Resistance, Bacterial; | 2010 |
1 other study available for imidazole and Helicobacter Infections
| Article | Year |
|---|---|
Design of inhibitors of Helicobacter pylori glutamate racemase as selective antibacterial agents: incorporation of imidazoles onto a core pyrazolopyrimidinedione scaffold to improve bioavailabilty.
Topics: Administration, Oral; Amino Acid Isomerases; Animals; Anti-Bacterial Agents; Biological Availability | 2012 |