imidazole has been researched along with Asthma in 3 studies
imidazole: RN given refers to parent cpd
1H-imidazole : An imidazole tautomer which has the migrating hydrogen at position 1.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a randomized, double-blind, placebo-controlled study, the acute and long-term effects of the reduction of thromboxane A2 (TxA2) synthesis on airway sensitivity and maximal airway narrowing in response to methacholine was evaluated in 12 subjects with mild-to-moderate stable asthma, using imidazole salycilate (IS), an anti-inflammatory drug which selectively inhibits the TxA2 synthetase." | 9.08 | Ineffectiveness of a four week treatment with the thromboxane synthetase inhibitor, imidazole salycilate, in reducing airway hyperresponsiveness to methacholine in asthmatics. ( Casucci, G; Dottorini, ML; Mezzasoma, AM; Peccini, F; Sorbini, CA; Tantucci, C, 1997) |
| "In a randomized, double-blind, placebo-controlled study, the acute and long-term effects of the reduction of thromboxane A2 (TxA2) synthesis on airway sensitivity and maximal airway narrowing in response to methacholine was evaluated in 12 subjects with mild-to-moderate stable asthma, using imidazole salycilate (IS), an anti-inflammatory drug which selectively inhibits the TxA2 synthetase." | 5.08 | Ineffectiveness of a four week treatment with the thromboxane synthetase inhibitor, imidazole salycilate, in reducing airway hyperresponsiveness to methacholine in asthmatics. ( Casucci, G; Dottorini, ML; Mezzasoma, AM; Peccini, F; Sorbini, CA; Tantucci, C, 1997) |
| "We describe the effects of pH on the structure and bioavailability of MIDD0301, an oral lead compound for asthma." | 1.56 | The Effects of pH on the Structure and Bioavailability of Imidazobenzodiazepine-3-Carboxylate MIDD0301. ( Arnold, LA; Cook, JM; Knutson, DE; Li, G; Mian, MY; Mikulsky, BN; Roni, MSR; Stafford, DC; Zahn, NM, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Roni, MSR | 1 |
| Li, G | 1 |
| Mikulsky, BN | 1 |
| Knutson, DE | 1 |
| Mian, MY | 1 |
| Zahn, NM | 1 |
| Cook, JM | 1 |
| Stafford, DC | 1 |
| Arnold, LA | 1 |
| KERR, JW | 1 |
| Peccini, F | 1 |
| Dottorini, ML | 1 |
| Casucci, G | 1 |
| Mezzasoma, AM | 1 |
| Sorbini, CA | 1 |
| Tantucci, C | 1 |
1 trial available for imidazole and Asthma
| Article | Year |
|---|---|
Ineffectiveness of a four week treatment with the thromboxane synthetase inhibitor, imidazole salycilate, in reducing airway hyperresponsiveness to methacholine in asthmatics.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchial Hyperreactivity; Bronchial P | 1997 |
2 other studies available for imidazole and Asthma
| Article | Year |
|---|---|
The Effects of pH on the Structure and Bioavailability of Imidazobenzodiazepine-3-Carboxylate MIDD0301.
Topics: Animals; Asthma; Azepines; Benzodiazepines; Biological Availability; Brain; Carboxylic Acids; Female | 2020 |
IDENTIFICATION OF HISTAMINE METABOLITE 1-METHYL, 4-IMIDAZOLE ACETIC ACID IN HUMAN URINE AND ITS ABSENCE IN STATUS ASTHMATICUS.
Topics: Acetates; Adrenocorticotropic Hormone; Animals; Asthma; Autoradiography; Carbon Isotopes; Chromatogr | 1964 |