imidazole has been researched along with Diabetes Mellitus, Type 2 in 3 studies
imidazole: RN given refers to parent cpd
1H-imidazole : An imidazole tautomer which has the migrating hydrogen at position 1.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Compound 4d, a novel TGR5 agonist, in combination with Sitagliptin, a DPP-4 inhibitor, has demonstrated an adequate GLP-1 secretion and glucose lowering effect in animal models, suggesting a potential clinical option in treatment of type-2 diabetes." | 1.48 | Evaluation of novel TGR5 agonist in combination with Sitagliptin for possible treatment of type 2 diabetes. ( Agarwal, S; Bhayani, H; Deshmukh, P; Giri, P; Giri, S; Jain, M; Kulkarni, N; Kumar, J; Sasane, S; Soman, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agarwal, S | 1 |
| Sasane, S | 1 |
| Kumar, J | 1 |
| Deshmukh, P | 1 |
| Bhayani, H | 1 |
| Giri, P | 1 |
| Giri, S | 1 |
| Soman, S | 1 |
| Kulkarni, N | 1 |
| Jain, M | 1 |
| Stevens, BD | 1 |
| Litchfield, J | 1 |
| Pfefferkorn, JA | 1 |
| Atkinson, K | 1 |
| Perreault, C | 1 |
| Amor, P | 1 |
| Bahnck, K | 1 |
| Berliner, MA | 1 |
| Calloway, J | 1 |
| Carlo, A | 1 |
| Derksen, DR | 1 |
| Filipski, KJ | 1 |
| Gumkowski, M | 1 |
| Jassal, C | 1 |
| MacDougall, M | 1 |
| Murphy, B | 1 |
| Nkansah, P | 1 |
| Pettersen, J | 1 |
| Rotter, C | 1 |
| Zhang, Y | 1 |
| Crane, L | 1 |
| Anastassiadou, M | 1 |
| El Hage, S | 1 |
| Stigliani, JL | 1 |
| Baziard-Mouysset, G | 1 |
| Payard, M | 1 |
| Leger, JM | 1 |
| Bizot-Espiard, JG | 1 |
| Ktorza, A | 1 |
| Caignard, DH | 1 |
| Renard, P | 1 |
3 other studies available for imidazole and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Evaluation of novel TGR5 agonist in combination with Sitagliptin for possible treatment of type 2 diabetes.
Topics: Animals; Binding Sites; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glucagon-Like | 2018 |
Discovery of an intravenous hepatoselective glucokinase activator for the treatment of inpatient hyperglycemia.
Topics: Allosteric Regulation; Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Drug Evaluation, Preclin | 2013 |
Design and synthesis of novel imidazoline derivatives with potent antihyperglycemic activity in a rat model of type 2 diabetes.
Topics: Animals; Blood Glucose; Cattle; Crystallography, X-Ray; Diabetes Mellitus, Type 2; Disease Models, A | 2006 |