imidazole and Creutzfeldt-Jakob Syndrome
imidazole has been researched along with Creutzfeldt-Jakob Syndrome in 1 studies
imidazole: RN given refers to parent cpd
1H-imidazole : An imidazole tautomer which has the migrating hydrogen at position 1.
Creutzfeldt-Jakob Syndrome: A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
" Long-term administration of copper significantly accelerated the onset and progression of spontaneous prion disease in TgMHu2ME199K mice and caused marked irritability and cerebellar associated tip-toe walking in PrP(0/0) mice, while wt mice were not affected." | 1.38 | Copper is toxic to PrP-ablated mice and exacerbates disease in a mouse model of E200K genetic prion disease. ( Binyamin, O; Canello, T; Cohen, E; Frid, K; Friedman-Levi, Y; Gabizon, R; Mizrahi, M, 2012) |
Research
Studies (1)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Canello, T | 1 |
Friedman-Levi, Y | 1 |
Mizrahi, M | 1 |
Binyamin, O | 1 |
Cohen, E | 1 |
Frid, K | 1 |
Gabizon, R | 1 |
Other Studies
1 other study available for imidazole and Creutzfeldt-Jakob Syndrome
Article | Year |
---|---|
Copper is toxic to PrP-ablated mice and exacerbates disease in a mouse model of E200K genetic prion disease.
Topics: Age Factors; Animals; Cells, Cultured; Cerebellum; Chromatography, Affinity; Copper; Copper Sulfate; | 2012 |