imidazole has been researched along with American Trypanosomiasis in 5 studies
imidazole: RN given refers to parent cpd
1H-imidazole : An imidazole tautomer which has the migrating hydrogen at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "People with Chagas disease (American Trypanosomiasis) may develop progressive and potentially lethal heart conditions." | 2.43 | Trypanocidal drugs for late stage, symptomatic Chagas disease (Trypanosoma cruzi infection). ( Reyes, PA; Vallejo, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beltran-Hortelano, I | 1 |
| Alcolea, V | 1 |
| Font, M | 1 |
| Pérez-Silanes, S | 1 |
| Ghashghaei, O | 1 |
| Kielland, N | 1 |
| Revés, M | 1 |
| Taylor, MC | 1 |
| Kelly, JM | 1 |
| Di Pietro, O | 1 |
| Muñoz-Torrero, D | 1 |
| Pérez, B | 1 |
| Lavilla, R | 1 |
| Gopi, E | 1 |
| Kumar, T | 1 |
| Menna-Barreto, RF | 1 |
| Valença, WO | 1 |
| da Silva Júnior, EN | 1 |
| Namboothiri, IN | 1 |
| Salerno, A | 1 |
| Celentano, AM | 1 |
| López, J | 1 |
| Lara, V | 1 |
| Gaozza, C | 1 |
| Balcazar, DE | 1 |
| Carrillo, C | 1 |
| Frank, FM | 1 |
| Blanco, MM | 1 |
| Reyes, PA | 1 |
| Vallejo, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Etiologic Treatment With Benznidazole in Adult Patients With Chronic Chagas Disease. A Randomized Double Blind Clinical Trial[NCT02386358] | Phase 3 | 910 participants (Actual) | Interventional | 1999-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for imidazole and American Trypanosomiasis
| Article | Year |
|---|---|
The role of imidazole and benzimidazole heterocycles in Chagas disease: A review.
Topics: Animals; Benzimidazoles; Chagas Disease; Drug Discovery; Humans; Imidazoles | 2020 |
Trypanocidal drugs for late stage, symptomatic Chagas disease (Trypanosoma cruzi infection).
Topics: Chagas Cardiomyopathy; Chagas Disease; Chronic Disease; Clinical Trials as Topic; Humans; Imidazoles | 2005 |
3 other studies available for imidazole and American Trypanosomiasis
| Article | Year |
|---|---|
Tetrasubstituted Imidazolium Salts as Potent Antiparasitic Agents against African and American Trypanosomiases.
Topics: Animals; Cell Survival; Chagas Disease; Humans; Imidazoles; Myoblasts; Parasitic Sensitivity Tests; | 2018 |
Imidazoles from nitroallylic acetates and α-bromonitroalkenes with amidines: synthesis and trypanocidal activity studies.
Topics: Acetates; Amidines; Animals; Chagas Disease; Dose-Response Relationship, Drug; Imidazoles; Mice; Mol | 2015 |
Novel 2-arylazoimidazole derivatives as inhibitors of Trypanosoma cruzi proliferation: Synthesis and evaluation of their biological activity.
Topics: Alkylation; Animals; Cell Line; Chagas Disease; Humans; Imidazoles; Male; Mice; Mice, Inbred BALB C; | 2017 |