imidazole has been researched along with Disease Models, Animal in 22 studies
imidazole: RN given refers to parent cpd
1H-imidazole : An imidazole tautomer which has the migrating hydrogen at position 1.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of new and potent NOS inhibitors, S-methyl-L-thiocitrulline (S-Me-TC), 3-bromo 7-nitro indazole (3-Br-7-NI), and 1-(2-trifluoromethylphenyl) imidazole (TRIM), were examined on the pilocarpine-induced seizures in mice." | 3.69 | Anticonvulsant activity of new and potent inhibitors of nitric oxide synthase. ( De Vries, R; Dzoljic, E; Dzoljic, MR, 1997) |
| "Malaria is a serious disease and is one of the most alarming public health issues." | 1.51 | Efficacy of TLR7 agonistic imidazoquinoline as immunochemotherapeutic agent against P. Berghei ANKA infected rodent host. ( Bagai, U; Kaur, S; Kaushik, D; Salunke, DB; Saroa, R, 2019) |
| " Long-term administration of copper significantly accelerated the onset and progression of spontaneous prion disease in TgMHu2ME199K mice and caused marked irritability and cerebellar associated tip-toe walking in PrP(0/0) mice, while wt mice were not affected." | 1.38 | Copper is toxic to PrP-ablated mice and exacerbates disease in a mouse model of E200K genetic prion disease. ( Binyamin, O; Canello, T; Cohen, E; Frid, K; Friedman-Levi, Y; Gabizon, R; Mizrahi, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 12 (54.55) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| He, L | 1 |
| Huang, G | 1 |
| Liu, H | 1 |
| Sang, C | 1 |
| Liu, X | 1 |
| Chen, T | 1 |
| Zhao, YT | 1 |
| Chen, XX | 1 |
| Jiang, WL | 1 |
| Li, Y | 1 |
| Fei, J | 1 |
| Li, CY | 1 |
| Masuoka, N | 1 |
| Lei, C | 1 |
| Li, H | 1 |
| Hisatsune, T | 1 |
| Gurjar, AS | 1 |
| Darekar, MN | 1 |
| Yeong, KY | 1 |
| Ooi, L | 1 |
| Liu, L | 1 |
| Hu, Y | 1 |
| Lu, J | 1 |
| Wang, G | 1 |
| Saroa, R | 1 |
| Kaushik, D | 1 |
| Bagai, U | 1 |
| Kaur, S | 1 |
| Salunke, DB | 1 |
| Banerjee, A | 1 |
| Narayana, L | 1 |
| Raje, FA | 1 |
| Pisal, DV | 1 |
| Kadam, PA | 1 |
| Gullapalli, S | 1 |
| Kumar, H | 1 |
| More, SV | 1 |
| Bajpai, M | 1 |
| Sangana, RR | 1 |
| Jadhav, S | 1 |
| Gudi, GS | 1 |
| Khairatkar-Joshi, N | 1 |
| Merugu, RR | 1 |
| Voleti, SR | 1 |
| Gharat, LA | 1 |
| Chung, JY | 1 |
| Lee, JW | 1 |
| Ryu, CH | 1 |
| Min, HK | 1 |
| Yoon, YJ | 1 |
| Lim, MJ | 1 |
| Park, CH | 1 |
| Igarashi, J | 1 |
| Fukuda, N | 1 |
| Inoue, T | 1 |
| Nakai, S | 1 |
| Saito, K | 1 |
| Fujiwara, K | 1 |
| Matsuda, H | 1 |
| Ueno, T | 1 |
| Matsumoto, Y | 1 |
| Watanabe, T | 1 |
| Nagase, H | 1 |
| Bando, T | 1 |
| Sugiyama, H | 1 |
| Itoh, T | 1 |
| Soma, M | 1 |
| Kammeyer, A | 1 |
| Bos, JD | 1 |
| Teunissen, MB | 1 |
| June, RK | 1 |
| Gogoi, K | 1 |
| Eguchi, A | 1 |
| Cui, XS | 1 |
| Dowdy, SF | 1 |
| Dyckman, AJ | 1 |
| Langevine, CM | 1 |
| Quesnelle, C | 1 |
| Kempson, J | 1 |
| Guo, J | 1 |
| Gill, P | 1 |
| Spergel, SH | 1 |
| Watterson, SH | 1 |
| Li, T | 1 |
| Nirschl, DS | 1 |
| Gillooly, KM | 1 |
| Pattoli, MA | 1 |
| McIntyre, KW | 1 |
| Chen, L | 1 |
| McKinnon, M | 1 |
| Dodd, JH | 1 |
| Barrish, JC | 1 |
| Burke, JR | 1 |
| Pitts, WJ | 1 |
| Manning, DD | 1 |
| Cioffi, CL | 1 |
| Usyatinsky, A | 1 |
| Fitzpatrick, K | 1 |
| Masih, L | 1 |
| Guo, C | 1 |
| Zhang, Z | 1 |
| Choo, SH | 1 |
| Sikkander, MI | 1 |
| Ryan, KN | 1 |
| Naginskaya, J | 1 |
| Hassler, C | 1 |
| Dobritsa, S | 1 |
| Wierschke, JD | 1 |
| Earley, WG | 1 |
| Butler, AS | 1 |
| Brady, CA | 1 |
| Barnes, NM | 1 |
| Cohen, ML | 1 |
| Guzzo, PR | 1 |
| Shimizu, H | 1 |
| Yamasaki, T | 1 |
| Yoneda, Y | 1 |
| Muro, F | 1 |
| Hamada, T | 1 |
| Yasukochi, T | 1 |
| Tanaka, S | 1 |
| Toki, T | 1 |
| Yokoyama, M | 1 |
| Morishita, K | 1 |
| Iimura, S | 1 |
| Canello, T | 1 |
| Friedman-Levi, Y | 1 |
| Mizrahi, M | 1 |
| Binyamin, O | 1 |
| Cohen, E | 1 |
| Frid, K | 1 |
| Gabizon, R | 1 |
| Galley, G | 1 |
| Stalder, H | 1 |
| Goergler, A | 1 |
| Hoener, MC | 1 |
| Norcross, RD | 1 |
| Fukuda, S | 1 |
| Midoro, K | 1 |
| Kamei, T | 1 |
| Gyoten, M | 1 |
| Kawano, Y | 1 |
| Ashida, Y | 1 |
| Nagaya, H | 1 |
| Crane, L | 1 |
| Anastassiadou, M | 1 |
| El Hage, S | 1 |
| Stigliani, JL | 1 |
| Baziard-Mouysset, G | 1 |
| Payard, M | 1 |
| Leger, JM | 1 |
| Bizot-Espiard, JG | 1 |
| Ktorza, A | 1 |
| Caignard, DH | 1 |
| Renard, P | 1 |
| Abdul-Ghani, AS | 1 |
| Abu-Hijleh, AL | 1 |
| Nahas, N | 1 |
| Amin, R | 1 |
| Dzoljic, E | 1 |
| De Vries, R | 1 |
| Dzoljic, MR | 1 |
| Miyachi, H | 1 |
| Kiyota, H | 1 |
| Uchiki, H | 1 |
| Segawa, M | 1 |
| Peterson, JW | 1 |
| King, D | 1 |
| Ezell, EL | 1 |
| Rogers, M | 1 |
| Gessell, D | 1 |
| Hoffpauer, J | 1 |
| Reuss, L | 1 |
| Chopra, AK | 1 |
| Gorenstein, D | 1 |
1 review available for imidazole and Disease Models, Animal
| Article | Year |
|---|---|
Influence of Imidazole-Dipeptides on Cognitive Status and Preservation in Elders: A Narrative Review.
Topics: Aged; Alzheimer Disease; Animals; Anserine; Brain; Carnosine; Cognition; Cognitive Dysfunction; Diet | 2021 |
21 other studies available for imidazole and Disease Models, Animal
| Article | Year |
|---|---|
Highly bioactive zeolitic imidazolate framework-8-capped nanotherapeutics for efficient reversal of reperfusion-induced injury in ischemic stroke.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cell Cycle; Chemistry Techniques, Synthe | 2020 |
Near-Infrared Fluorescence MOF Nanoprobe for Adenosine Triphosphate-Guided Imaging in Colitis.
Topics: Adenosine Triphosphate; Animals; Colitis; Dextran Sulfate; Disease Models, Animal; Fluorescent Dyes; | 2020 |
In silico studies, synthesis and pharmacological evaluation to explore multi-targeted approach for imidazole analogues as potential cholinesterase inhibitors with neuroprotective role for Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; | 2018 |
An imidazole coumarin derivative enhances the antiviral response to spring viremia of carp virus infection in zebrafish.
Topics: Animals; Antiviral Agents; Coumarins; Disease Models, Animal; Half-Life; Imidazoles; Immunity, Innat | 2019 |
Efficacy of TLR7 agonistic imidazoquinoline as immunochemotherapeutic agent against P. Berghei ANKA infected rodent host.
Topics: Animals; Antimalarials; Chloroquine; Disease Models, Animal; Imidazoles; Interferon-gamma; Interleuk | 2019 |
Discovery of benzo[d]imidazo[5,1-b]thiazole as a new class of phosphodiesterase 10A inhibitors.
Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Dizocilpine Maleate; Drug Evaluation, Preclin | 2013 |
1-[2-(4-Benzyloxyphenoxy)Ethyl]Imidazole inhibits monoamine oxidase B and protects against neuronal loss and behavioral impairment in rodent models of Parkinson's disease.
Topics: Animals; Cell Count; Disease Models, Animal; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Inbre | 2015 |
Preclinical Study of Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Hypertrophic Scars in a Common Marmoset Primate Model.
Topics: Animals; Base Sequence; Binding Sites; Callithrix; Cicatrix, Hypertrophic; Disease Models, Animal; G | 2015 |
Postelicitation model of allergic contact dermatitis for predicting the efficacy of topical drugs.
Topics: Administration, Topical; Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Carboxylic Acid | 2009 |
Synthesis of a pH-sensitive nitrilotriacetic linker to peptide transduction domains to enable intracellular delivery of histidine imidazole ring-containing macromolecules.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Gene Expres | 2010 |
Imidazo[4,5-d]thiazolo[5,4-b]pyridine based inhibitors of IKK2: synthesis, SAR, PK/PD and activity in a preclinical model of rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Female; | 2011 |
Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome.
Topics: Animals; Cell Line; Disease Models, Animal; Humans; Imidazoles; Indoles; Irritable Bowel Syndrome; M | 2011 |
Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 3: exploration of effective compounds in arthritis models.
Topics: Administration, Oral; Animals; Arthritis, Experimental; Disease Models, Animal; Drug Evaluation, Pre | 2011 |
Copper is toxic to PrP-ablated mice and exacerbates disease in a mouse model of E200K genetic prion disease.
Topics: Age Factors; Animals; Cells, Cultured; Cerebellum; Chromatography, Affinity; Copper; Copper Sulfate; | 2012 |
Optimisation of imidazole compounds as selective TAAR1 agonists: discovery of RO5073012.
Topics: Administration, Oral; Aniline Compounds; Animals; Behavior, Animal; Disease Models, Animal; Drug Eva | 2012 |
Inhibition of allergic dermal inflammation by the novel imidazopyridazine derivative TAK-427 in a guinea pig experimental model of eczema.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dermatitis, Aller | 2002 |
Design and synthesis of novel imidazoline derivatives with potent antihyperglycemic activity in a rat model of type 2 diabetes.
Topics: Animals; Blood Glucose; Cattle; Crystallography, X-Ray; Diabetes Mellitus, Type 2; Disease Models, A | 2006 |
Hypoglycemic effect of copper(II) acetate imidazole complexes.
Topics: Animals; Binding Sites; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dose | 1996 |
Anticonvulsant activity of new and potent inhibitors of nitric oxide synthase.
Topics: Animals; Anticonvulsants; Citrulline; Disease Models, Animal; Enzyme Inhibitors; Imidazoles; Male; M | 1997 |
Synthesis and antimuscarinic activity of a series of 4-(1-Imidazolyl)-2,2-diphenylbutyramides: discovery of potent and subtype-selective antimuscarinic agents.
Topics: Animals; Disease Models, Animal; Guinea Pigs; Imidazoles; In Vitro Techniques; Molecular Structure; | 1999 |
Cholera toxin-induced PGE(2) activity is reduced by chemical reaction with L-histidine.
Topics: Animals; Binding Sites; Body Fluids; CHO Cells; Cholera; Cholera Toxin; Cricetinae; Cyclic AMP; Dino | 2001 |